A5016475638- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Pain Management and Opioid Use
- Economic and Financial Impacts of Cancer
- Bladder and Urothelial Cancer Treatments
- Cancer-related cognitive impairment studies
- Family Support in Illness
- Palliative Care and End-of-Life Issues
- Brain Metastases and Treatment
- Lung Cancer Diagnosis and Treatment
- Opioid Use Disorder Treatment
- Radiomics and Machine Learning in Medical Imaging
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Risks and Factors
- Cancer survivorship and care
- Interpreting and Communication in Healthcare
- Childhood Cancer Survivors' Quality of Life
- Colorectal Cancer Screening and Detection
- Cancer, Lipids, and Metabolism
- Assisted Reproductive Technology and Twin Pregnancy
- Lipoproteins and Cardiovascular Health
- COVID-19 and healthcare impacts
- Patient Satisfaction in Healthcare
- Head and Neck Cancer Studies
Duke University
2022-2025
University of California, San Diego
2018-2024
Clinical Research Institute
2024
Moores Cancer Center
2021-2022
Optum (United States)
2022
VA San Diego Healthcare System
2021
Veterans Health Administration
2021
UC San Diego Health System
2019-2020
San Diego State University
2019
Oncology rapidly shifted to telemedicine in response the COVID-19 pandemic. Telemedicine can increase access healthcare, but recent research has shown disparities exist with use during This study evaluated health associated uptake pandemic among cancer patients a tertiary care academic medical center.This retrospective cohort adult who received outpatient oncology within healthcare system between January and September 2020. We used multivariable mixed-effects logistic regression models...
<h3>Importance</h3> Researchers often analyze cancer registry data to assess for differences in survival among treatments. However, the retrospective, nonrandomized design of these analyses raises questions about study validity. <h3>Objective</h3> To examine extent which comparative effectiveness using observational produce results concordant with those randomized clinical trials. <h3>Design, Setting, and Participants</h3> In this study, a total 141 trials referenced National Comprehensive...
Importance Atrial fibrillation (AF) is the most common, chronic, cardiac arrythmia in older US adults. It not known whether AF independently associated with increased risk of retinal stroke (central artery occlusion), a subtype ischemic that causes severely disabling visual loss cases and harbinger further vascular events. Objective To determine there an association between stroke. Design, Setting, Participants This retrospective cohort study was performed July 2023 May 2024 using...
<h3>Importance</h3> There is concern that African American men with low-risk prostate cancer may harbor more aggressive disease than non-Hispanic White men. Therefore, it unclear whether active surveillance a safe option for <h3>Objective</h3> To compare clinical outcomes of and managed surveillance. <h3>Design, Setting, Participants</h3> Retrospective cohort study in the US Veterans Health Administration Care System diagnosed between January 1, 2001, December 31, 2015, The date final...
Abstract Background Although opioids play a critical role in the management of cancer pain, ongoing opioid epidemic has raised concerns regarding their persistent use and abuse. We lack data-driven tools oncology to understand risk adverse opioid-related outcomes. This project seeks identify clinical factors create score help patients at Methods Within cohort 106 732 military veteran survivors diagnosed between 2000 2015, we determined rates posttreatment use, diagnoses abuse or dependence,...
Pancreatic cancer is an aggressive malignancy with patients often experiencing nonspecific symptoms before diagnosis. This study evaluates a machine learning approach to help identify early-stage pancreatic from clinical data within electronic health records (EHRs).From the Optum deidentified EHR set, we identified (n = 3,322) and late-stage 25,908) cases over 40 years of age diagnosed between 2009 2017. Patients were matched noncancer controls (1:16 match). We constructed prediction model...
Background: Active surveillance (AS) is a safe treatment option for men with low-risk, localized prostate cancer. However, the safety of AS patients intermediate-risk cancer remains unclear. Patients and Methods: We identified NCCN-classified low-risk favorable unfavorable diagnosed between 2001 2015 initially managed in Veterans Health Administration. analyzed progression to definitive treatment, metastasis, cancer–specific mortality (PCSM), all-cause using cumulative incidences...
Melanoma is a very dangerous type of skin cancer that needs new ways to be found so it can treated quickly. The goal this study create better find melanoma by combining mixed Convolutional Neural Networks (CNN) and Autoencoder models with in-depth data analysis. This will make identification more accurate reliable. chosen method takes advantage deep learning techniques are designed work well image-based classification tasks. used dataset from the Skin Cancer MNIST: HAM10000 for work. It has...
The COVID-19 pandemic disrupted cancer clinical trials, prompting sponsors to adopt decentralized trial (DCT) elements ensure patient safety and continuity. Supported by FDA emergency guidance, the Oncology Center of Excellence, in collaboration with Clinical Trials Transformation Initiative (CTTI), conducted an assessment DCT trials leading approval during pandemic. Between December 6, 2022, January 17, 2023, CTTI collected survey data from about used response pandemic, implementation...
Minority race and lower socioeconomic status are associated with rates of opioid prescription undertreatment pain in multiple noncancer healthcare settings. It is not known whether these differences prescribing exist among patients undergoing cancer treatment.
Background: Patients with advanced esophageal cancer often experience pain and dysphagia, yet the optimal palliative management remains unclear. This retrospective study evaluated outcomes adverse effects of radiotherapy (RT) compared stenting among a cohort U.S. veterans metastatic cancer. Methods: We identified 1,957 in United States who received RT to esophagus or stenting, assessed risks severe effects, including fistula formation, perforation, obstruction, hemorrhage, esophagitis....
Muscle-invasive bladder cancer (MIBC) remains undertreated despite multiple potentially curative options. Both radical cystectomy (RC) with or without neoadjuvant chemotherapy and trimodal therapy (TMT), including transurethral resection of tumor followed by chemoradiotherapy, are standard treatments. To evaluate real-world clinical outcomes RC (RC-NAC), NAC, TMT National Comprehensive Cancer Network guideline–preferred radiosensitizing cisplatin mitomycin-C 5-fluorouracil (pTMT),...
Background There is no consensus on the association between use of androgen deprivation therapy (ADT) and risk developing depression. This study investigated ADT development depression, outpatient psychiatric services, inpatient suicide in a homogeneous group men with prostate cancer (PC) treated definitive radiation (RT) after controlling for multiple sources selection bias. Methods was retrospective, observational cohort 39,965 veterans PC who were RT diagnosed by US Department Veterans...
This cohort study examines the association of androgen deprivation therapy with dementia in male veterans prostate cancer who receive definitive radiotherapy.
PURPOSE Treatment decisions about localized prostate cancer depend on accurate estimation of the patient’s life expectancy. Current and noncancer survival models use a limited number predefined variables, which could restrict their predictive capability. We explored technique to create more comprehensive prediction using insurance claims data from large administrative set. These contain substantial information medical diagnoses procedures, thus may provide broader reflection each health....
More Americans are being screened for and more surviving colorectal cancer due to advanced treatments better quality of care; however, these benefits not equitably distributed among diverse or older populations. Differential care delivery outcomes driven by multiple factors, including access timely treatment that comes from high-quality coordination. Providers help ensure such coordinated care, which includes referrals specialists. Variation in between providers can also result differences...
Cancer patients frequently utilize the emergency department (ED) for a variety of diagnoses both related to and unrelated their cancer, yet ED outcomes cancer are not well documented. This study sought define risks identify predictors inpatient admission hospital mortality among presenting ED.We utilized National Emergency Department Sample with without diagnosis between January 2016 December 2018. We used multivariable mixed-effects logistic regression models assess influence on after visit...
Abstract Objective To evaluate risks of preterm birth (PTB) and severe maternal morbidity (SMM) in female survivors adolescent young adult cancer assess comorbidity as a potential mechanism. determine whether associations differ by use assisted reproductive technology (ART). Design Retrospective cohort. Setting Commercially insured females the USA. Sample Females with live births from 2000–2019 within de‐identified US administrative health claims data set. Methods Log‐binomial regression...