- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Gastrointestinal Tumor Research and Treatment
- Liver Disease Diagnosis and Treatment
- Ion Transport and Channel Regulation
- Phytase and its Applications
- Colorectal Cancer Surgical Treatments
- Innovations in Medical Education
- Cancer Mechanisms and Therapy
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Renal function and acid-base balance
- Surgical Simulation and Training
- Genetic and Kidney Cyst Diseases
- Radiology practices and education
- Polyomavirus and related diseases
- Medical Education and Admissions
- Abdominal vascular conditions and treatments
- Cardiac, Anesthesia and Surgical Outcomes
Danbury Hospital
2022-2024
University of Vermont
2022
Carolinas Medical Center
2014-2017
University of Florida
2005-2006
Florida College
2005
Abstract Background Robotic pancreaticoduodenectomy (RP) has shown some advantages over open (OP) but no data been published providing a cost comparison. Methods Retrospective analysis of all pancreaticoduodenectomies at single quaternary cancer referral center was performed. Patient demographics, comorbidities, operative characteristics, complications, and charge were recorded, then compared using standard statistical methods. Results 71 performed: 22 RP 49 OP. Patients undergoing OP had...
Chronic metabolic acidosis induces dramatic increases in net acid excretion that are predominantly due to urinary ammonia excretion. The current study examines whether this increase is associated with changes the expression of renal transporter family members, Rh B glycoprotein (Rhbg) and C (Rhcg). was induced Sprague-Dawley rats by HCl ingestion for 1 wk; control animals were pair-fed. After wk, had developed, increased significantly. Rhcg protein both outer medulla base inner medulla....
The primary mechanism by which the kidneys mediate net acid excretion is through ammonia metabolism. In current study, we examined whether chronic metabolic acidosis, increases metabolism, alters cell-specific and/or subcellular expression of transporter family member, Rhcg, in outer medullary collecting duct inner stripe (OMCDi). Chronic acidosis was induced normal SD rats HCl ingestion for 7 days; controls were pair-fed. distribution Rhcg determined using immunogold electron microscopy and...
Objective: To study and profile the digital assessment behaviors of surgical faculty residents, to build a classifier predict completion, enhancing formative feedback initiatives. Background: As competency-based paradigms are integrated into training, developing education tools for measuring competency providing rapid is crucial. Simply making assessments available inadequate results in disappointingly low user participation. optimize engagement efficacy these tools, need be studied....
Pancreaticoduodenectomy (PD) carries a significant risk. High-volume centers (HVCs) provide improved outcomes and regionalization is advocated. Rapid could, however, have detrimental effects. North Carolina has multiple HVCs, including an additional HVC added in late 2006. We investigated of PD its effects before, after, the establishment this fourth HVC. The Hospital Discharge Database was queried for all PDs performed during 2004 to 2006 2007 2009. Hospitals were categorized by volume as:...
INTRODUCTION: Pancreatic cancer (PC) screening recommendations have been based on studies performed solely at high-volume academic centers. To make PC more widely available, community-based efforts are essential. We implemented a prospective study in the community of Fairfield County, CT, and report our early safety efficacy results. METHODS: Eligible individuals were enrolled into an investigator-initiated underwent baseline 3 annual magnetic resonance imagings/magnetic...
Local ablative therapies, including microwave ablation (MWA), are common treatment modalities for in situ tumor destruction. Currently, 2.45-GHz systems gaining prominence because of the shorter application times required. The aims this study were to determine optimal power and time volume (AbV) ratios a new 1.8-mm-2.45-GHz antenna using ex vivo tissue models.The Accu2i MWA system was employed perform ablations bovine liver, porcine muscle, kidney vivo. Whole tissues prewarmed (35°C)...
BACKGROUND Gallbladder cancer is the most common malignancy of biliary tract. Neoadjuvant chemotherapy (NACT) has improved overall survival by enabling R0 resection. Currently, there no consensus guidelines for neoadjuvant therapy in gallbladder cancer. As investigations continue to analyze regimen and benefit NACT ongoing care patients, we examined American College Surgeons National Surgical Quality Improvement Program (NSQIP) database determine if was higher morbidity among group within...
Resection of hepatic metastasis from neuroendocrine tumors (NETs) improves quality life and prolongs 5-year survival. Ablation can be utilized with surgery to achieve complete resection. Although several studies report long-term outcomes for patients undergoing ablation, none have explored perioperative effects ablation in metastatic NETs.
Pancreatic adenocarcinoma is currently the fourth leading cause of cancer-related deaths in United States. In patients with "borderline resectable" disease, current National Comprehensive Cancer Center guidelines recommend use neoadjuvant chemoradiation prior to a pancreaticoduodenectomy. Although radiotherapy may improve negative margin resection rate, it theorized that its administration increases operative times and complexity.To investigate association between 30-d morbidity mortality...
TPS10607 Background: Pancreatic adenocarcinoma (PC) has a persistently high mortality as it presents in the advanced stages and largely not benefited from genomic immunotherapeutic revolutions oncology. Improvements screening to detect early stage cancers are therefore urgently needed. Screening studies such those International CAPS Consortium have demonstrated improved survivals hereditary risk individuals. In sporadic population, individuals with new-onset diabetes (NOD) or long-standing...