A5056463375- Economic and Financial Impacts of Cancer
- Multiple Myeloma Research and Treatments
- Chronic Myeloid Leukemia Treatments
- Medication Adherence and Compliance
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Diabetes Management and Research
- Health Systems, Economic Evaluations, Quality of Life
- Atrial Fibrillation Management and Outcomes
- Diabetes Treatment and Management
- Cancer Treatment and Pharmacology
- Bone health and treatments
- Lung Cancer Treatments and Mutations
- Neutropenia and Cancer Infections
- Acute Myeloid Leukemia Research
- Healthcare Policy and Management
- Childhood Cancer Survivors' Quality of Life
- Pancreatic function and diabetes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Opioid Use Disorder Treatment
- Radiopharmaceutical Chemistry and Applications
- Mental Health Treatment and Access
- HIV, Drug Use, Sexual Risk
- Breast Cancer Treatment Studies
- Pharmaceutical Economics and Policy
UnitedHealth Group (United States)
2022-2024
Optum (United States)
2014-2023
Texas Christian University
2023
Mayo Clinic in Arizona
2021
Twin Cities Orthopedics
2019
Amgen (United States)
2015
Therapeutics Clinical Research
2015
Ibero American University
2015
HealthInsight
2011-2012
United BioSource Corporation (United Kingdom)
2012
OBJECTIVE: The authors determined the costs associated with generalized social anxiety disorder in a managed care setting. METHOD: A three-phase mail and telephone survey was conducted from July to October 1998 two outpatient clinics of large health maintenance organization (HMO). assessed direct costs, indirect health-related quality life, clinical severity disorder, both alone comorbid psychopathology. RESULTS: weighted prevalence rate current 8.2%. In past year, only 0.5% subjects had...
Common mental disorders are often not identified in primary care settings.To evaluate the validity and clinical utility of a telephone-assisted computer-administered version Primary Care Evaluation Mental Disorders (PRIME-MD), brief questionnaire interview instrument designed to identify psychiatric patients.Comparison diagnoses obtained by computer over telephone using interactive voice response (IVR) technology vs those trained clinician Structured Clinical Interview for DSM-IV [Diagnostic...
<h3>Background</h3> Expanding access to high-quality depression treatment will depend on the balance of incremental benefits and costs. We examine cost-effectiveness an organized management program for high utilizers medical care. <h3>Methods</h3> Computerized records at 3 health maintenance organizations were used identify adult patients with outpatient visit rates above 85th percentile 2 consecutive years. A 2-step screening process identified current depressive disorders, who not in...
Because treatments for bipolar disorder include a growing number of psychotropic agents, the authors evaluated polytherapy and adherence to treatment among U.S. patients with disorder.National health plan claims data (2000-2004) were used identify diagnosed as having who had continuous benefits not been prescribed medication six months or more. The study compared drugs dispensed these initially at one year characterized adherent mood-stabilizers.A total 7,406 disorder: I (55%), II (15%),...
PURPOSE This pilot study examined the ability to operationalize collection of real-world data explore potential use end points extracted from diverse health care organizations and assess how these relate similar in clinical trials for immunotherapy-treated advanced non–small-cell lung cancer. PATIENTS AND METHODS Researchers six followed a common protocol using administrative claims electronic records points, including overall survival (rwOS), time next treatment, treatment discontinuation...
<h3>Abstract</h3> <h3>Objective</h3> To describe trends in the rate and daily dose of opioids used among commercial Medicare Advantage beneficiaries from 2007 to 2016. <h3>Design</h3> Retrospective cohort study administrative claims data. <h3>Setting</h3> National database medical pharmacy for commercially insured United States. <h3>Participants</h3> 48 million individuals with any period insurance coverage between 1 January 31 December 2016, including beneficiaries, aged 65 years over,...
<h3>Background:</h3> While previous studies have compared medical utilization between depressed and nondepressed patients, we conducted a study that focused specifically on patients who had history of high expenditures. <h3>Methods:</h3> This was designed to determine whether positive screen for depression is predictive continued Medical data were obtained 50 000 enrolled in the Dean Care health maintenance organization 2 consecutive years. Consistent utilizers identified based costs (paid...
Myelosuppressive chemotherapy can lead to dose-limiting febrile neutropenia. Prophylactic use of recombinant human G-CSF such as daily filgrastim and once-per-cycle pegfilgrastim may reduce the incidence This comparative study examined effect versus on risk hospitalization.This retrospective United States claims analysis utilized 2004-2009 data for filgrastim- pegfilgrastim-treated patients receiving non-Hodgkin's lymphoma (NHL) or breast, lung, ovarian, colorectal cancers. Cycles in which...
Create a timeline of diagnosis and treatment for IPF in the US.A retrospective analysis was performed collaboration with OptumLabs Data Warehouse using an administrative claims database Medicare Fee Service beneficiaries. Adults 50 over were included (2014 to 2019).To focus on IPF, following diagnoses excluded: post-inflammatory fibrosis, hypersensitivity pneumonitis, rheumatoid arthritis, sarcoidosis, scleroderma, connective tissue disease.Data collected from periods prior, during, initial...
Abstract Background. Treatment of multiple myeloma has dramatically improved with the introduction bortezomib (BOR), thalidomide (THAL), and lenalidomide (LEN). Studies assessing health care costs, particularly economic burden on patients, are limited. We conducted a claims-based, retrospective analysis total costs as well patient (patient out-of-pocket number ambulatory/hospital visits) associated BOR/THAL/LEN treatment versus other therapies (OTHER). Methods. episodes starting between...
The purpose of this study was to evaluate the potential collective opportunities and challenges transforming real-world data (RWD) evidence for clinical effectiveness by focusing on aligning analytic definitions oncology end points. Patients treated with a qualifying therapy advanced non-small cell lung cancer in frontline setting meeting broad eligibility criteria were included reflect population. Although trend toward improved outcomes patients receiving PD-(L)1 over standard chemotherapy...
The study examined the impact of identifying and treating depression among patients who had a history high medical expenditures. Effects on service use, disability, quality life were measured.A total 786 users services from two primary care clinics an equal number randomly selected not screened for using Medical Outcomes Study (MOS) screen. High-user positive subsequently seen by their physician diagnostic interview. 20 with confirmed diagnosis offered open-label antidepressant treatment six...
Abstract Background The role of biologic therapies in the treatment rheumatoid arthritis has expanded, but dosing patterns first versus subsequent lines therapy have not been thoroughly explored. Methods In order to describe agent utilization among patients with arthritis, health care claims data on use abatacept, rituximab, or anti-tumor necrosis factor (TNF) agents etanercept, adalimumab, and infliximab first- subsequent-line settings were used form patient cohorts. Variables included:...
Background This study aimed to compare percutaneous left atrial appendage occlusion (LAAO) with non‐vitamin K antagonist oral anticoagulants among patients fibrillation. Methods and Results Using a US administrative database, 562 850 fibrillation were identified, whom 8397 treated LAAO 554 453 between March 13, 2015 December 31, 2018. Propensity score overlap weighting was used balance baseline characteristics. The primary outcome composite end point of ischemic stroke or systemic embolism,...
This study aimed to estimate incidence, cost per episode of care, and US population burden cervical intraepithelial neoplasia (CIN).For women continuously enrolled in a health plan from January 1, 1999 December 31, 2004, medical claims were used identify potential CIN diagnosis. Presence grade (CIN 2,3, or no CIN) verified records for randomly selected subset (n = 254). Incidence, costs, calculated.Annual incidence 1 2,3 was 1.6 1.2 1,000 women, respectively. Incidence highest among aged 21...
To assess 12-month healthcare resource utilization and costs associated with upper gastrointestinal (UGI) bleeding events.Patients hospitalized a UGI event were identified in US national health-plan claims data (1999-2003) propensity matched to control patients without the same health plan. Matching criteria included age, gender, index date, Charlson Comorbidity Index score, geographic region, prior medical utilization.A total of 9,033 UGI-bleed 579,018 met inclusion criteria, yielding 4,651...