A5101682928- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Healthcare Policy and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatitis Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Glioma Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Hemodynamic Monitoring and Therapy
- Blood Pressure and Hypertension Studies
- Patient Satisfaction in Healthcare
- Management of metastatic bone disease
- Abdominal Surgery and Complications
- Liver Disease and Transplantation
- Patient-Provider Communication in Healthcare
- Viral-associated cancers and disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Primary Care and Health Outcomes
- Diversity and Career in Medicine
- Colorectal Cancer Treatments and Studies
- Economic and Financial Impacts of Cancer
- Gastric Cancer Management and Outcomes
- Aortic Disease and Treatment Approaches
- Palliative Care and End-of-Life Issues
- Educational Games and Gamification
Peking University
2022-2023
Boston Consulting Group (United States)
2019-2022
The Ohio State University Wexner Medical Center
2017-2022
University of California, San Diego
2020-2021
Northeastern University
2020
Johns Hopkins University
2017-2019
Johns Hopkins Medicine
2017-2019
The Ohio State University
2018
Loyola University Medical Center
2018
China Pharmaceutical University
2017
BACKGROUND: Intraoperative hypotension (IOH) occurs frequently during surgery and may be associated with organ ischemia; however, few multicenter studies report data regarding its associations adverse postoperative outcomes across varying hemodynamic thresholds. Additionally, no study has evaluated the association between IOH exposure among patients by various age groups. METHODS: A retrospective cohort was conducted 2008 2017 using intraoperative blood pressure from US electronic health...
Objective: To define and test “Textbook Outcome” (TO)—a composite measure for healthcare quality—among Medicare patients undergoing hepatopancreatic resections. Hospital variation in TO payments were analyzed. Background: Composite measures of quality may be superior to individual the analysis hospital performance. Methods: The Provider Analysis Review (MEDPAR) Inpatient Files reviewed identify who underwent pancreatic liver procedures between 2013 2015. was defined as: no postoperative...
Composite measures may be superior to individual for the analysis of hospital performance and quality surgical care.To determine incidence a so-called textbook outcome, composite measure care, among patients undergoing curative-intent resection intrahepatic cholangiocarcinoma.This cohort study involved an multinational, multi-institutional patient from 15 major hepatobiliary centers in North America, Europe, Australia, Asia who underwent cholangiocarcinoma between 1993 2015. Data was...
Although patient satisfaction is increasingly used to rate hospitals, it unclear how associated with health outcomes. We sought define the relationship of self-reported and outcomes.Retrospective cross-sectional analysis using regression analyses generalized linear modeling.Utilizing Medical Expenditure Panel Survey Database (2010-2014), patients who had responses survey questions related were identified.Among 9166 patients, representing 106 million was rated as optimal (28.2%), average...
Whilst intraoperative hypotension is associated with postoperative acute kidney injury (AKI), the link between and disease (AKD), defined as continuing renal dysfunction for up to 3 months after exposure, has not yet been studied.We conducted a retrospective multicentre cohort study using data from noncardiac, non-obstetric surgery extracted US electronic health records database. Primary outcome was association hypotension, at three MAP thresholds (≤75, ≤65, ≤55 mm Hg), following two AKD...
Abstract Background The postoperative period is critical for a patient’s recovery, and hypotension, specifically, associated with adverse clinical outcomes significant harm to the patient. However, little known about association between hypotension in patients intensive care unit (ICU) after non-cardiac surgery, morbidity mortality, specifically among who did not experience intraoperative hypotension. goal of this study was assess impact at various absolute hemodynamic thresholds (≤ 75, ≤ 65...
Background Aortic valve replacement (AVR) is a life‐saving treatment for patients with symptomatic severe aortic stenosis. We sought to determine whether transcatheter AVR has resulted in more equitable rate by race the United States. Methods and Results A total of 32 853 stenosis were retrospectively identified via Optum’s deidentified electronic health records database (2007–2017). rates non‐Hispanic Black White assessed year after diagnosis. Multivariate Fine‐Gray hazards models used...
Pancreatic cancer is an aggressive malignancy with patients often experiencing nonspecific symptoms before diagnosis. This study evaluates a machine learning approach to help identify early-stage pancreatic from clinical data within electronic health records (EHRs).From the Optum deidentified EHR set, we identified (n = 3,322) and late-stage 25,908) cases over 40 years of age diagnosed between 2009 2017. Patients were matched noncancer controls (1:16 match). We constructed prediction model...
BACKGROUND: Postoperative hypotension (POH) is associated with major adverse events. However, little known about the association of blood pressure thresholds and outcomes in postoperative patients without intraoperative (IOH) on general-care ward. We evaluated POH cardiac or cerebrovascular events (MACCE) IOH. METHODS: This retrospective analysis included 67,968 noncardiac patient-procedures (2008–2017) for discharged to ward mean arterial (MAP) readings, managed ≥48 hours postsurgery, no...
Background The effect of the histological subtype on prognosis patients undergoing surgery for colon cancer (CC) is not completely understood. Methods Surveillance, Epidemiology, and End Results (SEER) 2004–2014 database was used to compare long‐term outcomes resection classical adenocarcinoma (CA), mucinous (MUC), signet‐cell (SC). A total 153 317 (89%) had CA, 16 660 (10%) MUC while 1810 (1%) SC subtype. Patients with more frequently a poorly differentiated CC were likely present advanced...
We present DeepSeek-Coder-V2, an open-source Mixture-of-Experts (MoE) code language model that achieves performance comparable to GPT4-Turbo in code-specific tasks. Specifically, DeepSeek-Coder-V2 is further pre-trained from intermediate checkpoint of DeepSeek-V2 with additional 6 trillion tokens. Through this continued pre-training, substantially enhances the coding and mathematical reasoning capabilities DeepSeek-V2, while maintaining general Compared DeepSeek-Coder-33B, demonstrates...
The practice of palliative radiation therapy (RT) is based on extrapolation from adult literature. We evaluated patterns pediatric RT to describe regimens used identify opportunity for future pediatric-specific clinical trials.Six international institutions with expertise completed a 122-item survey evaluating patients ≤21 years old 2010 2015. Two use proton RT. Palliative was defined as treatment the goal symptom control or prevention immediate life-threatening progression.Of 3,225...
Game design is increasingly used in modern education to foster Computational Thinking (CT). Yet, it unclear how and if the game genre of student-designed games impact CT programming. We explore impacts development programming routines Scratch designed by 8th-grade students using a metrics-based approach (i.e., Dr. Scratch). Our findings show that designing particular (e.g., action, storytelling) development. observe, for instance, skills develop consolidate fast, after which can focus on...