A5101899166- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Treatment and Research
- Urological Disorders and Treatments
- Urinary and Genital Oncology Studies
- Urologic and reproductive health conditions
- Urinary Bladder and Prostate Research
- Renal cell carcinoma treatment
- Pediatric Urology and Nephrology Studies
- Ureteral procedures and complications
- Cardiac, Anesthesia and Surgical Outcomes
- Pelvic floor disorders treatments
- Colorectal Cancer Surgical Treatments
- Hormonal and reproductive studies
- Renal and related cancers
- Asthma and respiratory diseases
- Genital Health and Disease
- Health Systems, Economic Evaluations, Quality of Life
- Surgical Simulation and Training
- Renal and Vascular Pathologies
- Respiratory and Cough-Related Research
- Kidney Stones and Urolithiasis Treatments
- Minimally Invasive Surgical Techniques
- Advanced Radiotherapy Techniques
- Cancer, Lipids, and Metabolism
King's College London
2023-2024
Vanderbilt University
2008-2024
Newcastle University
2020-2024
Brookwood Baptist Health
2024
Vanderbilt University Medical Center
2014-2023
Wilmington University
1991-2021
Nashville Oncology Associates
2010-2019
Mayo Clinic Hospital
2017
Meharry Medical College
2016
University of Oklahoma
2016
Benign prostatic hyperplasia is commonly treated with alpha-adrenergic-receptor antagonists (alpha-blockers) or 5alpha-reductase inhibitors. The long-term effect of these drugs, singly combined, on the risk clinical progression unknown.We conducted a long-term, double-blind trial (mean follow-up, 4.5 years) involving 3047 men to compare effects placebo, doxazosin, finasteride, and combination therapy measures benign hyperplasia.The overall progression--defined as an increase above base line...
In carcinoma of the bladder, both intravesical chemotherapy and immunotherapy can induce tumor regression reduce rate recurrence, but relative merits these two therapies are unclear. We conducted a multi-institutional study to address this question.
Radical cystectomy remains associated with significant morbidity. Most series report outcomes relatively short-term followup that may underestimate the true magnitude of procedure and many length hospital stay but ignore readmission rates. We analyzed predictors early (30 days or less), late (31 to 90 days) cumulative 90-day readmissions, as well morbidity mortality rates.We reviewed our prospectively collected database 753 patients who underwent radical for urothelial cancer between January...
Abstract Cribriform prostate cancer, found in both invasive cribriform carcinoma (ICC) and intraductal (IDC), is an aggressive histological subtype that associated with progression to lethal disease. To delineate the molecular cellular underpinnings of ICC/IDC aggressiveness, this study examines paired benign surgical samples by single-cell RNA-sequencing, TCR sequencing, histology. cancer cells express genes metastasis targets potential for therapeutic intervention. Pathway analyses...
We examined our recent series of patients who underwent radical cystectomy to determine and analyze the early perioperative morbidity procedure in a contemporary treated with guidance clinical pathway.We reviewed records 304 consecutive from December 1995 July 2000. specifically evaluated complications that developed within 30 days procedure. Potential variables predictive were analyzed, including patient age, gender, race, American Society Anesthesiologists score, type urinary diversion,...
Surgical technique, patient characteristics and method of pathological review may influence surgical margin status. We evaluated the incidence location positive margins in 200 sequential robotic assisted laparoscopic radical prostatectomy open retropubic cases.From July 2002 until December 2006 a total 1,747 patients underwent at our institution (robotic 1,238, 509). From these we selected last consecutive prostatectomies performed before August 2006. Preoperative clinical including age,...
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jan 2003Randomized Prospective Evaluation Extended Versus Limited Lymph Node Dissection in Patients With Clinically Localized Prostate Cancer TRAVIS CLARK, DIPEN J. PAREKH, MICHAEL S. COOKSON, SAM CHANG, ERNEST R. SMITH, NANCY WELLS, and JOSEPH A. SMITH CLARKTRAVIS CLARK , PAREKHDIPEN PAREKH COOKSONMICHAEL COOKSON CHANGSAM CHANG SMITHERNEST WELLSNANCY WELLS SMITHJOSEPH View All Author...
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Aug 2001CLINICAL UNDER STAGING OF HIGH RISK NONMUSCLE INVASIVE UROTHELIAL CARCINOMA TREATED WITH RADICAL CYSTECTOMY SAJAL C. DUTTA, JOSEPH A. SMITH, SCOTT B. SHAPPELL, CHRISTOPHER S. COFFEY, SAM CHANG, and MICHAEL COOKSON DUTTASAJAL DUTTA , SMITHJOSEPH SMITH SHAPPELLSCOTT SHAPPELL COFFEYCHRISTOPHER COFFEY CHANGSAM CHANG COOKSONMICHAEL View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)65969-1AboutFull TextPDF...
Poor preoperative nutritional status is a risk factor for adverse outcomes after major surgery. We evaluated the effect of deficiency on perioperative mortality and overall survival in patients undergoing radical cystectomy bladder cancer.A total 538 underwent urothelial carcinoma between January 2000 June 2008, had parameters documented. Patients with albumin less than 3.5 gm/dl, body mass index 18.5 kg/m(2) or weight loss greater 5% were considered to have deficiency. Primary 90-day...
We analyzed data from the placebo arm of MTOPS trial to determine clinical predictors BPH progression.A total 3,047 patients with LUTS were randomized either placebo, doxazosin (4 8 mg), finasteride (5 or a combination and finasteride. Average length followup was 4.5 years. The primary outcome time overall progression BPH, defined as confirmed 4-point greater increase in AUA SS, acute urinary retention, incontinence, renal insufficiency, recurrent tract infection. event 737 men who...
The prognosis for patients with bladder cancer metastatic to regional lymph nodes is dismal and only minimally altered by current treatment modalities. 5-year survival rate after radical cystectomy 134 positive was 7 per cent 82 of the died cancer. Stratification into groups varying extent nodal disease showed a correlation between level involvement interval recurrence. While 38 distant alone 25 had pelvic recurrence, indicating possible therapeutic effect systmatic bilateral lymphadenectomy...
The feasibility of laparoscopic or robotic assisted radical cystectomy has been demonstrated in several small series, but the specific advantages are uncertain and require comparisons to more recent results that incorporate refinements open technique perioperative management. We reviewed our contemporary series evaluate outcome measures which could be affected by surgical approach for purpose establishing benchmarks future comparisons.The medical records 553 consecutive patients undergoing...
Health related quality of life after urinary diversion has been increasingly recognized as an important outcome measure. However, few studies have directly compared patients with ileal conduit those a continent orthotopic neobladder and even fewer used validated instruments. Therefore, we health in who underwent versus creation using questionnaires.We mailed 2 questionnaires that are measures life, namely the RAND 36-Item Survey (SF-36) Functional Assessment Cancer Therapy-General (FACT-G),...
Minimally invasive surgery has been shown to decrease postoperative morbidity and length of stay for a number surgical procedures. Furthermore, after open radical prostatectomy decreased dramatically during the last decade. We examined differences in between prospectively evaluated cohort patients who underwent retropubic robot assisted laparoscopic prostatectomy.Between January 2003 March 2006, 1,003 prostatectomies were performed at our hospital. Data collected prospective fashion...
No AccessJournal of UrologyAdult Urology: Oncology: Prostate/Testis/Penis/Urethra1 Sep 2005ROBOTIC ASSISTED LAPAROSCOPIC RADICAL PROSTATECTOMY VERSUS RETROPUBIC PROSTATECTOMY: A PROSPECTIVE ASSESSMENT OF POSTOPERATIVE PAIN TODD M. WEBSTER, S. DUKE HERRELL, SAM CHANG, MICHAEL COOKSON, ROXELYN G. BAUMGARTNER, LAURA W. ANDERSON, and JOSEPH A. SMITH WEBSTERTODD WEBSTER , HERRELLS. HERRELL CHANGSAM CHANG COOKSONMICHAEL COOKSON BAUMGARTNERROXELYN BAUMGARTNER ANDERSONLAURA ANDERSON SMITHJOSEPH View...
No AccessJournal of Urology1 Jan 1989Palliation Painful Bone Metastases from Prostate Cancer Using Sodium Etidronate: Results a Randomized, Prospective, Double-Blind, Placebo-Controlled Study Joseph A. Smith SmithJoseph More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)40597-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail etidronate is diphosphonate compound that inhibits bone...
Prostatic carcinoma (Pca) at cystoprostatectomy is usually an incidental finding with the majority thought to be clinically insignificant. Most studies have not specifically addressed location of Pca or incidence and in situ invasive urothelial (Uca) prostates specimens. The frequency involvement apex these processes has clinical implications. Specifically urinary continence following orthotopic diversion may enhanced by prostate apical sparing. In this study pathological features Uca, were...
No AccessJournal of UrologyAdult Urology1 Mar 2010Robotic Assisted Laparoscopic Prostatectomy Versus Radical Retropubic for Clinically Localized Prostate Cancer: Comparison Short-Term Biochemical Recurrence-Free Survival Daniel A. Barocas, Shady Salem, Yakup Kordan, S. Duke Herrell, Sam Chang, Peter E. Clark, Rodney Davis, Roxelyn Baumgartner, Sharon Phillips, Michael Cookson, and Joseph Smith BarocasDaniel Barocas , SalemShady Salem KordanYakup Kordan HerrellS. Herrell ChangSam Chang...