Guangyou Chen

ORCID: 0000-0003-0090-8003
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About
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Research Areas
  • Fungal Plant Pathogen Control
  • Plant Pathogens and Fungal Diseases
  • Synthesis and Biological Evaluation
  • Cholinesterase and Neurodegenerative Diseases
  • Growth and nutrition in plants
  • Phytochemical compounds biological activities
  • Antimicrobial agents and applications
  • Insect Resistance and Genetics
  • Polydiacetylene-based materials and applications
  • Environmental Toxicology and Ecotoxicology
  • Plant Molecular Biology Research
  • Plant Disease Resistance and Genetics
  • Seed Germination and Physiology
  • Light effects on plants
  • Plant Stress Responses and Tolerance
  • Click Chemistry and Applications
  • Ubiquitin and proteasome pathways
  • Cancer Research and Treatments
  • Antimicrobial Peptides and Activities
  • Pesticide Exposure and Toxicity
  • Viral Infectious Diseases and Gene Expression in Insects
  • Photosynthetic Processes and Mechanisms
  • Plant-Microbe Interactions and Immunity
  • RNA modifications and cancer
  • Insect and Pesticide Research

Northwest A&F University
2014-2024

Southwest Medical University
2023

Sichuan Agricultural University
2021

Ministry of Education of the People's Republic of China
2014

Osteosarcoma is the most malignant and common primary bone tumor with a high rate of recurrence that mainly occurs in children young adults. Therefore, it vital to facilitate development novel effective therapeutic means improve overall prognosis osteosarcoma patients via deeper understanding mechanisms chemoresistance progression.In this research, relationship between ITGB3 clinical characteristics was detected through analysis publicly available datasets. The expression collected human...

10.1002/cam4.5585 article EN cc-by Cancer Medicine 2023-02-11

The discovery of agricultural fungicide candidates from natural products is one the key strategies for developing environment friendly fungicides with high efficiency, selectivity and unique modes-of-action. Based on previous work, a series novel α-methylene-γ-butyrolactone (MBL) derivatives containing benzothiophene moiety were designed synthesized.

10.1002/ps.8080 article EN Pest Management Science 2024-03-14

Developing fungicides from active botanical skeletons is one of the effective methods to tackle resistance plant pathogens. Based on our previous discoveries, a series novel α-methylene-γ-butyrolactone (MBL) derivatives containing heterocycles and phenyl rings were designed according antifungal molecule carabrone first discovered in Carpesium macrocephalum. The target compounds synthesized, inhibitory activity against pathogenic fungi as well mechanism action then systematically...

10.1021/acs.jafc.3c02117 article EN Journal of Agricultural and Food Chemistry 2023-07-11

Eighteen novel benzamidine derivatives containing 1,2,3-triazole moieties were synthesized. The in vitro and vivo fungicidal acitivities of the title compounds arylamidine intermediates against Colletotrichum lagenarium Botrytis cinerea tested. synthesized benzamidines exhibited weak antifungal activities tested fungi, but some showed excellent to same strains. Among tested, 9b 79% efficacy C. at a concentration 200 μg/mL, compound 16d (90%) toward strain was even superior than that...

10.3390/molecules19055674 article EN cc-by Molecules 2014-05-02

Drought stress (DS) is one of the main abiotic negative factors for plants. Phthalanilic acid (PPA), as a plant growth regulator, can promote and development crops. In order to evaluate ideal application concentration frequency PPA-induced drought resistance in pepper ( Capsicum annuum ) seedlings, PPA was 133.3 mg·L −1 ; 200.0 266.7 , some key indicators were investigated, including leaf wilting index (LWI), relative water content (RWC), malondialdehyde (MDA). We found that LWI RWC...

10.3389/fpls.2023.1156276 article EN cc-by Frontiers in Plant Science 2023-09-27

Hübner (Lepidoptera: Noctuidae) is a globally devastating pest and has evolved with varying levels of resistance to broader spectrum insecticides. CarEs are major enzymes involved in insecticide detoxification metabolic resistance. Four

10.1021/acs.jafc.4c07451 article EN Journal of Agricultural and Food Chemistry 2024-11-07

In order to develop novel, efficient and green fungicides, a series of novel isoaurone derivatives were designed synthesized, which characterized by 1H 13C NMR, high‐resolution mass spectra melting points. The target compounds showed different inhibitory activities against seven plant pathogenic fungi. Compounds 1, 12, 17, 20, 22, 24 intermediate A more than 90% inhibition rates S. s at 50 mg/L. Interestingly, compound 22 the great effect with EC50 values 4.65 4.24 mg/L, better lead (EC50 =...

10.1002/cbdv.202401955 article EN Chemistry & Biodiversity 2024-09-04

Abstract In this study, light-emitting diode (LED) was used as light source to cultivate pakchoi in hydroponics. The effects of red and far ratio (R: FR) 0.7, 1.0 4.2(CK) on the growth photosynthetic characteristics under different nitrate stress concentrations were studied. results showed that indexes, gas exchange parameters (except intercellular CO 2 concentration) decreased significantly excess stress. And more inhibited high concentration. Under low R: FR ratio, indexes net rate...

10.1088/1755-1315/621/1/012105 article EN IOP Conference Series Earth and Environmental Science 2021-01-01

Abstract BACKGROUND Cationic antimicrobial peptides (AMPs) possess broad‐spectrum biological activities with less inclination to inducing antibiotic resistance. Herein a battery of amphiphilic amidines were designed by mimicking the characteristics AMPs. The antifungal and effects hyphal morphology membrane permeability investigated. RESULTS results indicated inhibitory rates ten compounds over 80% Botrytis cinerea 90% Valsa mali Miyabe et Yamada at 50 mg L −1 . half maximal effective...

10.1002/ps.8253 article EN Pest Management Science 2024-06-14

As part of continuous work to explore novel and efficient fungicides originating from natural products, a series cyclobutyl oxime ester derivatives containing an α,β-unsaturated carbonyl moiety were designed synthesized. In line with the primary evaluation inhibitory effect on common pathogenic fungi causing crop failure, systematic study antifungal activity target compounds against

10.1021/acs.jafc.4c05066 article EN Journal of Agricultural and Food Chemistry 2024-09-25
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