- Thyroid Disorders and Treatments
- Clinical Laboratory Practices and Quality Control
- Hormonal Regulation and Hypertension
- COVID-19 Clinical Research Studies
- Hormonal and reproductive studies
- Colorectal Cancer Screening and Detection
- Growth Hormone and Insulin-like Growth Factors
- Human Health and Disease
- Scientific Measurement and Uncertainty Evaluation
- Analytical Methods in Pharmaceuticals
- Congenital Anomalies and Fetal Surgery
- Infectious Encephalopathies and Encephalitis
- Mosquito-borne diseases and control
- SARS-CoV-2 and COVID-19 Research
- Balkan and Eastern European Studies
- Glycogen Storage Diseases and Myoclonus
- Iron Metabolism and Disorders
- Prostate Cancer Treatment and Research
- Forensic Toxicology and Drug Analysis
- Effects and risks of endocrine disrupting chemicals
- Erythropoietin and Anemia Treatment
- Thyroid and Parathyroid Surgery
- Monoclonal and Polyclonal Antibodies Research
- Pain Mechanisms and Treatments
- Adrenal Hormones and Disorders
University of Osijek
2016-2024
In this study, we present a case of falsely elevated oestradiol (E2) concentration, determined by two immunoassays, in breast cancer patient receiving exemestane therapy. The positive bias immunochemical measurements was revealed using liquid chromatography tandem mass spectrometry which showed undetectable E2 concentration. discrepancy is expected to be consequence the structural resemblance and sharing same steroidal backbone. Inaccurate laboratory findings therapy monitoring, as case, may...
There is a growing amount of evidence showing the significant analytical bias steroid hormone immunoassays, but large number available immunoassays makes conduction single comprehensive study this issue hardly feasible. Aim was to assess six heterogeneous for serum aldosterone, cortisol, dehydroepiandrosterone sulphate (DHEAS), testosterone, 17-hydroxyprogesterone (OHP) and progesterone using liquid chromatography coupled tandem mass spectrometry (LC-MS/MS).This method comparison included 49...
Lumbar radicular pain is a major public health and economic problem. It among the most common reasons for professional disability. The cause of lumbar intervertebral disc herniation, which results from degenerative changes. dominant mechanisms are direct pressure hernia on nerve root local inflammatory process triggered by herniation. Treatment includes conservative, minimally invasive, surgical treatment. number invasive procedures constantly increasing, these methods epidural...
Introduction: The aim was to evaluate the BD Barricor tubes by comparison with Rapid Serum Tubes (RST) through measuring 25 analytes and monitoring sample stability after 24 hours 7 days. Materials methods: Samples of 52 patients from different hospital departments were examined. Blood collected in RST (Becton, Dickinson Company, Franklin Lakes, USA). Analytes measured Beckman Coulter AU 480 (Beckman Coulter, Brea, USA), Dimension EXL (Siemens Healthcare Diagnostics, Newark, USA) ARCHITECT...
Background and objectives. Diet is the crucial environmental factor in sporadic colorectal cancer. Its complexity diversity reflect our cultural historical background, could potentially explain why existing public health strategies focused on cancer are failing. Materials methods. An observational cross-sectional study encompassed 60 non-metastatic CRC patients to assess dietary factors related cancer, with regard their traditional diet i.e. region they come from. Patients were recruited...
This case report describes interference from heterophilic antibodies in D-dimer assay. The was suspected due to discrepancies between concentrations the original sample and diluted samples, as well inconsistent clinical findings. patient's medical history, laboratory results, imaging studies were considered investigation. Heterophilic antibodies, likely developed during SARS-CoV-2 infection, identified probable cause of interference. confirmed through various methods, including dilution...
Background A rare case of coinfection Plasmodium falciparum and SARS-CoV-2 disease in Croatia is presented this report.Methods We tracked epidemiological laboratory findings a patient with coinfection. complete blood count was performed using the Sysmex XN-2000 analyser (Sysmex Corporation, Kobe, Japan), coagulation analyses were BCS XP coagulometer (Siemens Healthineers AG, Erlangen, Germany). Procalcitonin (PCT) Interleukin-6 (IL-6) measured by electrochemiluminescence immunoassay (ECLIA)...
IntroductionLaboratory plays important part in screening, diagnosis, and management of thyroid disorders. The aim this study was to estimate current laboratory preanalytical, analytical postanalytical practices policies Croatia. Materials methodsWorking Group for Laboratory Endocrinology the Croatian Society Medical Biochemistry Medicine designed a questionnaire with 27 questions statements regarding protocols measuring function tests. survey sent 111 medical biochemistry laboratories...
Introduction: Hepcidin-25, the bioactive form of hepcidin, is master protein in regulating iron homeostasis. Serum concentrations, measured by different methods, are often incomparable and complicate results interpretation.Materials Methods: The aim was to verify first fully automated enzyme-linked immunosorbent assay (ELISA) method, using DRG Hybrid XL analyzer (DRG Instruments, Marburg, Germany) standardized against mass spectrometry method. Intra- (CVi) inter-assay (CVg) precision bias...