Özgür Akgül

ORCID: 0000-0002-3762-3987
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About
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Research Areas
  • Inflammatory Biomarkers in Disease Prognosis
  • Acute Myocardial Infarction Research
  • Pancreatic and Hepatic Oncology Research
  • Cardiac Imaging and Diagnostics
  • Gallbladder and Bile Duct Disorders
  • Coronary Interventions and Diagnostics
  • Pancreatitis Pathology and Treatment
  • Cardiovascular Disease and Adiposity
  • Cardiac Valve Diseases and Treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cardiovascular Function and Risk Factors
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Adipokines, Inflammation, and Metabolic Diseases
  • Appendicitis Diagnosis and Management
  • Economic and Financial Impacts of Cancer
  • Cardiovascular Health and Disease Prevention
  • Intraperitoneal and Appendiceal Malignancies
  • Esophageal and GI Pathology
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Treatments and Studies
  • Heart Failure Treatment and Management
  • Systemic Sclerosis and Related Diseases
  • Thyroid Cancer Diagnosis and Treatment
  • Abdominal Surgery and Complications
  • Colorectal Cancer Surgical Treatments

Ankara Numune Eğitim ve Araştırma Hastanesi
2008-2024

Çankaya University
2024

Adnan Menderes University
2024

Sağlık Bilimleri Üniversitesi
2024

Ankara Bilkent City Hospital
2023

Bilkent University
2023

Memorial Ankara Hospital
2021

Burdur Mehmet Akif Ersoy Üniversitesi
2012-2020

The Ohio State University Wexner Medical Center
2018-2019

The Ohio State University
2018

Objective: To define and test “Textbook Outcome” (TO)—a composite measure for healthcare quality—among Medicare patients undergoing hepatopancreatic resections. Hospital variation in TO payments were analyzed. Background: Composite measures of quality may be superior to individual the analysis hospital performance. Methods: The Provider Analysis Review (MEDPAR) Inpatient Files reviewed identify who underwent pancreatic liver procedures between 2013 2015. was defined as: no postoperative...

10.1097/sla.0000000000003105 article EN Annals of Surgery 2018-11-29

Background Tramadol is an analgesic drug, and its mechanism of action believed to be mediated by the mu-opioid receptor. A further tramadol has been identified as blocking reuptake serotonin (5-HT). One most recently subtypes 5-HT receptor 5-HT7 Thus, authors aimed examine potential role serotonergic descending bulbospinal pathways spinal receptors compared with that 5-HT2A 5-HT3 in antinociceptive antihyperalgesic effects major active metabolite O-desmethyltramadol (M1) on phasic...

10.1097/aln.0b013e3181cd7920 article EN Anesthesiology 2010-02-17

Background: Chronic periodontitis (CP) and rheumatoid arthritis (RA) appear to share many pathologic features. Oxygen metabolism has an important role in the pathogenesis of both CP RA. The aim this study is evaluate relationship between these two chronic inflammatory diseases with regard antioxidant oxidant status. Methods: A total 80 participants were divided into four groups 20 each: group RA–CP (patients RA CP), (periodontally healthy patients RA), (systemically C systemically...

10.1902/jop.2011.110420 article EN Journal of Periodontology 2011-11-03

Abstract Aim To report, for the first time, incidence and prevalence of childhood Type 1 diabetes in Turkey using a nationwide registry. Methods Information on birth date, city birth, diagnosis date gender all patients with aged < 18 years were obtained from Turkish Social Security Institute period January 2011 to December 2013. Results There 17 175 prevalent cases over 3‐year period. The was 0.75/1 000 (95% CI 0.74–0.76) higher girls than boys (0.79 vs 0.72 /1 000; P 0.01). 2465 incident...

10.1111/dme.13063 article EN Diabetic Medicine 2016-01-27

Red blood cell distribution width (RDW), a marker of variation in the size circulating red cells, was evaluated patients with non-ST elevation myocardial infarction (NSTEMI) and unstable angina pectoris (UAP).Higher RDW is associated mortality general population, particularly those symptomatic cardiovascular disease, heart failure. We hypothesized that admission might be predictive adverse clinical outcomes for NSTEMI UAP.We prospectively enrolled 310 UAP (mean age 59.3±11.9 years; 236 men,...

10.1097/mca.0b013e3283564986 article EN Coronary Artery Disease 2012-06-27

Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy. We sought to examine the association between preoperative prognostic nutritional index (PNI) and long‐term overall survival among patients with ICC who underwent curative‐intent resection. Methods Patients hepatectomy for 1990 2015 were identified using international multi‐institutional database. Clinic‐pathological characteristics outcomes of PNI ≥ 40 <40 compared univariable multivariable analyses. Results...

10.1002/jso.25140 article EN Journal of Surgical Oncology 2018-08-06

We sought to determine the prognostic value of neutrophil lymphocyte ratio (NLR) in non-ST elevation myocardial infarction (NSTEMI) and unstable angina pectoris (UAP). A total 308 (mean age 59.22 ± 11.93) patients with NSTEMI UAP were prospectively evaluated. The study population was divided into tertiles based on admission NLR values. followed for clinical outcomes up 3 years after discharge. In Kaplan-Meier survival analysis, 3-year mortality 21.6% high versus 3% low-NLR group (P < .001)....

10.1177/1076029612465669 article EN Clinical and Applied Thrombosis/Hemostasis 2012-11-08

Background The effect of the histological subtype on prognosis patients undergoing surgery for colon cancer (CC) is not completely understood. Methods Surveillance, Epidemiology, and End Results (SEER) 2004–2014 database was used to compare long‐term outcomes resection classical adenocarcinoma (CA), mucinous (MUC), signet‐cell (SC). A total 153 317 (89%) had CA, 16 660 (10%) MUC while 1810 (1%) SC subtype. Patients with more frequently a poorly differentiated CC were likely present advanced...

10.1002/jso.25044 article EN Journal of Surgical Oncology 2018-03-25

Introduction. Nitric oxide (NO) and peroxynitrite (OONO—) are implicated in the pathophysiology of renal ischemia/reperfusion (I/R). The aim this study was to investigate compare efficiency S-methylisothiourea (SMT), an iNOS inhibitor, mercaptoethylguanidine (MEG), a scavenger peroxynitrite, on dysfunction injury induced by I/R rat kidney. Materials Methods. Thirty-two male Sprague-Dawley rats were divided into four groups: sham-operated, I/R, I/R+SMT, I/R+MEG. Rats given SMT (10 mg/kg ip)...

10.1080/08860220802213039 article EN Renal Failure 2008-01-01

Abstract Aim To assess bone mass in women with systemic sclerosis ( SS c) comparison to age and sex‐matched patients rheumatoid arthritis RA ), evaluate factors influencing mineral density BMD ). Methods Patients were consecutively recruited assessed for at the lumbar spine hip by dual‐energy X ‐ray absorptiometry DEXA ) using a densitometer. In c, extent of skin involvement, modified R odnan thickness score (m RSS M edsger disease severity index assessed. Results Forty‐three c 38...

10.1111/1756-185x.12242 article EN International Journal of Rheumatic Diseases 2013-11-28

Objective The aim of this study was to evaluate the prognostic value mean platelet volume (MPV) in patients with STEMI undergoing primary percutaneous coronary intervention (PCI).Methods We prospectively enrolled 495 consecutive patients. population divided into tertiles based on admission MPV values. high group (n = 148) defi ned as a third tertile (> 8.9), and low 347) included those lower two (≤ 8.9). Clinical characteristics, in-hospital six-month outcomes PCI were analysed.Results...

10.1080/ac.68.3.2983426 article EN Acta Cardiologica 2013-06-01

is a peer-reviewed open access academic journal that aims to guide clinical practice and improve diagnostic therapeutic skills of clinicians.WJGO covers topics concerning carcinogenesis, tumorigenesis, metastasis, diagnosis, prevention, prognosis, manifestations, nutritional support, molecular mechanisms, therapy benign malignant tumors the digestive tract.The current columns WJGO include editorial, frontier, advances, therapeutics field vision, mini-reviews, review, topic highlight, medical...

10.4251/wjgo.v9.i7.300 article EN cc-by-nc World Journal of Gastrointestinal Oncology 2017-01-01

Objective: Patients with resistant hypertension are at increased risk for cardiovascular events.Mean platelet volume (MPV) is an accepted biomarker of activation and considered as a factor disease.The aim this study was to determine whether MPV levels higher in hypertensive (RHTN) patients than controlled (CHTN) healthy normotensive controls. Materials Methods: 279 consecutive were included study.Patients divided into three groups: Resistant patient group [n=78; mean age 56.8±9.8;42 males...

10.5152/eurasianjmed.2015.43 article EN cc-by Eurasian Journal of Medicine 2015-03-04

Mean platelet volume to count (MPV/Plt) ratio has been demonstrated be a good indicator of long-term mortality in patients with non-ST-segment elevation myocardial infarction (NSTEMI). However, the prognostic value MPV/Plt ST-elevation (STEMI) is not reported.To determine whether on admission any predictive for major adverse cardiac events including short- and STEMI.In this prospective study, 470 STEMI who underwent primary percutaneous coronary intervention (PCI) were enrolled. The divided...

10.5603/kp.a2015.0179 article EN Kardiologia Polska 2015-09-14

A high SYNTAX score (SXscore) is a predictor of adverse outcomes for stable and unstable coronary syndromes. We aimed to examine whether SXscore will determine in-hospital clinical in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous intervention.A total 646 (mean age 56.1 ± 12.5; 516 males, 130 females) STEMI intervention were evaluated prospectively. The study population was divided into tertiles based on the values. (n=196) defined as value third...

10.1097/mca.0b013e3283599486 article EN Coronary Artery Disease 2012-09-26
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