A5037826798- Medical and Biological Sciences
- Dental Implant Techniques and Outcomes
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Bone Tissue Engineering Materials
- RNA modifications and cancer
- Intensive Care Unit Cognitive Disorders
- Ferroptosis and cancer prognosis
- Esophageal Cancer Research and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Biomarkers in Disease Mechanisms
- Neuroscience of respiration and sleep
- Heavy Metal Exposure and Toxicity
- Electrolyte and hormonal disorders
- Digital Imaging in Medicine
- Oral Health Pathology and Treatment
- Therapeutic Uses of Natural Elements
- Cleft Lip and Palate Research
- Cancer Mechanisms and Therapy
- Lymphatic System and Diseases
- Gastrointestinal motility and disorders
- Pancreatic and Hepatic Oncology Research
- Cancer-related molecular mechanisms research
- Trace Elements in Health
- Dysphagia Assessment and Management
Changzhou No.2 People's Hospital
2025
Nanjing Medical University
2025
Beijing Chao-Yang Hospital
2017-2024
Capital Medical University
2009-2024
China Rehabilitation Research Center
2022-2024
Weatherford College
2024
National Clinical Research Center for Digestive Diseases
2017
Beijing Friendship Hospital
2017
Kidney disease secondary to mercury poisoning has not been well documented and is often misdiagnosed mistreated.We performed a retrospective analysis of patients diagnosed with having over 6-year period between July 2013 June 2019. Demographics, clinical measures, renal pathologic examinations, treatments, outcomes were compared kidney those without disease.Of the 172 poisoning, 46 (26.74%) had damage. Among patients, 41 (89.13%) presented nephrotic syndrome, 5 (10.87%) showed proteinuria...
Aim Study results on blood glucose and the risk of delirium in patients receiving cardiac surgery are inconsistent, there is also a gap how to manage after coronary artery bypass grafting (CABG). This study focused with diabetes mellitus (DM) undergoing CABG explored associations different glucose-related indexes change trajectory postoperative (POD), aim providing some information for management this population. Methods Data DM were extracted from Medical Information Mart Intensive Care...
Objective: To investigate the efficacy and adverse reactions of caffeine citrate in treatment primary apnea prematurity(AOP) its effect on long-term development preterm infants. Methods: This was a retrospective study. One hundred forty six infants with AOP treated Neonatal Department Second People’s Hospital Changzhou Affiliated to Nanjing Medical University between December 2019 2023 were divided into low-dose group (5mg/kg) high-dose (10 mg/kg) according maintenance doses caffeine, 73...
Gastric cancer typically originates from the abnormal proliferation of normal cells within gastric mucosa, eventually forming tumors. The roles sperm-associated antigen 5 (SPAG5) and spindle-like microcephaly (ASPM) associated genes in are not yet clear. datasets GSE51575 GSE36076 profiles were downloaded GPL13607 GPL570-generated gene expression omnibus database. analysis included filtering for differentially expressed genes, weighted co-expression network analysis, functional enrichment...
Colorectal cancer (CRC) is one of the most common malignancies worldwide. The 5‑year survival rate patients diagnosed with early stages disease markedly higher than that in advanced stages. Therefore, identifying novel biomarkers and drug targets for CRC critical clinical practice. Zinc finger protein 169 (ZNF169) a crucial transcription factor, its role remains to be explored. present study aimed investigate relevance, function underlying mechanisms ZNF169 growth proliferation. Cancer...
Septic shock is the development of sepsis to refractory circulatory collapse and metabolic derangements, characterized by persistent hypotension increased lactate levels. Anisodamine hydrobromide (Ani HBr) a Chinese medicine used improve blood flow in disorders. The purpose this study was determine therapeutic efficacy Ani HBr treatment patients with septic shock.This prospective, multicenter, randomized controlled trial focusing on 16 hospitals China. Patients were randomly assigned 1:1...
To determine whether oxidative stress and inflammation are associated with constipation by examining the expression of main producers reactive oxygen species, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, pro-inflammatory cytokines in colon patients chronic functional constipation. The colonic biopsies were collected from 32 30 healthy subjects who underwent colonoscopy. Colonic mucosal histology was observed. Interleukin (IL)-1β, IL-6, IL-8 messenger RNA (mRNA), 4 members...
The esophageal squamous cell carcinoma (ESCC) is usually develped from low-grade intraepithelial neoplasia (LGIEN) and high-grade (HGIEN) to infiltrative carcinoma. Till now, it remains hard screen for infiltration at earlier stages, especially the differentiation between HGEIN early purpose of this study determine a role podoplanin in differentiating Totally 133 patients pathologically diagnosed with ESCC and/or precancerous lesions were enrolled.The EnVision two-step IHC staining technique...
The alteration of metabolism is essential for the initiation and progression numerous types cancer, including colorectal cancer (CRC). Metabolomics has been used to study CRC. At present, reprogramming in CRC remains be fully elucidated. In present study, comprehensive untargeted metabolomics analysis was performed on paired tissues adjacent normal from patients with (n=35) using ultra‑high‑performance liquid chromatography‑mass spectrometry. Subsequently, bioinformatic differentially...
Colorectal cancer (CRC) is the third most frequent worldwide. The AHCYL1 gene required for CNV and has a close association with tumor immune microenvironment. However, predictive value of in patients CRC remains unknown.AHCYL1 prognostic potential was comprehensively analyzed. Next, using LASSO Cox regression, we fully examined integrated AHCYL1-related genes from TCGA database. Meanwhile, database used to study connection between microenvironment mutation burden (TMB) CRC. influence growth...
Objectives: To evaluate the diagnostic value of CT for lymph node metastasis thoracic esophageal carcinoma with a diameter more than 1 cm, and to find optimal index by comparing relevant indexes. Methods: Totally 80 patients pathologically proved cancer preoperative examination revealed greater cm admitted at Department Thoracic Surgery, First Affiliated Hospital University Science Technology China from January 2016 2018 were enrolled in this study. There 70 males 10 females, aging (60±14)...
<h3>Importance</h3> Postoperative delirium is a frequent disorder for patients undergoing surgery and associated with poor outcomes. Delirium may occur in the immediate period after anesthesia administration surgery. Tropisetron, which frequently administrated postoperative nausea vomiting, also partial agonist of α7 nicotinic acetylcholine receptors neuroprotective effects. Tropisetron be potential pharmacological treatment to decrease noncardiac <h3>Objective</h3> To perform randomized...
Acute pancreatitis (AP) is one of the life-threatening diseases digestive system. MicroRNA has been asserted to be a regulator AP. This paper explored miR-374a-5p expression in AP patients and investigated efficacy AR42J cells. In this study, 60 healthy people, 58 MAP SAP were included, serum levels subjects detected by RT-qPCR technology. The cell model was structured stimulating cells with cerulein. Next, viability apoptosis CCK-8 assay flow cytometry. ELISA used measure concentration...
Objective To summarize the effect of mechanical insufflation exsufflation (MIE) used in 202 patients ICU Beijing Chao-Yang Hospital. Methods The research was a retrospective study, and collected patients'social demographic clinical information (vital signs、respiratory parameters、times sputum suction/cough so on). Results The diagnosis included primary lung disease、neuromuscular diseases other critical disease.The vital signs respiratory parameters before after MIE had no...