A5002672995- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Diabetes Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Blood Coagulation and Thrombosis Mechanisms
- Acute Ischemic Stroke Management
- Vitamin K Research Studies
- Meta-analysis and systematic reviews
- Academic Writing and Publishing
- Genetic Neurodegenerative Diseases
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cardiac and Coronary Surgery Techniques
- Spinal Hematomas and Complications
- scientometrics and bibliometrics research
- Hemispheric Asymmetry in Neuroscience
- Growth Hormone and Insulin-like Growth Factors
- Atherosclerosis and Cardiovascular Diseases
- Mobile Health and mHealth Applications
- Vitamin C and Antioxidants Research
- Alcoholism and Thiamine Deficiency
University of Catania
1985-2025
Universitat de Barcelona
2024-2025
Hospital Clínic de Barcelona
2024-2025
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2024-2025
Policlinico Universitario di Catania
2021-2025
Ospedale Vincenzo Cervello
2013
University of Pisa
1989
The evolution of anticoagulation therapy, from vitamin K antagonists to the advent direct oral anticoagulants (DOACs) almost two decades ago, marks significant progress. Despite improved safety demonstrated in pivotal trials and post-marketing observations, persistent concerns exist, particularly regarding bleeding risk absence therapeutic indications specific subgroups or clinical contexts. Factor XI (FXI) has recently emerged as a contributor intraluminal thrombus formation growth, playing...
Abstract Background and aims Multiple anti-inflammatory drugs have been tested for secondary prevention after myocardial infarction (MI), giving mixed results questioning the efficacy of therapy. No head-to-head comparisons between performed. This study aimed to compare safety MI relative merits specific administration strategies. Methods Randomized trials therapy were identified. Primary endpoints trial-defined major adverse cardiovascular events (MACE) serious events. Secondary included...
Background Intracoronary provocation testing with acetylcholine (ACh) is helpful to diagnose and risk‐stratify patients ischemia nonobstructed coronary arteries (NOCA) myocardial infarction NOCA. This study explored potential sex‐related disparities on the prognostic significance of ACh provocative testing. Methods Consecutive NOCA those who underwent were enrolled. The primary end point was incidence major adverse cardiovascular cerebrovascular events at follow‐up. Co‐primary points angina...
When acute myocardial injury is found in a clinical setting suggestive of ischaemia, the event labelled as infarction (AMI), and absence coronary stenosis angiographically 50% or greater leads to working diagnosis with non-obstructive arteries (MINOCA). The initial MINOCA can be confirmed ruled out based on results subsequent investigations. This narrative review discusses downstream diagnostic approaches MINOCA, appraises strengths limitations invasive non-invasive investigations for this...
Abstract Periprocedural myocardial infarction (PMI) and injury, pertinent to both cardiac non-cardiac procedures, have gained increasing recognition in clinical practice. Over time, diverse definitions for diagnosing PMI been developed validated among patient populations undergoing coronary revascularization. However, this variety presents considerable challenges settings complicates the design interpretation of trials. The necessity accurately diagnose has spurred significant interest...
Single antiplatelet therapy (SAPT) and intensified antithrombotic regimens (prolonged dual [DAPT] or pathway inhibition [DPI]) are recommended for secondary prevention in patients who underwent percutaneous coronary intervention (PCI) after initial DAPT. We aimed to characterize eligibility such strategies explore what extent guidelines applied clinical practice. Patients PCI acute chronic syndrome completed DAPT were analyzed from a prospective registry. categorized into SAPT, prolonged...