A5018410336- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Gestational Diabetes Research and Management
- Dengue and Mosquito Control Research
- Mosquito-borne diseases and control
- Malaria Research and Control
- Pancreatic function and diabetes
- Diabetes Management and Research
- COVID-19 diagnosis using AI
- Metabolism, Diabetes, and Cancer
- Health Promotion and Cardiovascular Prevention
- Vitamin D Research Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Health and Risk Factors
- Food Allergy and Anaphylaxis Research
- Pain Mechanisms and Treatments
- COVID-19 and healthcare impacts
- Wireless Body Area Networks
- Healthcare Systems and Reforms
- Vaccine Coverage and Hesitancy
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Electronic Health Records Systems
- Clinical Nutrition and Gastroenterology
- Parkinson's Disease Mechanisms and Treatments
- Drug-Induced Ocular Toxicity
Hospital Seberang Jaya
2015-2022
Ministry of Health
2018-2021
Sultan Abdul Halim Hospital
2015-2020
Center for Clinical Research (United States)
2020
Waikato Hospital
2010
Ollscoil na Gaillimhe – University of Galway
2010
Galway Clinic
2010
<h3>Importance</h3> Ivermectin, an inexpensive and widely available antiparasitic drug, is prescribed to treat COVID-19. Evidence-based data recommend either for or against the use of ivermectin are needed. <h3>Objective</h3> To determine efficacy in preventing progression severe disease among high-risk patients with <h3>Design, Setting, Participants</h3> The Ivermectin Treatment Efficacy COVID-19 High-Risk Patients (I-TECH) study was open-label randomized clinical trial conducted at 20...
COVID-19 emerged as a major public health outbreak in late 2019. Malaysia reported its first imported case on 25th January 2020, and adopted policy of extensive contact tracing hospitalising all cases. We describe the clinical characteristics cases nationwide determine risk factors associated with disease severity.Clinical records RT-PCR confirmed aged ≥12 years admitted to 18 designated hospitals between 1st February 30th May 2020 complete outcomes were retrieved. Epidemiological history,...
Management of painful diabetic peripheral neuropathy remains challenging. Most therapies provide symptomatic relief with varying degrees efficacy. Tocotrienols have modulatory effects on the pathway and may reduce neuropathic symptoms their antioxidative anti-inflammatory activities.To evaluate efficacy oral mixed tocotrienols for patients neuropathy.The Vitamin E in Neuroprotection Study (VENUS) was a parallel, double-blind, placebo-controlled trial that recruited participants from January...
Each year an estimated 390 million dengue infections occur worldwide. In Malaysia, is a growing public health concern but estimate of its disease burden remains uncertain. We compared the urban-rural difference seroprevalence and determined age-specific in Malaysia. undertook analysis on 11,821 subjects from six surveys conducted Malaysia between 2001 2013, which composed five urban two rural series. Prevalence increased with age both locations exceeded 90 % among those aged 70 years or...
Abstract Background The role of favipiravir in preventing disease progression coronavirus 2019 (COVID-19) remains uncertain. We aimed to determine its effect from nonhypoxia hypoxia among high-risk COVID-19 patients. Methods This was an open-label, randomized clinical trial conducted at 14 public hospitals across Malaysia (February–July 2021) 500 symptomatic, RT-PCR–confirmed patients, aged ≥50 years with ≥1 comorbidity, and hospitalized within first 7 days illness. Patients were 1:1 plus...
Abstract Background Electronic clinical decision support (CDS) is increasingly establishing its role in evidence-based practice. Considerable evidence supports enhancement of efficiency e-Prescribing, but some controversy remains. This study evaluated the practicality and identified perceived benefits of, barriers to, future adoption West Ireland. Methods cross sectional was carried out by means a 27-part questionnaire sent to 262 registered general practitioners Counties Galway, Mayo...
Epidemiologic measures of the dengue burden such as prevalence and incidence are important for policy-making monitoring progress disease control. It is a common practice where epidemiologic economic research estimate based on notification data. However, basic challenge in estimating that significant proportion infected population asymptomatic. can be overcome by using mathematical models relate observed mortality to incidence. In this study, we trend hospitalization Malaysia. This study...
Youth onset type 2 diabetes mellitus (YT2DM) is a globally rising phenomenon with substantial Asians representation. The understanding of its pathophysiology derived largely from studies in the obese African-American and Caucasian populations, while on incretin effect are scarce. We examined insulin resistance, β-cell function (BC), glucagon-like peptide (GLP)-1 hormone Asian YT2DM.This case-control study recruited 25 YT2DM 15 healthy controls, matched for gender, ethnicity body mass index....
Gestational Diabetes Mellitus (GDM) and vitamin D deficiency are related to insulin resistance impaired beta cell function, with heightened risk for future development of diabetes. We evaluated the impact supplementation on markers glucose metabolism cardio metabolic in Asian women former GDM hypovitaminosis D. In this double blind, randomized controlled trial, 26 participants were receive either daily 4000 IU D3 or placebo capsules. 75g Oral Glucose Tolerance Test (OGTT) biochemistry...
The escalated burden of diabetes on the population’s health has catalyzed rigorous scientific research to produce appropriate evidence for treatment and control. Malaysia suffers from leading epidemic within Western Pacific region. It is crucial map landscape country identify trends in productivity determine whether efforts are directed toward needs-gaps priority synthesis that could be used drafting policies guidelines. This systematic scientometrics study was conducted output (trends...
It remains widely perceived that early-onset Type 2 Diabetes (T2D) in children and adolescents is rare clinically distinct from 1 (T1D). We studied the challenges of classifying subtypes diabetes using clinical features biomarkers, management these patients. reviewed retrospectively record patients < 25 years old who attended clinic Penang General Hospital, Malaysia between 1st December 2012 30th June 2015. examined their features, C-peptide pancreatic autoantibodies. Comparisons were made...
Introduction: The importance of insulin clearance (CLins) on dynamics and the role exerted in controlling glucose type 2 subjects has recently been appreciated. Moreover, evidence mice showed that CLins is reduced by incretin hormones at physiological levels. Aim: To evaluate 29 young (19±1 years) multi-ethnic Asian (T2D) contribution to if an association exists with GLP-1. Methods: T2D (15F/14M; BMI=30.2±0.9 kg/m2; HbA1c=8.8±0.4% [73±4.4 mmol/mol]; mean duration disease 2.5 had fasting...