Chen Wang

ORCID: 0000-0003-0084-496X
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About
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Research Areas
  • Guidance and Control Systems
  • Quantum chaos and dynamical systems
  • Adaptive Control of Nonlinear Systems
  • CRISPR and Genetic Engineering
  • Computational Fluid Dynamics and Aerodynamics
  • Distributed Control Multi-Agent Systems
  • Genomics and Rare Diseases
  • RNA Research and Splicing
  • Advanced SAR Imaging Techniques
  • Marine and coastal ecosystems
  • Adsorption and Cooling Systems
  • Target Tracking and Data Fusion in Sensor Networks
  • Congenital heart defects research
  • Hepatitis Viruses Studies and Epidemiology
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Aerodynamics and Fluid Dynamics Research
  • Liver Disease and Transplantation
  • Turbomachinery Performance and Optimization
  • Robotic Path Planning Algorithms
  • Wastewater Treatment and Nitrogen Removal
  • Hepatitis B Virus Studies
  • Genetics and Neurodevelopmental Disorders
  • Electromagnetic Launch and Propulsion Technology
  • Nuclear Structure and Function

Chinese PLA General Hospital
2024

302 Military Hospital of China
2024

Jiangsu Food and Pharmaceutical Science College
2024

Southern University of Science and Technology
2019-2024

Chinese University of Hong Kong
2022-2023

Peking University
2022

State Key Laboratory of Turbulence and Complex Systems
2022

University of Hong Kong
2021

Nanjing University of Science and Technology
2021

Hong Kong Baptist University
2019

We study pursuit-evasion differential games between a faster pursuer moving in 3D space and an evader plane. first extend the well-known Apollonius circle to space, by which we construct isochron for considered two players. Then both cases with without static target are corresponding optimal strategies derived using concept of isochron. In order guarantee optimality proposed strategies, value functions given further proved be solution Hamilton-Jacobi-Isaacs equation. Simulations comparison...

10.23919/acc53348.2022.9867329 article EN 2022 American Control Conference (ACC) 2022-06-08

Single gene disorders are individually rare but collectively common leading causes of neonatal and pediatric morbidity mortality. Both parents or the mothers affected individuals with autosomal recessive X-linked diseases, respectively, carrier(s). Carrier frequencies diseases can vary drastically among different ethnicities. This study established a robust pipeline for estimating ranking carrier all known 2699 genes based on genome-wide sequencing data in healthy individuals. The discovery...

10.1038/s41525-022-00344-7 article EN cc-by npj Genomic Medicine 2022-12-19

This paper studies a novel encirclement guaranteed cooperative pursuit problem involving N pursuers and single evader in an unbounded two-dimensional game domain. Throughout the game, are required to maintain of evader, i.e., should always stay inside convex hull generated by all pursuers, addition achieving classical capture condition. To tackle this challenging problem, robust model predictive control (RMPC) based formulation framework is first introduced, which simultaneously accounts for...

10.1109/iros51168.2021.9636127 article EN 2021 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) 2021-09-27

<title>Abstract</title> Background/Aims: Organ transplant recipients with hepatitis E virus (HEV) infection bears high risk to develop chronic hepatitis, which is generally associated immunosuppressive therapies. This study aimed identify the incidence and predictors of <italic>de novo</italic> HEV in patients after receiving transplantation. Methods We performed a large retrospective investigate prevalence anti-HEV at baseline, transplantation, factors among liver China. A total 407 were...

10.21203/rs.3.rs-4023335/v1 preprint EN cc-by Research Square (Research Square) 2024-04-11

Functional cure for chronic hepatitis B (CHB) remains challenging due to the lack of direct intervention methods hepatic inflammation. Multi-omics research offers a promising approach understand inflammation mechanisms in CHB. A Bayesian linear model linked gene expression with clinical parameters, and population-specific analysis (PSEA) refined bulk into specific cell types across different phases. These models were integrated our key factors like inflammatory cells, immune activation, T...

10.1002/imt2.221 article EN cc-by iMeta 2024-07-04

The target angular glint is the main factor restricting tracking accuracy of radar at close range. There are few researches on pulse compression radar. Here, model large aerodynamic under proposed. field measured data verify validity model. Second, a frequency-diversity algorithm based gating weighting proposed to suppress glint. Simulation results show that its performance better than traditional frequency diversity algorithm. Third, influence total hopping bandwidth and number discussed....

10.1049/joe.2019.0618 article EN cc-by The Journal of Engineering 2019-09-23

A pursuit-evasion differential game with two faster pursuers in 3D space and one slower evader a 2D plane is studied. Two pursuers, which have different speeds, attempt to cooperate capture the while struggles avoid or delay capture. Using games concept of isochron, we present complete solution this develop optimal strategies for both evader. In order guarantee optimality proposed strategies, value function given further proved be corresponding Hamilton-Jacobi-Isaacs equation. Finally,...

10.23919/ccc55666.2022.9902586 article EN 2022 41st Chinese Control Conference (CCC) 2022-07-25

Abstract Rotation-isolating rudder is a type of correction mechanism widely used in two-dimensional trajectory projectile. In this paper, we focus on its attitude servo system, develop disturbance-observer-based sliding-mode control method, and prove the asymptotic stability method. Based single-axis turntable established, test rolling performance rotation-isolating rudder, experimental result shows effectiveness method developed.

10.1088/1742-6596/1848/1/012119 article EN Journal of Physics Conference Series 2021-04-01

Abstract DExD/H-box RNA helicases (DDX/DHX) are encoded by a large paralogous gene family; in subset of these human helicase genes, pathogenic variation causes neurodevelopmental disorder (NDD) traits and cancer. DHX9 encodes BRCA1-interacting nuclear regulating transcription, R-loops, homologous recombination exhibits the highest mutational constraint all DDX/DHX paralogs but remains without disease trait associations. Using exome sequencing family-based rare variant analysis, we identified...

10.1101/2023.03.01.23286475 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2023-03-05

We study pursuit-evasion differential games between a faster pursuer moving in 3D space and an evader plane. first extend the well-known Apollonius circle to space, by which we construct isochron for considered two players. Then both cases with without static target are corresponding optimal strategies derived using concept of isochron. In order guarantee optimality proposed strategies, value functions given further proved be solution Hamilton-Jacobi-Isaacs equation. Simulations comparison...

10.48550/arxiv.2202.13522 preprint EN other-oa arXiv (Cornell University) 2022-01-01

This paper studies a novel encirclement guaranteed cooperative pursuit problem involving $N$ pursuers and single evader in an unbounded two-dimensional game domain. Throughout the game, are required to maintain of evader, i.e., should always stay inside convex hull generated by all pursuers, addition achieving classical capture condition. To tackle this challenging problem, robust model predictive control (RMPC) based formulation framework is first introduced, which simultaneously accounts...

10.48550/arxiv.2108.07445 preprint EN other-oa arXiv (Cornell University) 2021-01-01

This study focuses on reachability problems in differential games. An improved level set method for computing reachable tubes is proposed this paper. The tube described as a sublevel of value function, which the viscosity solution Hamilton-Jacobi equation with running cost. We generalize concept and propose new class tubes, are referred to cost-limited one. In particular, performance index can be specified system, initial states system's trajectories that reach target before increases given...

10.48550/arxiv.2101.09646 preprint EN other-oa arXiv (Cornell University) 2021-01-01
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