- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Healthcare Decision-Making and Restraints
- Cancer Treatment and Pharmacology
- Respiratory Support and Mechanisms
- Family and Patient Care in Intensive Care Units
- Airway Management and Intubation Techniques
- Nosocomial Infections in ICU
- Alcoholism and Thiamine Deficiency
- Cardiac Arrest and Resuscitation
- Pain Management and Treatment
- Thermal Regulation in Medicine
- Tracheal and airway disorders
- Laser Applications in Dentistry and Medicine
- Intracerebral and Subarachnoid Hemorrhage Research
- Medicinal Plants and Bioactive Compounds
- Pain Management and Opioid Use
- Education, Healthcare and Sociology Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Infrared Thermography in Medicine
- Complementary and Alternative Medicine Studies
- Nursing Diagnosis and Documentation
- Emergency and Acute Care Studies
- Phytochemistry and Biological Activities
Erasmus MC
2013-2025
Erasmus University Rotterdam
2013-2015
Dollezhal Research and Development Institute of Power Engineering
2011-2012
Abstract Background The role of haloperidol as treatment for ICU delirium and related symptoms remains controversial despite two recent large controlled trials evaluating its efficacy safety. We sought to determine whether when compared placebo in critically ill adults with reduces days coma improves delirium-related sequelae. Methods This multi-center double-blind, placebo-controlled randomized trial at eight mixed medical-surgical Dutch ICUs included (Intensive Care Delirium Screening...
ABSTRACT Background Delirium is a common form of vital organ dysfunction in intensive care unit (ICU) patients and associated with poor outcomes. Adherence to guideline recommendations pertaining delirium still suboptimal. Aims We performed survey aimed at identifying barriers for implementation that should be addressed tailored intervention targeted improved ICU adherence. Design The was conducted among professionals. Methods An online 360 health professionals (nurses, physicians...
Implementation of delirium guidelines at ICUs is suboptimal. The aim was to evaluate the impact a tailored multifaceted implementation program ICU on processes care and clinical outcomes draw lessons regarding guideline implementation.A prospective multicenter, pre-post, intervention study.ICUs in one university hospital five community hospitals.Consecutive medical surgical critically ill patients were enrolled between April 1, 2012, February 2015.Multifaceted, three-phase (baseline,...
Delirium in critically ill patients has a strong adverse impact on prognosis. In spite of its recognized importance, however, delirium screening and treatment procedures are often not accordance with current guidelines. This implementation study is designed to assess barriers facilitators for guideline adherence next develop multifaceted tailored strategy. Effects this strategy as well important clinical outcomes will be described. Current practices deviations assessed prospective baseline...
Objective We aimed to explore: the exposure of healthcare workers a delirium guidelines implementation programme; effects on guideline adherence at intensive care unit (ICU) level; impact knowledge and barriers, experiences with implementation. Design A mixed-methods process evaluation prospective multicentre study. Setting Six ICUs. Participants 4449 adult ICU patients 500 professionals approximately. Intervention tailored programme. Main outcome measure Adherence recommendations level...
Introduction Delirium in critically ill adults is associated with prolonged hospital stay, increased mortality and greater cognitive functional decline. Current practice guideline recommendations advocate the use of non-pharmacological strategies to reduce delirium. The routine scheduled haloperidol treat delirium not recommended given a lack evidence regarding its ability resolve nor improve relevant short-term longer-term outcomes. This study aims evaluate efficacy safety for treatment...
The prognostic implication of delirium subtypes in critically ill medical and surgical patients is scarcely investigated. objective was to determine how are associated with hospital mortality other clinical outcomes. We performed a secondary analysis on data from prospective multicenter study aimed at implementation delirium-oriented measures, conducted between 2012 2015 Netherlands. included adults (≥ 18 years) admitted the or intensive care unit (ICU). Exclusion criteria were neurological...
As part of a multicenter prospective study on barriers and facilitators for implementation protocolled care delirious critically ill patients, we aimed to describe current practices in delirium management representative cohort ICU patients.
The study aims at demonstrating the efficiency of phytotherapy in macroprolactinoma downsizing. comparison phytotherapeutic (PT) leant on medical records submitted by patients prior to PT launch, indicating diagnosis established based outcome nuclear magnetic resonance imaging (NMRI) and/or computed tomography (CT) affected site and bringing results field-of-vision examination hormonal status determination. insight into documentation reference provided information tumour size prolactin...
The beliefs, knowledge and practices regarding ICU delirium among professionals may vary. This interfere with the implementation of Dutch Delirium guideline. We aimed to get insight into potential barriers facilitators for guideline that help find an effective strategy.
The study aims at demonstrating the efficiency of phytotherapy in regulation prolactin levels patients diagnosed with pituitary macroprolactinoma. made use workup outcomes submitted by treating healthcare facilities where were first macroprolactinomas based on diagnostic imaging (MRI and/or CT), laboratory workup, and hormone status estimation. data reference served as baseline for a comparative follow-up phytotherapeutic terms comparison medical obtained prior to those following herbal...