Abhinav Gupta

ORCID: 0000-0003-0127-1462
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About
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Research Areas
  • Cholesterol and Lipid Metabolism
  • Genetic Syndromes and Imprinting
  • Thyroid Disorders and Treatments
  • Glioma Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Congenital heart defects research
  • Growth Hormone and Insulin-like Growth Factors
  • Pancreatic and Hepatic Oncology Research
  • Anorectal Disease Treatments and Outcomes
  • Prenatal Screening and Diagnostics
  • HIV Research and Treatment
  • Surgical Simulation and Training
  • Adipokines, Inflammation, and Metabolic Diseases
  • Blood groups and transfusion
  • Infectious Encephalopathies and Encephalitis
  • Vaccine Coverage and Hesitancy
  • Microscopic Colitis
  • Peripheral Neuropathies and Disorders
  • Drug Transport and Resistance Mechanisms
  • Autoimmune and Inflammatory Disorders
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Genomic variations and chromosomal abnormalities
  • Viral Infections and Outbreaks Research
  • Pediatric Pain Management Techniques
  • Dermatological and COVID-19 studies

University of Southern California
2025

Keck Hospital of USC
2025

Acharya Shri Chander College of Medical Sciences and Hospital
2025

Johns Hopkins University
2024

Public Works Department Buildings and Roads
2023

Government Medical College
2021

Children's Hospital Colorado
2019

University of Colorado Denver
2019

Momenta Pharmaceuticals (United States)
2019

Lala Lajpat Rai Memorial Medical College
2015-2017

<title>Abstract</title> Background: Anastomotic leak is a serious complication of bowel anastomosis, with multifactorial etiology. Thorough intraoperative evaluation the anastomosis using white light endoscopy and tests critical. Indocyanine green fluorescence angiography (ICG-FA) has emerged as tool to assess perfusion but limitations, including patient allergies procedural complexity. The FUJIFILM Eluxeo Vision system uses Oxygen Saturation Index (OSI) measure tissue oxygenation saturation...

10.21203/rs.3.rs-6009922/v1 preprint EN cc-by Research Square (Research Square) 2025-02-19

ABSTRACT Background: People working in health care are particularly vulnerable to catching influenza infection as they always exposed probable cases hospital settings. Influenza is a communicable disease that transmits from patients healthcare workers (HCWs) and vice versa. Contrary most of the recommendations, vaccination coverage among HCWs low. Aims: This study intends assess knowledge, attitude practices towards group HCWs. Materials Methods: In this cross-sectional conducted, 128...

10.4103/cmrp.cmrp_100_24 article EN cc-by-nc-sa Current Medicine Research and Practice 2025-01-01

Gammaretroviral and lentiviral vectors have been used successfully in several clinical gene therapy trials, although powerful enhancer elements caused insertional mutagenesis clonal dysregulation. Self-inactivating with internal heterologous regulatory developed as potentially safer more effective alternatives. Lentiviral containing a ubiquitous chromatin opening element from the human HNRPA2B1-CBX3 locus (A2UCOE), which allows position-independent, long-term transgene expression, are...

10.1128/jvi.00485-12 article EN Journal of Virology 2012-06-14

Background: Juvenile hypothyroidism is a very common problem in developing parts of world, and produces various skeletal manifestations. One them short stature it the most reason for referral to endocrinologist. Aim Objectives: To study prevalence juvenile hypothyroidism, radiological manifestations impact treatment on growth velocity Materials Methods: Out total nine hundred hypothyroid patients, eighty seven patients found be were enrolled those 6-18 years age with newly diagnosed or...

10.4103/2348-3334.158704 article EN cc-by-nc-sa CHRISMED Journal of Health and Research 2015-01-01

Human Immunodeficiency Virus (HIV) infection is a global pandemic. According to the data released by UNAIDS in 2007, India had 2.5 million people living with HIV infection.[1] Next sub-Saharan Africa, it has second largest burden of HIV-related illness. Though main targets are cells immune system, nervous system often damaged during course infection, not only disease processes that secondary dysfunction but also more fundamental effects retrovirus.

10.4103/1947-2714.103329 article EN North American Journal of Medical Sciences 2012-01-01

Virtual reality (VR), a computer-generated simulation of 3-dimensional environment, is relatively new method providing distraction before and during procedures. We describe the use VR multiuser application, Oculus Rooms, to calm an anxious 10-year-old boy transportation operating room induction anesthesia. The could lessen perioperative anxiety children by maintaining virtual child-parent connection while avoiding potential drawbacks having parents actually in success this novel technique...

10.1213/xaa.0000000000001114 article EN A&A Practice 2019-09-10

Van Wyk-Grumbach syndrome (VWGS) is a rare presentation of juvenile hypothyroidism which manifests in females as chronic autoimmune hypothyroidism, isosexual pseudoprecocious puberty, and multicystic ovaries. It uniquely presents with short stature delayed bone age unlike other causes precocious puberty. Kocher-Debré-Sémélaigne (KDSS) manifesting calf muscle pseudohypertrophy, contraction relaxation reflexes, percussion myxedema.To diagnose the association VWGS KDSS to conduct follow-up...

10.1159/000448993 article EN European Thyroid Journal 2016-10-03

Cerebrotendinous xanthomatosis is a very rare autosomal recessive lipid storage disorder affecting bile acid biosynthesis. It manifested by subtle neurological and non-neurological symptoms due to abnormal tissue deposition. Diagnosis usually delayed but early diagnosis replacement therapy can prevent devastating sequelae. We present case of 25-year-old Asian Indian woman who presented with gait difficulty, fusiform swellings bilateral tendo-Achilles infrapatellar tendons, along history...

10.1186/s13256-016-0882-y article EN cc-by Journal of Medical Case Reports 2016-04-19

Dengue fever is an important public health problem in India and has various serious manifestations, which if not identified treated at appropriate time can lead to dire consequences. Quadriparesis during the course of dengue infection quite unusual rarely reported. The authors hereby report a case acute motor quadriparesis due Guillain–Barre syndrome infection, who showed gradual response conservative treatment.

10.1136/bcr.02.2011.3839 article EN BMJ Case Reports 2011-06-29

Blepharophimosis ptosis epicanthus inversus (BPES) is a relatively rare congenital disorder, which usually presents with classical eye manifestations.In some cases, it associated premature ovarian failure (POF).BPES of two types, type I and II.Type POF along eyelid malformations, while Type 2 has only malformations.Here, we report family BPES, in whom sisters presented secondary amenorrhea.On examination, they have blepharophimosis, ptosis, telecanthus.Investigations revealed...

10.15605/jafes.032.01.13 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2017-05-31

Skeletal muscles express and elaborate a number of cytokines other substances for modulating various metabolic processes which function locally also target distant organs are known as myokines. Irisin is one the most recently discovered myokines found to modulate effect exercise on adipocytes through browning white adipose tissue. Besides this, irisin considered be future targets therapies disorders.

10.4103/2347-9906.184171 article EN Journal of Obesity and Metabolic Research 2016-01-01

Abstract CD38 targeting antibodies are at different phases of clinical development, with daratumumab already approved as monotherapy and in combination standards care multiple myeloma (MM). Anti-CD38 monoclonal (mAbs) induce tumor cell depletion part by Fc-dependent effector mechanisms such antibody dependent cellular cytotoxicity (ADCC), phagocytosis (ADCP), complement (CDC). However, not all MM patients achieve minimal residual disease (MRD)-negativity similar response. In addition, some...

10.1158/1538-7445.am2019-561 article EN Cancer Research 2019-07-01

Fibrous dysplasia (FD) is sometimes accompanied by extraskeletal manifestations that can include any combination of café-au-lait macules, hyperfunctioning endocrinopathies, such as gonadotropin-independent precocious puberty, hyperthyroidism, growth hormone excess, FGF23-mediated renal phosphate wasting, and/or Cushing's syndrome, well other less common features.The these findings, with or without FD, known McCune-Albright syndrome (MAS).The broad spectrum involved tissues and the...

10.15605/jafes.030.01.05 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2015-05-11

Lymphocytic hypophysitis is a neuroendocrine disorder characterized by autoimmune infiammation of the pituitary gland with various degrees dysfunction. Coexistence other conditions reported in vast majority cases. The clinical presentation varies depending on segment that more severely affected. Early destruction ACTH producing cells characteristic feature lymphocytic adenohypophysitis. Other anterior hormones can also be affected, but posterior involvement absent or minimum....

10.4103/2394-7438.166302 article EN cc-by-nc-sa MAMC Journal of Medical Sciences 2015-01-01

The association of Pseudohypoparathyroidism (PHP) with Turner syndrome is very rare and only a single case has been reported so far.Both manifest short stature lack secondary sexual characteristics along other stigmata similar to each other, creating diagnostic dilemma.We describe 15-year-old Asian Indian female who presented delayed puberty overlapping phenotype PHP syndrome.The diagnosis was made easily on the basis typical history, clinical features karyotype but suspected after...

10.15605/jafes.031.02.12 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2016-08-25

10.18410/jebmh/2016/427 article EN Journal of Evidence Based Medicine and Healthcare 2016-05-12

Background and Aim: Hepatocellular Carcinoma (HCC) is the fourth most common cause of cancer-related deaths accounts for 7% all cancers worldwide. 80-90% HCCs develop against background cirrhosis. Liver biopsy, a traditional method evaluating liver fibrosis rarely used these days. Shear wave elastography has recently been employed to quantify stiffness. The current study was planned use transient as predictor long-term prognosis or occurrence HCC. Methods: After informed consent, 60 patients...

10.1016/j.jceh.2023.07.409 article EN cc-by Journal of Clinical and Experimental Hepatology 2023-01-01

Chordoid glioma of third ventricle is relatively rare and characterized by unique histomorphology varied clinical presentation. has high morbidity mortality rates despite being low grade tumor because insidious presentation difficulty in complete resection. Here, we report a new case chordoid occurring 32-year-old male, who presented with polyuria, polydipsia behavioral problems, on the water deprivation test diagnosis primary was made. MRI revealed ventricle, which resected subtotally....

10.14740/jnr.v7i4-5.457 article EN Journal of Neurology Research 2017-10-27
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