A5036488568- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Tracheal and airway disorders
- Herpesvirus Infections and Treatments
- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Vector-Borne Animal Diseases
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Clostridium difficile and Clostridium perfringens research
- Respiratory and Cough-Related Research
- Parvovirus B19 Infection Studies
- Cystic Fibrosis Research Advances
- Viral Infections and Outbreaks Research
- Emergency and Acute Care Studies
- Pediatric health and respiratory diseases
- Viral Infections and Vectors
- HIV Research and Treatment
- Cytomegalovirus and herpesvirus research
- HIV/AIDS Research and Interventions
- Drug-Induced Adverse Reactions
- Amyloidosis: Diagnosis, Treatment, Outcomes
Centre hospitalier universitaire de Québec
1998-2023
Université Laval
1991-2023
Centre hospitalier de l'Université Laval
1997-2022
Communication, Information, Médias
2019
Animal, Santé, Territoires, Risques et Ecosystèmes
2018-2019
Centre de Coopération Internationale en Recherche Agronomique pour le Développement
2018-2019
Université de Montpellier
2019
Ministère de l'Agriculture
2019
University of Ottawa
2017
Public Health Agency of Canada
2016
A third serotype of human parechovirus (HPeV) has been recently isolated from stool specimens a young Japanese child with transient paralysis. We report 3 additional cases neonatal sepsis caused by HPeV-3 in the fall 2001 Canadian infants 7-27 days old. All children were hospitalized high fever, erythematous rash, and tachypnea for median 5 days. The viruses nasopharyngeal aspirates grew slowly on tertiary monkey kidney cells successfully passaged Vero cells. predicted amino acid identity...
Background: Vaccine hesitancy (VH) is a growing problem. The first step in addressing VH to have an understanding of who are the hesitant individuals and what their specific concerns. aim this survey was assess mothers’ level vaccine vaccination knowledge, attitudes, beliefs.Methods: Mothers newly-born infants four maternity wards Quebec (Canada) completed self-administered questionnaire. questionnaire included items intention vaccinate. scores were calculated using Parents Attitudes about...
We obtained specimens for viral culture from mothers, infants, or both at the time of 6904 deliveries, without regard to mothers' history genital herpes. Herpes simplex virus (HSV) was recovered in cultured 14 deliveries (0.20 percent); all mothers were asymptomatic. All isolates herpes type 2 (HSV-2). Only 1 women (7 percent) had a herpes, whereas 12 (86 serologic evidence previous infection with HSV-2. None infants born these contracted neonatal However, one two primary HSV delivery Our...
Objective. Although universal immunization against Bordetella pertussis (whooping cough) infection has resulted in dramatic reductions the incidence of pertussis, outbreaks continue to occur countries with excellent vaccine coverage. Treatment may ameliorate symptom severity during catarrhal phase but no effect on established paroxysms, emesis, or apnea if given paroxysmal convalescent phases. Erythromycin, recommended for treatment prevent transmission infection, is poorly tolerated because...
BackgroundMany countries are grappling with growing numbers of parents who delay or refuse recommended vaccinations for their children. This has created a need strategies to address vaccine hesitancy (VH) and better support parental decision-making regarding vaccination.AimTo assess vaccination intention (VI) VH among received an individual motivational-interview (MI) based intervention on infant immunisation during post-partum stay at maternity ward between March 2014 February...
To determine the relationship between receipt of aerosolized ribavirin and hospital course high-risk infants children with respiratory syncytial virus (RSV) lower infection (LRI).The 1993-1994 Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) RSV database consists prospectively enrolled acute LRI, admitted to nine Canadian pediatric tertiary care centers. After excluding cases compromised immunity and/or nosocomial infection, subsets any congenital heart disease...
In order to study the epidemiology of herpes simplex type 2 (HSV-2) infections during pregnancy, we used an enzyme immunoassay detect type-specific antibodies HSV-2 glycoprotein G in serial blood samples obtained from a cohort 1891 pregnant women. Blood at about 17 and 32 weeks gestation time delivery were assessed for antibody evaluate prevalence past with rate acquisition infection pregnancy. Three hundred eleven women (16.5%) found have had HSV-2. Four 1580 who initially seronegative...
Objective. To determine the effects of age and respiratory syncytial virus (RSV) antibody status on frequency severity RSV infections in children with underlying heart or lung disease. Design. Cohort study conducted during two consecutive seasons. Setting. Ambulatory patients at eight Canadian pediatric tertiary care centers. Methods. Subjects under 3 years old disease who were digoxin-dependent had not received corrective cardiac surgery enrolled. Demographic information an acute sera for...
In a multicenter, randomized, placebo-controlled clinical trial of pertussis immune globulin, intravenous (P-IGIV), 25 infants hospitalized with were enrolled in 24 months (15% the target sample size) before study was prematurely terminated because expiration P-IGIV lots and unavailability additional product. Although well tolerated, there no difference number or rate improvement symptoms (paroxysmal cough, whoop, apnea, bradycardia, oxygen desaturations) recipients compared placebo.
One of the main determinants public immunization success is health professionals' support and recommendations. Little known about physicians' level intentions regarding A(H1N1) pandemic influenza vaccination. The aim this survey was to document Canadian family paediatricians' knowledge, attitudes practices (KAP) as well their vaccines right before beginning largest campaign in history.A self-administered, anonymous, mail-based questionnaire sent a random sample physicians all paediatricians...
OBJECTIVE: Young children are generally considered immunologically naive with respect to influenza exposure opportunities; thus, a 2-dose schedule is recommended when child first immunized conventional vaccine lacking adjuvant. We estimated the effectiveness of single pediatric dose AS03-adjuvanted against hospitalization for confirmed pandemic A/H1N1 (pH1N1) infection in aged 6 months 9 years during fall 2009 vaccination campaign. METHODS: In matched case-control design, case subjects were...
Randomized trials of ribavirin therapy have used clinical scores to assess illness severity. Little information on agreement for these findings between observers has been published. We decided determine interobserver (1) a history apnea or respiratory failure; (2) assessment cyanosis, rate, retractions, and oximetry; (3) determination reason hospitalization (requirement medications, supportive care, underlying illness, poor home environment). At eight centers 137 RSV-infected patients were...
For patients who have experienced adverse events following immunization (AEFI) or specific medical conditions, there is limited evidence regarding the best approach to immunization. The Special Immunization Clinics (SICs) Network was established standardize patient management and assess outcomes after reimmunization. study objective describe first 2 years of network's implementation.Twelve SICs were across Canada by infectious diseases specialists allergists. Inclusion criteria as follows:...
Given the improved efficacy of nasal live-attenuated influenza virus vaccine (LAIV) compared with injectable in children, we aimed to determine its safety individuals cystic fibrosis (CF).A cohort 168 study participants, aged 2 18 years CF, vaccinated LAIV between October 1, 2012, and January 30, 2013, was followed prospectively for 56 days after initial vaccination 3 pediatric CF clinics across province Quebec. Days 0 28 post-LAIV were considered at-risk period all outcomes interest, 29...