A5010494808- Forensic Toxicology and Drug Analysis
- Prostate Cancer Treatment and Research
- Environmental Science and Water Management
- Cytokine Signaling Pathways and Interactions
- Acute Kidney Injury Research
- Cancer, Lipids, and Metabolism
- Birth, Development, and Health
- Hormonal and reproductive studies
- Bone health and osteoporosis research
- Sensor Technology and Measurement Systems
- Reproductive Physiology in Livestock
- Adrenal Hormones and Disorders
- Thyroid Disorders and Treatments
- Metabolomics and Mass Spectrometry Studies
- Intensive Care Unit Cognitive Disorders
- Pregnancy and preeclampsia studies
- Analytical Chemistry and Chromatography
- Cardiovascular Disease and Adiposity
- Clinical Laboratory Practices and Quality Control
- Neural dynamics and brain function
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Veterinary Pharmacology and Anesthesia
- Biomarkers in Disease Mechanisms
- Iron Metabolism and Disorders
- Nutritional Studies and Diet
University of Osijek
2013-2024
Klinički bolnički centar Osijek
2012-2024
University of Novi Sad
2023
University of Zagreb
2022
Agricultural Institute Osijek
2012
University of Belgrade
2012
Institute of Public Health Osijek-Baranja County
2006
Background and objectives To investigate the possible effect of postoperatively applied analgesics—epidurally levobupivacaine or intravenously morphine—on systemic inflammatory response plasma concentration interleukin (IL)-6 to determine whether intensity is related postoperative cognitive dysfunction (POCD). Methods This a randomized, prospective, controlled study in an academic hospital. Patients were 65 years older scheduled for femoral fracture fixation from July 2016 September 2017....
In this study, we present a case of falsely elevated oestradiol (E2) concentration, determined by two immunoassays, in breast cancer patient receiving exemestane therapy. The positive bias immunochemical measurements was revealed using liquid chromatography tandem mass spectrometry which showed undetectable E2 concentration. discrepancy is expected to be consequence the structural resemblance and sharing same steroidal backbone. Inaccurate laboratory findings therapy monitoring, as case, may...
There is a growing amount of evidence showing the significant analytical bias steroid hormone immunoassays, but large number available immunoassays makes conduction single comprehensive study this issue hardly feasible. Aim was to assess six heterogeneous for serum aldosterone, cortisol, dehydroepiandrosterone sulphate (DHEAS), testosterone, 17-hydroxyprogesterone (OHP) and progesterone using liquid chromatography coupled tandem mass spectrometry (LC-MS/MS).This method comparison included 49...
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein secreted by activated neutrophils and certain tissues. The aim of this study was to investigate the prognostic role urinary neutrophil (uNGAL) in hospitalized COVID-19 patients with regard mortality. prospective observational cohort involved 86 adult patients. Patients’ urine samples were collected upon admission 48–72 h after admission. General anamnesis clinical status information obtained from medical records. Within 24 sample...
Growth differentiation factor 15 (GDF-15) is a stress-induced cytokine associated with acute and chronic inflammatory states. This prospective observational study aimed to investigate the prognostic roles of GDF-15 routine clinical laboratory parameters in COVID-19 patients. Upon admission 95 adult hospitalized patients Croatia, blood analysis was performed, medical data were collected. The categorized based on survival, ICU admission, hospitalization duration. Logistic regression ROC curve...
Acute pyelonephritis is a severe disease which sometimes difficult to recognize based on clinical symptoms and routinely available diagnostic tests, especially in young children. The aim of this study was assess the value urinary neutrophil gelatinase-associated lipocalin (uNGAL) as biomarker acute pyelonephritis.In case-control we analyzed 134 children (median age 2.5 years) who were admitted Pediatric Clinic University Hospital Centre Osijek, Croatia. Eighty them had pyelonephritis, while...
Carbohydrate sulfotransferases (CHST) were shown to be involved in carcinogenesis. The aim of the study was assess diagnostic value serum CHST7 concentration differentiation between lung cancer and non-malignant pulmonary inflammations.Clinical case-control involving 125 participants conducted: control group containing cases pneumonia chronic obstructive disease compared composed primary metastatic cancers. Serum concentrations routinely used markers including carcinoembryonic antigen (CEA),...
Background: One of the major challenges in improving sepsis care is early prediction complications. The endocannabinoid system has been intensely studied recent years; however, little known about its role humans. This study aimed to assess prognostic endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), as predictors mortality, invasive mechanical ventilation (IMV) requirement, length stay (LOS) patients with sepsis. Materials Methods: In total, 106 confirmed were enrolled...
<p><strong>Aim<br /></strong> To investigate a potential of the clinical use soluble fms-like tyrosine kinase 1 (sFLT-1) to placental growth factor (PlGF) ratio from perspective small hospital centre. <br /><strong>Methods<br Maternal serum samples were analysed at 24 1/7-28 0/7 , and 28 1/7-32 weeks gestation. The level sFLT-1 PIGF was determined by immunoassay platform used calculate sFLT-1/PIGF in...
The objective was to determine the impact of VKORC1 polymorphisms on warfarin anticoagulant therapy (stable maintenance dose, time required reach therapeutic dose and spent in range) its adverse events (overanticoagulation bleeding events, first overanticoagulation or event, for events) Croatian patients.Blood samples were collected from 186 patients stable therapy.VKORC1 1173C>T â1639G>A gene analyzed using real-time PCR. Prothrombin international normalized ratio (INR) values determined...
Introduction: The aim was to evaluate the BD Barricor tubes by comparison with Rapid Serum Tubes (RST) through measuring 25 analytes and monitoring sample stability after 24 hours 7 days. Materials methods: Samples of 52 patients from different hospital departments were examined. Blood collected in RST (Becton, Dickinson Company, Franklin Lakes, USA). Analytes measured Beckman Coulter AU 480 (Beckman Coulter, Brea, USA), Dimension EXL (Siemens Healthcare Diagnostics, Newark, USA) ARCHITECT...
The aim of the present study was to determine acid-base balance in blood Lacaune sheep during different lactation stages. Thirty lactating were involved research, and monitored early (day 60), medium 120), late stages 180). following parameters determined plasma: pH, partial pressure carbon dioxide – pCO2, oxygen pO2, total tCO2, saturation sO2, actual base excess Cbase B, standard Ecf electrolytes (Na+, K+, Ca2+, Cl- HCO3- bicarbonate), while proteins TP albumin ALB serum. Also, strong ion...
Background and objectives. Diet is the crucial environmental factor in sporadic colorectal cancer. Its complexity diversity reflect our cultural historical background, could potentially explain why existing public health strategies focused on cancer are failing. Materials methods. An observational cross-sectional study encompassed 60 non-metastatic CRC patients to assess dietary factors related cancer, with regard their traditional diet i.e. region they come from. Patients were recruited...
U ovom radu prikazana je realizacija sistema čija uloga merenje faznog stava dva prostoperiodična signala upotrebom tajmerskih modula. razmatrano prostoperiodičnih sa dvokanalnog izvora struje i napona. okviru izlaznog stepena razmatranog javlja se degradacija na kanala izvora, te potrebno izvršiti korekciju stava. Potreba za vršenjem korekcije zahteva poznavanje zadatog ulazu precizno izlazu izvora. Metoda merenja u zasniva merenju vremenskog smicanja signala, osnovu koga određuje vrednost...