A5102801744- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Cerebral Palsy and Movement Disorders
- Cervical and Thoracic Myelopathy
- Stroke Rehabilitation and Recovery
- Musculoskeletal pain and rehabilitation
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Lower Extremity Biomechanics and Pathologies
- Peripheral Nerve Disorders
- Foot and Ankle Surgery
- Periodontal Regeneration and Treatments
- Muscle activation and electromyography studies
- Heart Rate Variability and Autonomic Control
- Balance, Gait, and Falls Prevention
- Hip and Femur Fractures
- Sports injuries and prevention
- Spinal Hematomas and Complications
- Cardiovascular and exercise physiology
- Autoimmune and Inflammatory Disorders Research
- Spinal Cord Injury Research
- Medical Imaging and Analysis
- Osteoarthritis Treatment and Mechanisms
- Cardiac Health and Mental Health
- Viral Infections and Immunology Research
Kyoto Prefectural University of Medicine
2016-2025
University Hospital Kyoto Prefectural University of Medicine
2017-2025
University of Tsukuba
2024
The University of Tokyo
2024
Kyoto Prefectural Institute of Public Health and Environment
2024
University of Tokyo Hospital
2024
Tokushima Hospital
2024
Kumamoto University
2023
John Wiley & Sons (United States)
2021
Japan Pediatric Society
2020
This study evaluated the regenerative effects of platelet-rich plasma (PRP) for degenerated intervertebral disc (IVD) in vivo. After induction IVD degeneration rabbits, we prepared PRP by centrifuging blood obtained from these rabbits. These were injected into nucleus pulposus (NP) IVDs after impregnation gelatin hydrogel microspheres that can immobilize growth factors physiochemically and release them a sustained manner with degradation microspheres. As controls, impregnated...
Lumbar disc degeneration (LDD) is associated with both genetic and environmental factors affects many people worldwide. A hallmark of LDD loss proteoglycan water content in the nucleus pulposus intervertebral discs. While some determinants have been reported, etiology largely unknown. Here we report findings from linkage association studies on a total 32,642 subjects consisting 4,043 cases 28,599 control subjects. We identified carbohydrate sulfotransferase 3 (CHST3), an enzyme that...
In Brief Study Design. Retrospective multi-institutional study Objective. To describe the surgical outcomes in patients with ossification of posterior longitudinal ligament thoracic spine (T-OPLL) and to clarify factors related outcomes. Summary Background Data. Detailed analyses T-OPLL have been difficult because rarity this disease. Methods. The subjects were 154 who surgically treated at 34 institutions between 1998 2002. procedures laminectomy 36, laminoplasty 51, anterior decompression...
We have previously shown that administration of platelet-rich plasma–impregnated gelatin hydrogel microspheres (PRP-GHMs) into a degenerated intervertebral disc (IVD) markedly suppresses progression IVD degeneration. In the current study, we characterized in vivo effects PRP-GHM treatment model rabbit. On magnetic resonance images, height was significantly greater after with PRP-GHMs compared phosphate-buffered saline–impregnated GHMs, PRP without and needle puncture only. Water content also...
The purpose of this study was to clarify the relationship between initial radiographs osteoporotic vertebral compression fractures (VCFs) and clinical results.Of 135 VCFs in elderly, 73 consecutive patients (84 vertebrae) were reviewed retrospectively. All treated without rigid immobilization. subjects consisted 15 men 58 women. mean age 75.0 years with a range from 61 91 years. early radiographic features classified into five types based on lateral radiographs. Radiographic results during...
Evaluation was done of 65 patients with cervical myelopathy treated by bilateral open laminoplasty using artificial laminas, between 1984 and 1988, who had been followed for more than 2 years. The mean recovery rate on the Japanese Orthopaedic Association scoring system 65% in all cases, 72% cases no other complications. laminas appeared well adapted to computed tomography dynamic radiographic examinations, there were reduction enlarged canal. Postoperative restriction range motion spine...
Posterior cervical spinal cord shifting after selective single laminectomy associated with partial laminotomies was compared that bilateral open-door laminoplasty between the C3 and C7 levels in relation to clinical results of each procedure.To investigate significance posterior extensive laminoplasty.Current techniques used for multisegmental spondylotic myelopathy (CSM) are consecutively performed C6 or expectation will shift backward keep it clear anterior compression. However, remains...
In Brief Study Design. Outcomes of muscle-preserving interlaminar decompression (MILD) for the lumbar spine are reported. Objective. To verify clinical findings MILD. Summary Background Data. A preliminary short-term follow-up study MILD demonstrated satisfactory neural recovery and reduced invasiveness. Methods. The initial 105 consecutive patients with spinal canal stenosis were included in this study. total 210 intervertebral levels decompressed. There 48 women 57 men, mean patient age...
Lumbar disc herniation (LDH) is one of the most common musculo-skeletal diseases. Recent studies have indicated that LDH has strong genetic determinants, and several susceptibility genes been reported to associate with LDH; however, its etiology pathogenesis still remain unclear. KIAA1217 (alias SKT, human homolog murine Skt [Sickle tail]) a good candidate for an gene because SKT specifically expressed in nucleus pulposa intervertebral discs (IVDs) humans mice, Skt(Gt) which are established...
Disorders of the cervical spine are often observed in patients with rheumatoid arthritis (RA). However, best head position for RA atlantoaxial subluxation perioperative period is unknown. This study investigated during general anesthesia and proven subluxation.During subluxation, authors used fluoroscopy to obtain a lateral view upper four different positions: mask position, intubation flat pillow protrusion position. Copies still fluoroscopic images were determine anterior atlantodental...
We developed a novel method for bone fusion by combining platelet-rich plasma (PRP) and gelatin β-tricalcium phosphate (β-TCP) sponge. The PRP is an autologous concentration of platelets that includes several growth factors. β-TCP sponge comprises β-TCP, thus enabling the sustained release factors osteoconduction. To evaluate this method, we generated posterolateral model lumbar vertebrae in rats divided it into five groups implanting following materials between transverse processes...
There are reports that fusion is the standard treatment of choice for cases lumbar degenerative spondylolisthesis (LDS) associated with spinal canal stenosis a large degree slippage. The reasons why, however, have not been clarified. On other hand, it known progress slippage decreases and restabilization occurs over natural course LDS. Therefore, if minimally invasive decompression could be performed, there would little possibility influencing LDS, so necessary to include preoperative...
Although epidemiological studies on epiphyseal injury have been reported, such not made systematically in Japan. In this study, we examined the incidence of paediatric patients treated at five general hospitals and three private clinics. We with limb injuries between January 1992 December 1997, reviewed them least 18 months after original injuries. The radiograms completed case records were classified according to age sex injured children, site fracture, type treatment, its complications....
In Brief Study Design. A case-series study. Objectives. To measure the 3-dimensional (3D) morphology and kinematics of craniovertebral junction (CVJ) using a 3D computed tomography (CT) model; to reveal abnormal patterns relationships between pathology kinematics. Summary Background Data. Evaluations radiography, 2-dimensional (2D) CT magnetic resonance imaging have limitations because complex structure CVJ. Methods. Twenty-four rheumatoid arthritis patients (21 females, 3 males) with...