- Cancer Treatment and Pharmacology
- Cancer survivorship and care
- LGBTQ Health, Identity, and Policy
- Advanced Breast Cancer Therapies
- Cancer Risks and Factors
- Oral Health Pathology and Treatment
- Cancer-related cognitive impairment studies
- Reproductive Biology and Fertility
- BRCA gene mutations in cancer
- Childhood Cancer Survivors' Quality of Life
- Hair Growth and Disorders
- Lung Cancer Treatments and Mutations
- Global Cancer Incidence and Screening
- Otitis Media and Relapsing Polychondritis
- Chemotherapy-related skin toxicity
- Economic and Financial Impacts of Cancer
- Frailty in Older Adults
- PARP inhibition in cancer therapy
- Cancer Immunotherapy and Biomarkers
- Male Breast Health Studies
- Music Therapy and Health
- Reproductive Health and Technologies
- Breast Implant and Reconstruction
- Sinusitis and nasal conditions
- Medicinal plant effects and applications
Mayo Clinic in Arizona
2017-2025
Mayo Clinic
2017-2024
WinnMed
2022-2024
Office of Diversity and Inclusion
2023
American Society of Clinical Oncology
2023
American Cancer Society
2023
Saint Luke's Hospital
2020-2022
St. Vincent's Medical Center
2021
St. Luke's Hospital
2021
University of Missouri–Kansas City
2021
In the United States, one in 196 women is diagnosed with breast cancer under age of 40 years. Adolescents and young adults (AYAs), 15-39 years at diagnosis, experience a number unique challenges when confronting cancer. The incidence invasive has increased among AYA States since 2004, most this change due to an increase distant disease. AYAs are more likely than older present aggressive subtypes advanced disease, they often require systemic staging diagnosis. Clinical trials should be...
Accurate, patient-centred evaluation of physical function in patients with cancer can provide important information on the functional impacts experienced by both from disease and its treatment. Increasingly, digital health technology is facilitating providing new ways to measure symptoms function. There a need characterise longitudinal measurement characteristics assessments, including clinician-reported outcome, patient-reported ported outcome (PRO), performance tests wearable data, inform...
We report here a second case of patient with hemophagocytic lymphohistiocytosis (HLH) treated the JAK inhibitor ruxolitinib as first-line treatment. HLH is syndrome extreme but ineffective immune response driven by hyperactivation CD8 T-cells and macrophages, resulting in infiltration tissues hemophagocytosis, subsequent multi-organ failure. The liver, spleen, bone marrow are primarily affected cytopenias. divided broadly into primary secondary forms. form heterogeneous group genetic...
Background Sexual and gender minority individuals face numerous cancer‐related inequities, many of which appear to be underreported. However, the best authors’ knowledge, no one has assessed rates acquisition sexual orientation identity (SOGI) data within community oncology settings. Methods Community practices that were part NCI Oncology Research Program (NCORP) network asked whether they routinely collected SOGI information coded this in their electronic medical records. The proportion...
PURPOSE Routine collection of sexual orientation (SO) and gender identity (GI; collectively SOGI) in cancer clinics advances care equity. METHODS In 2022, NCI Community Oncology Research Program (NCORP) practice groups were asked about routine SOGI data the electronic health record. The proportions reporting SO and/or GI calculated, group characteristics assessed for associations. RESULTS Of 271 nationwide, 42% (n = 112) collect data, 58% 157) 35% 96) both. multivariate analyses, was...
Over 50% of households in the United States have at least one musician-many musicians are also breast cancer survivors. This group has not been well studied, and given level fine sensory-motor skill required for musicianship, we hypothesized that experience unique manifestations treatment toxicities. A nine-item Musical Toxicity Questionnaire (MTQ) was distributed to patients who had consented participate Mayo Clinic Breast Cancer Registry. The MTQ screened participants by asking if they...
524 Background: Antiangiogenic tyrosine kinase inhibitors (TKIs) play a key role in treating renal cell carcinoma and other solid organ malignancies, but TKIs cause bothersome side effects that frequently necessitate dose reductions or treatment holds. Olanzapine has been useful for palliating symptoms from classical chemotherapies advanced cancer, its effect on TKI-related is largely unknown. This retrospective study aimed to estimate the efficacy of olanzapine TKI-induced nausea, vomiting,...
Background: Patients who experience homelessness manifest poor cancer outcomes, often because of treatment delays. Few studies have used mixed methods to learn what happens at the patient and health care staff level explain these Methods: This single-institution, multi-site study interrogated entire medical record system (thousands patients annually) for diagnoses from January 1, 2019, through October 10, 2023. Records were abstracted relevant quantitative qualitative data; rigorous analyze,...
11145 Background: T-DXd is increasingly used in mBC. A toxicity of special interest interstitial lung disease/pneumonitis (ILD), occurring 10-15% pts the DESTINY-Breast trials, and with potential lower incidence/severity earlier line settings [Krop et al, ASCO 2023]. However, routine practice, may be more heavily pre-treated mBC previously exposed to other antibody-drug conjugates (ADC) [Premji al SABCS We evaluated related ILD at Mayo Clinic. Methods: retrospectively identified who received...
Integrative therapies such as yoga are potential treatments for many psychological and physical symptoms that occur during and/or after treatment cancer. The purpose of the current study was to evaluate patient-perceived benefit commonly experienced by breast cancer survivors.1,049 survivors who had self-reported use on a follow up survey, in an ongoing prospective Mayo Clinic Breast Disease Registry (MCBDR), received additional mailed yoga-focused survey asking about impact variety...
This study sought to understand the patients' perspective of what contributes an absence discussions sexual orientation (SO), gender identity (GI), and health in cancer care.Patients were recruited from oncology, gynecology, a transition clinic participate semistructured interviews, which analyzed with qualitative methods.A total 25 patients interviewed, shedding light on 2 themes. The first was that these conversations are important but infrequent. One patient explained, "…. we know people...
End of life is difficult for all patients but sexual and gender minorities (SGM) are prone to isolation loneliness, especially if their SGM status unknown or unaccepted. In oncology clinics, where goals care discussions about end integral frequent, querying health particular importance. The American Society Clinical Oncology recently released a position statement that called greater focus on populations with the goal reducing eventually eliminating disparities in cancer within this group. An...
Highlights•Fertility preservation counseling is an unmet need in women undergoing hematopoietic cell transplantation (HCT).•The rate of fertility lower than expected.•Assisted reproductive technologies are underutilized HCT.•Menstrual recovery rare but more likely after reduced-intensity conditioning.AbstractIatrogenic menopause with consequent infertility a major complication reproductive-age (HCT). Recent guidelines recommend discussion the possibility and options for as part informed...
Although national organizations advocate that health-care providers ask patients about sexual health and gender minority status-to learn, for example, side effects of treatment to understand patients' social support-these conversations often do not occur. This study explored providers' reasons having/not having these conversations.This single-institution recruited from medical oncology, hematology, radiation gynecology. Face-to-face interviews were recorded, transcribed, analyzed...
2][3][4][5] Improving the poorer cancer outcomes among TGD individuals is important.The first step to mitigating these disparities identifying people in electronic health record (EHR) and discussing individual needs preferences at point of care.The cancer-specific challenges adequately address them are noteworthy, 2,3 as highlighted following case.A 48-year-old nonbinary person with no contributory medical or family history was diagnosed a locally advanced, estrogen receptor-positive,...