A5041594534- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- Glycosylation and Glycoproteins Research
- Glioma Diagnosis and Treatment
- Aortic aneurysm repair treatments
- Enhanced Recovery After Surgery
- Toxin Mechanisms and Immunotoxins
- Supramolecular Self-Assembly in Materials
- Immune Response and Inflammation
- Botulinum Toxin and Related Neurological Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Protein Degradation and Inhibitors
- Neonatal and Maternal Infections
- Biochemical and Structural Characterization
- Streptococcal Infections and Treatments
- Abdominal Surgery and Complications
- Cardiac Valve Diseases and Treatments
- RNA Research and Splicing
- Vascular Procedures and Complications
Saint Joseph Hospital
2024
Illinois College
2018
University of Illinois Urbana-Champaign
2018
University of California, Berkeley
2012-2014
Pacific Northwest National Laboratory
2014
Richland College
2014
A model cytotoxic T-cell epitope is linked to a synthetic lipid tail, forming peptide amphiphile that self-assembles into cylindrical micelles. The micelles are capable of inducing response in mice slows the growth tumors expressing tumor antigen.
Plant and microbial toxins are considered bioterrorism threat agents because of their extreme toxicity and/or ease availability. Additionally, some these increasingly responsible for accidental food poisonings. The current study utilized an ELISA-based protein antibody microarray the multiplexed detection ten biothreat toxins, botulinum neurotoxins (BoNT) A, B, C, D, E, F, ricin, shiga 1 2 (Stx), staphylococcus enterotoxin B (SEB), in buffer complex biological matrices. assay displayed a...
CNS Primitive Neuroectodermal tumors (CNS-PNETs) are members of the embryonal family malignant childhood brain tumors, which remain refractory to current therapeutic treatments. Current paradigm tumorigenesis implicates tumor-initiating cells (BTIC) in onset and tumor maintenance. However, despite their significance, there is currently no comprehensive characterization CNS-PNETs BTICs. Recently, we described an animal model CNS-PNET generated by orthotopic transplantation human Radial Glial...
Testicular ischemia is one of the most rarely reported complications endovascular abdominal aortic aneurysm repair (EVAR). Although pathogenesis remains unclear, thromboembolic events in setting testicular artery origin occlusion by stent graft and poor baseline collateral circulation are presumed causes. A 73-year-old man developed acute right infarction 3 days after EVAR, requiring orchiectomy. This case emphasizes importance recognizing evaluating pain EVAR counseling patients on this...
Peptide amphiphiles, synthesized by conjugating bioactive peptides to hydrophobic dialkyl tails, have been developed as a modular platform for immunotherapy, discussed M. Black, A. Trent and co-workers on page 3845. The image (by Peter Allen at UCSB) illustrates how the amphiphiles self-assemble into dynamic micellar structures in which many copies of peptide antigens are presented micelle periphery. Unlike alone, micelles, without any additional adjuvant, promote peptide-specific immune...