A5101704709- melanin and skin pigmentation
- Cancer Mechanisms and Therapy
- Histone Deacetylase Inhibitors Research
- Protein Degradation and Inhibitors
- Skin Protection and Aging
- Herpesvirus Infections and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Flavonoids in Medical Research
- Genomics, phytochemicals, and oxidative stress
- Cancer Research and Treatments
- Cardiovascular Function and Risk Factors
- Heme Oxygenase-1 and Carbon Monoxide
- Traditional Chinese Medicine Analysis
- T-cell and B-cell Immunology
- Silk-based biomaterials and applications
- Gut microbiota and health
- Infective Endocarditis Diagnosis and Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Ferroptosis and cancer prognosis
- Cardiac Structural Anomalies and Repair
- Peptidase Inhibition and Analysis
- Sexual function and dysfunction studies
University of Hong Kong
2023-2025
Jilin University
2020-2024
University of Helsinki
2023
Tianjin Nankai Hospital
2016-2023
Marine Design & Research Institute of China
2022
Civil Aviation Administration of China
2022
Nanjing University of Information Science and Technology
2022
Tianshui Normal University
2022
Third People's Hospital of Hangzhou
2006-2021
Shanghai Jiao Tong University
2020
Although the infant gut microbiota has been extensively studied, comprehensive assessment on determinants including technical variables not performed in large cohorts.
Background Genetic factors are thought to be involved in the development of vitiligo. Aim To explore possible genetic model vitiligo by analyzing characteristics 815 patients and their families from south China (Zhejiang Province). Methods Data for with were obtained questionnaire. The inheritance pattern estimation, heritability calculation, complex segregation analysis performed using Penrose method, Falconer regression SAGE-REGTL program, respectively. Results In probands, 128 (15.7%) had...
Vitiligo is an acquired skin disorder with great social impact. It can be successfully treated using cultured autologous melanocytes transplantation.To evaluate the effect of different modalities narrow-band ultraviolet B (NB-UVB) therapy on outcome melanocyte transplantation in treating vitiligo.Patients undergoing were randomly assigned to four study groups. Group 1 underwent 20 sessions NB-UVB treatment before transplantation; 2 30 after 3 and 4 only transplantation.Four hundred...
The role of hepatic resection in hepatocellular carcinoma (HCC) with accompanying portal vein tumor thrombus (PVTT) remains controversial. This study aimed to evaluate the surgical outcomes compared those transarterial chemoembolization (TACE) HCC patients. A retrospective was conducted using medical records 230 patients invasion who underwent (96 patients) or TACE (134 patients). baseline characteristics, clinicopathological parameters, and overall survival rates were between 2 groups....
ABSTRACT Most bats are insectivorous, but some species have evolved the ability to prey on fish. Although piscivory has been confirmed in Rickett's big‐footed myotis ( Myotis pilosus ), extent of other cohabiting is uncertain. This study aims explore dietary niches and fish consumption three a subtropical East Asian region, specifically diet M. . Our findings reveal, for first time, that consumes marine fishes, contrast previous research conducted inland regions suggested year‐round...
Vitiligo is an acquired, pigmentary skin disorder which disfiguring and difficult to treat. Phototherapy application of topical corticosteroids are most commonly prescribed. However, these therapies often not effective use on the face may lead cutaneous atrophy, telangiectasia, ocular complications.We sought assess efficacy tacrolimus ointment in treatment vitiligo.A prospective pilot study was performed 30 patients with vitiligo. Patients were treated for at least 4 months. Clinical...
Objectives: To compare the efficacy of blister roof grafting (BG), cultured melanocytes transplantation (CMT) and non-cultured epidermal cell suspension (NCES) in treatment stable vitiligo. Methods: In each person 83 vitiligo patients one macule was selected divided three areas for separate with BG, CMT NCES same session. The results were evaluated 12-month post-surgery extent repigmentation color match. Results: A satisfactory result (>50% repigmentation) achieved 92%, 82% 81% methods,...
Glioma stem cells (GSC) are essential for tumor maintenance, invasiveness, and recurrence. Using a global epigenetic screening with an shRNA library, we identified HDAC3 as factor GSC stemness. Here, demonstrated that GSCs poorly respond to inhibitor, RGFP966 (HDAC3i), owing the production of IL6 STAT3 activation. To enhance sensitivity HDAC3i, explored whether cotreatment BRD4 JQ1 (BRD4i), in produced better antitumor effect. BRD4i synergistically inhibits growth association HDAC3i....
Forkhead box (FOX)K2 (FOXK2) is a member of the FOX transcription factor family. It has been suggested previously that FOXK2 required to suppress tumor growth; however, exact role in gastric cancer remains be elucidated. In present study, association between expression and clinicopathological characteristics patients with was investigated. The prognostic value significance parameters overall survival (OS) progression‑free were also determined by analysis. To investigate functional roles...
Autologous non-cultured melanocyte-keratinocyte transplantation (MKTP) can be used to treat stable vitiligo cases, but there were insufficient clinical data evaluate its safety and efficacy.To assess the influence of various factors on therapeutic outcome MKTP.The single-center retrospective study included patients who underwent MKTP between June 2009 2018. Univariate and/or multivariable analysis determine affecting repigmentation.The comprised 2283 had long-term follow-up (12-108months)....
To compare the outcomes of hepatic resection and transarterial chemoembolization (TACE) for solitary hepatocellular carcinoma (HCC) according to Barcelona Clinic Liver Cancer (BCLC) staging system.A consecutive sample 540 patients with HCC who underwent liver (n = 312) or TACE 128) were included in present study. Baseline characteristics, tumor post-operative complications compared between two groups. The Kaplan-Meier method was used long-term survival analysis. Independent prognostic...
Nonablative laser has been used for the treatment and prevention of skin aging many years. Although mechanism not elucidated, histological evaluation showed that dermal fibroblasts its collagen production should be main target this rejuvenation. In order to determine effects a 1320 nm nonablative on human fibroblasts, two secretion factors, basic fibroblast growth factor (bFGF) transforming β1(TGF-β1), in vitro were detected.The cultured irradiated with at dose 15, 20, 24 J/cm(2)...