A5090597964- Palliative Care and End-of-Life Issues
- Management of metastatic bone disease
- Advances in Oncology and Radiotherapy
- Patient-Provider Communication in Healthcare
- Pain Management and Opioid Use
- Childhood Cancer Survivors' Quality of Life
- Ethics in medical practice
- Cancer survivorship and care
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Streptococcal Infections and Treatments
- Spine and Intervertebral Disc Pathology
- Advanced Radiotherapy Techniques
- Medical Imaging and Pathology Studies
- Pharmacological Effects and Toxicity Studies
- Lung Cancer Treatments and Mutations
- Family Support in Illness
- Frailty in Older Adults
- Radiopharmaceutical Chemistry and Applications
- Central Venous Catheters and Hemodialysis
- COVID-19 and healthcare impacts
- Anesthesia and Pain Management
- Patient Dignity and Privacy
- Health Systems, Economic Evaluations, Quality of Life
- Esophageal and GI Pathology
- Delphi Technique in Research
University of California, Los Angeles
2019-2025
North Carolina State University
2024
Health Sciences Centre
2024
Sunnybrook Health Science Centre
2024
Leiden University
2024
Clemson University
2023
Weatherford College
2022
VA Greater Los Angeles Healthcare System
2022
University of Alabama
2021
Colorado State University
2021
We previously reported preoperative depression, anxiety, and pain were associated with greater pain, more utilization of healthcare resources, worse outcome 1 year after total knee arthroplasty. asked whether these outcomes persisted over time patients unexplained heightened early surgery ultimately satisfied. prospectively followed evaluated 83 (109 TKAs) 5 years postoperative. The mean age was 66 years; 55% women. Preoperative depression predicted lower Knee Society score mostly related to...
Abstract Navigating antibiotics at the end of life is a challenge for infectious disease (ID) physicians who remain deeply committed to providing patient-centered care and engaging in shared decision making. ID physicians, often see patients both inpatient outpatient settings maintain continuity with refractory or recurrent infections, are ideally situated provide guidance that aligns patients’ goals values. Complex communication skills, including navigating difficult emotions around...
709 Background: The Canopy Cancer Collective, a Learning Health Network (LHN) comprised of 14 pancreatic cancer centers across the U.S., set ambitious goals in 2023 to improve screening rates four key areas: clinical trial (from baseline 30% 100%), assessment enzyme replacement (37% care discussions (57% and palliative (30% 100%). This study aimed identify barriers facilitators influencing implementation these aims, with goal developing informed, actionable recommendations for future...
Pain from spinal metastases can result in significant impact to patients' quality of life. Conventional external beam radiation therapy (cEBRT) has long been shown be effective the pain control patients with metastases. With advancement therapy, stereotactic body (SBRT) increasingly adopted for treatment Multiple randomised controlled trials (RCT) have performed evaluate whether SBRT provides better relief compared cEBRT. Previous meta-analyses showed that significantly complete response at...
Background: Patients with advanced esophageal cancer often experience pain and dysphagia, yet the optimal palliative management remains unclear. This retrospective study evaluated outcomes adverse effects of radiotherapy (RT) compared stenting among a cohort U.S. veterans metastatic cancer. Methods: We identified 1,957 in United States who received RT to esophagus or stenting, assessed risks severe effects, including fistula formation, perforation, obstruction, hemorrhage, esophagitis....
Decision-makers need signals for action as the coronavirus disease 2019 (COVID-19) pandemic progresses. Our aim was to demonstrate a novel use of statistical process control provide timely and interpretable displays COVID-19 data that inform local mitigation containment strategies. Healthcare other industries study variation disaggregate purposes understanding behavior processes systems intervening on them. We developed charts at county city/neighborhood level within one state (California)...
Intra-articular corticosteroid injections are standard of care for managing joint pain secondary to osteoarthritis or rheumatoid arthritis but rarely used in haemophilic arthropathy. We have introduced and evaluated the efficacy safety ultrasound-guided relief patients with arthropathy.Ultrasound-guided intra-articular performed on haemophilia at UCSD between March 2012 January 2016 were analysed. Needle placement injection (40 mg triamcinolone; 3-5 mL lidocaine) musculoskeletal ultrasound...
An addendum of the ICH E9 guideline on Statistical Principles for Clinical Trials was released in November 2019 introducing estimand framework. This new framework aims to align trial objectives and statistical analyses by requiring a precise definition inferential quantity interest, that is, estimand. explicitly accounts intercurrent events, such as switching anticancer therapies analysis overall survival (OS), gold standard oncology. Traditionally, OS confirmatory studies is analyzed using...
An 8-year-old American Quarter Horse gelding was treated with extracorporeal hemoperfusion (HP) therapy for treatment of Clostridioides difficile (C. difficile) colitis-induced systemic inflammatory response syndrome (SIRS). The developed C. associated peracute colitis and severe SIRS as evidenced by a positive fecal PCR tachypnea, tachycardia, fever, neutropenia, altered mucous membrane color, hyperlactatemia. Concurrent acute kidney injury in the horse limited use routine anti-inflammatory...
Rising costs and a workforce talent shortage are two of the health care industry's most pressing challenges. In particular, serious illnesses often impose significant on individuals their families, which can place families at an increased risk for multigenerational economic deprivation or even illness–poverty trap. At same time, family caregivers acquire wide variety skills that neither these nor industry typically use. As marketable could be paired with many existing medical certifications,...
Background: Patient-controlled analgesia (PCA) is an effective approach to treat pain. However, data regarding patterns of PCA use for cancer pain are limited. The purpose this study was define the and related outcomes in hospitalized patients with cancer. Methods: We identified 90 admitted a single academic center who received nonsurgical, cancer-related survived discharge between January 2013 2014. Data collected included patient demographics, diagnosis, type pain, use, opioid-specific...