A5071532096- Pharmaceutical Practices and Patient Outcomes
- Medication Adherence and Compliance
- Diabetes Management and Education
- RNA Interference and Gene Delivery
- Pharmaceutical studies and practices
- Gastroesophageal reflux and treatments
- Pain Management and Opioid Use
- Patient Safety and Medication Errors
- Pediatric Pain Management Techniques
- Virus-based gene therapy research
- Health Literacy and Information Accessibility
- Interprofessional Education and Collaboration
- Innovations in Medical Education
- Advanced biosensing and bioanalysis techniques
- Antibiotic Use and Resistance
- Musculoskeletal pain and rehabilitation
- Palliative Care and End-of-Life Issues
- Pain Management and Placebo Effect
- Primary Care and Health Outcomes
- Pneumonia and Respiratory Infections
- Water resources management and optimization
- Infant Development and Preterm Care
- Helicobacter pylori-related gastroenterology studies
- Fiber-reinforced polymer composites
- Mechanical Behavior of Composites
Curtin University
2016-2025
MIT Lincoln Laboratory
2015-2024
Orange County School
2023
John Wiley & Sons (United States)
2023
GreenLight Biosciences (United States)
2022
University of KwaZulu-Natal
2010-2022
Austin Health
2018-2020
Monash University
2018-2020
University of Waterloo
2017
National Physical Laboratory
2016
Background: The abundance of health information available online provides consumers with greater access to pertinent the management conditions. This is particularly important given an increasing drive for consumer-focused care models globally, especially in chronic conditions, and recognition challenges faced by lay finding, understanding, acting on sourced online. There a paucity literature exploring navigational needs regards accessing information. Further, existing interventions appear be...
Background: The Internet provides a platform to access health information and support self-management by consumers with chronic conditions. Despite recognized barriers accessing Web-based information, there is lack of research quantitatively exploring whether report difficulty finding desired on the these would like assistance (ie, navigational needs). Understanding needs can provide basis for interventions guiding quality resources. Objective: We aimed (1) estimate proportion among seekers...
Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk heart disease. Although statins highly effective in removing from blood, their consumption has been linked potential adverse effects some individuals. The most common events associated with statin intolerance myopathy increased developing type 2 diabetes mellitus. However, pathological mechanism through which cause these is not well understood. Using murine model, we describe for first time profound...
ABSTRACT Adeno-associated virus type 2 (AAV2) has proven to be a valuable vector for gene therapy. Characterization of the functional domains AAV capsid proteins can facilitate our understanding viral tissue tropism, immunoreactivity, entry, and DNA packaging, all which are important issues generating improved vectors. To obtain comprehensive genetic map gene, we have constructed 93 mutants at 59 different positions in by site-directed mutagenesis. Several types were studied, including...
ABSTRACT Proton pump inhibitors (PPIs) are widely used in the elderly. Recent studies have suggested that long-term PPI therapy is associated with fractures elderly, however mechanism remains unknown. We investigated association between ≥1 year and fracture risk factors including bone structure, falls, balance-related function a post hoc analysis of longitudinal population-based prospective cohort elderly postmenopausal women replicated findings second study falling women. Long-term was...
About half of all patients taking antihypertensives discontinue treatment by 12 months. There is potential for substantial health gains at both individual and population levels through improved adherence. The objective was to evaluate a community pharmacist intervention improve adherence with antihypertensive medicines view improving blood pressure (BP) control.prospective, non-blinded, cluster-randomized, controlled trial.adults primary hypertension who obtained in the previous 6 Patients...
Background An infectious disease caused by a novel coronavirus (later called COVID-19) reached pandemic levels in 2020 and community pharmacists were involved responding to this pandemic, also Kosovo. Objectives To explore the experiences of relation provision pharmacy services during COVID-19 pandemic. Setting Community Methods This was cross-sectional study where data collected via self-administered online questionnaire, from 264 actively practicing Kosovo The questionnaire consisted...
We examined cytoplasmic trafficking and nuclear translocation of adeno-associated virus type 2 (AAV) by using Alexa Fluor 488-conjugated wild-type AAV, A20 monoclonal antibody immunocytochemistry, subcellular fractionation techniques followed DNA hybridization. Our results indicated that in the absence adenovirus (Ad), AAV enters cell rapidly escapes from early endosomes with a t(1/2) about 10 min postinfection. Cytoplasmically distributed accumulated around nucleus persisted perinuclearly...
A number of factors have been hypothesized to increase the risk amiodarone-induced pulmonary toxicity (AIPT). This study aimed confirm these and determine whether a cohort tertiary hospital patients diagnosed with AIPT demonstrated comparable characteristics.Phase I this involved compilation database adverse reactions amiodarone reported Australian US drug agencies, identification for using logistic regression analysis. In Phase II, cases were identified via retrospective review medical...
The Internet offers great opportunities for consumers to be informed about their health. However, concerns have been raised regarding its impact on the traditional health consumer-health professional relationship. Our recent survey of 400 Australian adults identified that over half required some form navigational support in locating appropriate Web-based information. We propose provided by professionals would preferred consumers; this preference is regardless whether a need support....
Introduction The repurposing of non-antibiotic drugs as adjuvant antibiotics may help break antimicrobial resistance (AMR). Statins are commonly prescribed worldwide to lower cholesterol. They also possess qualities AMR “breakers”, namely direct antibacterial activity, synergism with antibiotics, and ability stimulate the host immune system. However, statins’ role breakers be limited. Their current extensive use for cardiovascular protection might result in selective pressures resistance,...
Pain is common among people with moderate to severe dementia, but inability of patients self-report means it often goes undetected and untreated. We developed the electronic Assessment Tool (ePAT) address this issue. A point-of-care App, utilizes facial recognition technology detect micro-expressions indicative pain. ePAT also records presence pain-related behaviors under five additional domains (Voice, Movement, Behavior, Activity, Body). In observational study, we assessed psychometric...
Background Infants are unable to self-report their pain, which, therefore, often goes underrecognized and undertreated. Adequate assessment of including procedural which has short- long-term consequences, is critical for its management. The introduction mobile health–based (mHealth) pain tools could address current challenges an area requiring further research. Objective purpose this study evaluate the accuracy feasibility aspects PainChek Infant and, assess applicability in intended...
Object. Achieving distribution of gene-carrying vectors is a major barrier to the clinical application gene therapy. Because blood—brain barrier, genetic central nervous system (CNS) even more challenging than delivery other tissues. Direct intraparenchymal microinfusion, minimally invasive technique, uses bulk flow (convection) distribute suspensions macromolecules widely through extracellular space (convection-enhanced [CED]). Although acute injection into solid tissue often used for...
Background. Pain in dementia is predominant particularly the advanced stages or those who are unable to verbalize. Uncontrolled pain alters course of behaviors patients with making them perturbed, unsettled, and devitalized. Current measures assessing this population group inadequate underutilized clinical practice because they lack systematic evaluation innovative design. Objective. To describe a novel method system assessment using combination technologies: automated facial recognition...
Abstract Background Integration of clinical pharmacists into multidisciplinary Mental Health Hospital-in-the-Home teams is increasing but little known about the medication safety contribution these make. Aim To evaluate whether pharmacist involvement in a service improved key performance indicators. Method Medical records were retrospectively reviewed all patients admitted to 2 Western Australian services from September November 2015. Site 1 was 16-bed incorporating as part its team....