A5033307633- Ferroelectric and Piezoelectric Materials
- Multiferroics and related materials
- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Antimicrobial Resistance in Staphylococcus
- Respiratory viral infections research
- Dielectric properties of ceramics
- Glioma Diagnosis and Treatment
- Viral gastroenteritis research and epidemiology
- Tuberculosis Research and Epidemiology
- Cancer Diagnosis and Treatment
- Antifungal resistance and susceptibility
- Microwave Dielectric Ceramics Synthesis
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Streptococcal Infections and Treatments
- Brain Metastases and Treatment
- Vibrio bacteria research studies
- Listeria monocytogenes in Food Safety
- Immunodeficiency and Autoimmune Disorders
- Fungal Biology and Applications
- Multiple and Secondary Primary Cancers
- Dental Research and COVID-19
- Ferroelectric and Negative Capacitance Devices
Gujarat Cancer & Research Institute
2022-2024
Banaras Hindu University
2023
Indian Institute of Technology BHU
2023
Baidya and Banskota Hospital
2019-2023
NIMS University
2023
Patan Hospital
2013-2021
Patan Academy of Health Sciences
2013-2020
Background Salmonella serovars Typhi (S. Typhi) and Paratyphi A A), the causative agents of enteric fever, have been routinely isolated organisms from blood febrile patients in Kathmandu Valley since early 1990s. Susceptibility against commonly used antimicrobials for treating fever has gradually changed throughout South Asia this time, posing serious treatment challenges. Here, we aimed to longitudinally describe trends isolation enterica assess changes their antimicrobial susceptibility...
Abstract Background Multi-drug resistance (MDR) and extensive-drug (XDR) associated with extended-spectrum beta-lactamases (ESBLs) carbapenemases in Gram-negative bacteria are global public health concerns. Data on circulating antimicrobial (AMR) genes their correlation MDR ESBL phenotypes from Nepal is scarce. Methods A retrospective study was performed investigating the distribution of carbapenemase potential association E. coli , Klebsiella spp., Enterobacter spp. Acinetobacter isolated a...
The GeneXpert MTB/RIF assay (Xpert) is a novel automated diagnostic tool for tuberculosis but its optimal placement in the healthcare system has not been determined. objective of this study was to determine possibility additional case detection pulmonary (PTB) by offering Xpert smear-negative patients low-HIV burden setting with no Mycobacterium ( M.tb. ) culture facilities. Patients routinely presenting symptoms suggestive PTB negative smears were offered single test on fee-paying basis....
Background. Diabetic patients are more susceptible to urinary tract infection compared nondiabetic patients, Escherichia coli being the most common uropathogen causing UTI. Unreasonable and incorrect antibiotic prescription for UTI in these may induce development of antibiotic-resistant pathogens resulting delayed recovery longer hospitalization. In addition these, biofilm forming capacity pathogen worsen problem. The main aim this cross-sectional study (conducted from March September 2015)...
In Nepal, Streptococcus pneumoniae (pneumococcus) is a common cause of bacterial pneumonia in children, and major health concern. There are few data on the effect vaccination disease or colonisation with pneumococci nasopharynx children this setting. The 10-valent pneumococcal conjugate vaccine (PCV10) was introduced into routine infant immunisation schedule Nepal 2015. We aimed to investigate introduction PCV10 carriage Nepal.We did an observational cohort study Nepal. hospital surveillance...
Background In many rural areas at risk for enteric fever, there are few data on Salmonella enterica serotypes Typhi (S. Typhi) and Paratyphi Paratyphi) incidence, due to limited laboratory capacity microbiologic culture. Here, we describe an approach that permits recovery of the causative agents fever in such settings. This involves use electricity-free incubator based upon phase-change materials. We compared this against conventional blood culture detection typhoidal Salmonella....
A comprehensive longitudinal understanding of the changing epidemiology agents causing bacteraemia and their AMR profiles in key locations is crucial for assessing progression magnitude global crisis. We performed a retrospective analysis routine microbiological data from April 1992 to December 2014, studying time trends non-Salmonella associated at single Kathmandu healthcare facility. The distribution aetiological agents, antimicrobial susceptibility profiles, hospital ward isolation were...
Exploring the functionalities of materials requires a profound understanding crystal structure. In this paper, room temperature structures new solid solution (1 - x)Ba(Cu1/3Nb2/3)O3-(x)PbTiO3 have been investigated in entire compositional span and different crystallographic phases phase coexistence regions discovered. The confirmation symmetry these has done with help Rietveld analysis high-resolution XRD data. Despite both end components, Ba(Cu1/3Nb2/3)O3 PbTiO3, having tetragonal (P4mm)...
Background: There is a high risk of occupational exposure to tuberculosis among healthcare workers in endemic countries. Regular screening for not carried out Nepal. Infection control measures are also routinely implemented. The aim this study was determine the prevalence active staff/students at Patan Hospital.Methods: Participants were given self-administered questionnaire and invited undergo chest radiography. Cases scored reviewed based on predetermined criteria, presumptive cases sputum...
Invasive bacterial disease (IBD; including pneumonia, meningitis, sepsis) is a major cause of morbidity and mortality in children low-income countries.We analyzed data from surveillance study suspected community-acquired IBD <15 years age Kathmandu, Nepal, 2005 to 2013 before introduction pneumococcal conjugate vaccines (PCV). We detailed the serotype-specific distribution invasive (IPD) incorporated antigen PCR testing cerebrospinal fluid (CSF) with meningitis.Enhanced was undertaken during...
Background: Staphylococci are posing threat due to increasing trend of antimicrobial resistance particularly methicillin. Macrolide lincosamide streptogramin B (MLSB) family antibiotics is commonly used treat such infections. This study was aimed determine the prevalence inducible clindamycin and observation erm msr genes among isolated from tertiary care hospital Nepal during July 2017 March 2018.Methods: different clinical specimens were identified antibiotic susceptibility profile...
Introduction: A 41‐year‐old man with a history of alcoholic cirrhosis presented to Patan Hospital in Kathmandu, Nepal, severe headache. Case presentation: Clinical examination found an isolated sixth nerve palsy the left side normal blood parameters and brain scan. An initial cerebrospinal fluid analysis lymphocytosis, significantly elevated protein level reduced glucose. Tubercular meningitis was considered; however, patient did not improve re‐examination confirmed cryptococcal meningitis....
New diagnostic tests for the aetiology of childhood pneumonia are needed. We evaluated antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a potential test pneumococcal pneumonia. enrolled 348 children with admitted Patan Hospital, Kathmandu, Nepal between December 2015 and September 2016. PBMCs sampled participants were incubated 48 h before harvesting culture (ALS). used...
<title>Abstract</title> Purpose The purpose of this study was to assess the feasibility and efficacy helical intensity-modulated radiation therapy (IMRT) for Craniospinal Irradiation (CSI) on tomotherapy, aiming enhance target coverage while minimizing dose nearby organs at risk (OARs) acute toxicities. Methods It a prospective observational single-arm study, 24 patients meeting inclusion criteria were enrolled, with most common histology being medulloblastoma. Planning executed using...
Objectives: To determine the prevalence of Gram-negative bacteria in lower respiratory tract infections and study biofilm producing Pseudomonas aeruginosa. Methods: This was conducted at B & Hospital Pvt. Ltd., Lalitpur, Nepal from February to September 2018. The samples were collected patients (n=420) with signs symptoms suggestive LRTIs. isolated organisms identified antimicrobial sensitivity performed. Among all isolates, P. aeruginosa isolates subjected for detection by microtitre...
The study presents the significance of Remote Sensing (RS) and Geographical Information System (GIS) in providing accurate assessment environmental changes due to rapid pace industrialization Sanand. To illustrate inherent inter-disciplinary nature (GIS), a Environmental Impact Assessment (EIA) using GIS is presented this paper. environment issues dealt with relate archaeology, land use, transport, water bodies, geology. increasing damage caused by activity closely associated level economic...
Abstract Background Staphylococci are the most commonly isolated pathogen from clinical specimen. These isolates posing threat due to increasing trend of antimicrobial resistance particularly methicillin. Macrolide-lincosamide streptogramin B family antibiotics is used treat such infections. This study was aimed detect prevalence inducible clindamycin and observation erm msr genes among tertiary care hospital Nepal.Methods different specimen were identified antibiotic susceptibility profile...