A5061662401- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Heterotopic Ossification and Related Conditions
- Eosinophilic Disorders and Syndromes
- Endometrial and Cervical Cancer Treatments
- Chronic Myeloid Leukemia Treatments
- Management of metastatic bone disease
- Palliative Care and End-of-Life Issues
- Cervical Cancer and HPV Research
- Kruppel-like factors research
- Colorectal and Anal Carcinomas
- Interprofessional Education and Collaboration
- Autoimmune Neurological Disorders and Treatments
- Advances in Oncology and Radiotherapy
- Systemic Sclerosis and Related Diseases
- Colorectal Cancer Surgical Treatments
- Effects of Radiation Exposure
- Angiogenesis and VEGF in Cancer
- Chemotherapy-related skin toxicity
- Complementary and Alternative Medicine Studies
- Geriatric Care and Nursing Homes
- Inflammatory Biomarkers in Disease Prognosis
- Pelvic and Acetabular Injuries
- Biomarkers in Disease Mechanisms
- Intraperitoneal and Appendiceal Malignancies
- Peripheral Neuropathies and Disorders
University of California, Irvine
2019-2024
University of California, San Diego
2019-2024
UC San Diego Health System
2020
Chronic inflammation is integral to myeloproliferative neoplasm (MPN) pathogenesis. JAK inhibitors reduce cytokine levels, but not without significant side effects. Nutrition a low-risk approach and ameliorate symptoms in MPN. We performed randomized, parallel-arm study determine the feasibility of an education-focused Mediterranean diet intervention among patients with
Background: Hematologic toxicity is a critical problem limiting treatment delivery in cancer patients undergoing concurrent chemoradiotherapy. However, the extent to which anatomic variations radiation dose limit chemotherapy poorly understood. A unique natural experiment arises with head and neck cervical cancer, who frequently undergo identical but receive different regions of body. Methods: In this longitudinal cohort study, we compared hematologic bone marrow compensatory response 148...
ABSTRACT Purpose Chronic inflammation is integral to Myeloproliferative Neoplasm (MPN) pathogenesis. JAK inhibitors reduce cytokine levels, but not without significant side effects. Nutrition a low-risk approach and ameliorate symptoms in MPN. We performed randomized, parallel-arm study determine the feasibility of an education-focused Mediterranean diet intervention among MPN patients. Experimental Design randomly assigned participants either or standard US Dietary Guidelines for Americans...
<p>Patients with MPN can adopt a Mediterranean eating pattern dietician counseling and education. <b>A,</b> Percentage of participants MEDAS scores ≥8 at each timepoint orange shaded area depicting the active intervention period. <b>B,</b> Participant responses to feasibility question during period, green represents participant who met benchmark HEI-2015 (<b>C</b>) was calculated from 24-hour diet recall, for were averaged pre-intervention (weeks...
<p>Supplementary Figure 3. Changes in JAK2V617F allele burden over time.</p>
<p>Supplementary Figure 1. Complete blood count (CBC) data from participants.</p>
<p>Baseline and week 9 BMI. Baseline BMI was calculated using height weight at enrollment, with no significant differences between USDA MED groups. Weight followed throughout the study, changes in were observed either group.</p>
<p>Supplementary Figure 2. Changes in hsCRP during the study</p>
<p>Surveys used in the study</p>
<p>Energy intake, fiber and percentage of calories from carbohydrates, sugar, protein, fat calculated 24-hour diet recalls. Data are represented as mean ± SD</p>
<div>AbstractPurpose:<p>Chronic inflammation is integral to myeloproliferative neoplasm (MPN) pathogenesis. JAK inhibitors reduce cytokine levels, but not without significant side effects. Nutrition a low-risk approach and ameliorate symptoms in MPN. We performed randomized, parallel-arm study determine the feasibility of an education-focused Mediterranean diet intervention among patients with MPN.</p>Experimental Design:<p>We randomly assigned MPN either or standard...
<p>NUTRIENT study design.</p>
<p>Demographics of study cohort</p>
<p>Fecal microbiome composition. <b>A,</b> A line plot displaying the microbial diversity, as measured by Shannon index, of individuals over time. <b>B,</b> composition The <i>y</i>-axis is first principal coordinate produced Bray–Curtis dissimilarity ordination microbiome. In both and B, orange shaded area depicts active intervention period SE represented error bars.</p>
<p>Demographics of study cohort</p>
<p>NUTRIENT study design.</p>