A5049928748- Geochemistry and Geologic Mapping
- Drug Solubulity and Delivery Systems
- Remote Sensing and Land Use
- Powder Metallurgy Techniques and Materials
- Mineral Processing and Grinding
- Planetary Science and Exploration
- Granular flow and fluidized beds
- Water Quality Monitoring and Analysis
- Hydrocarbon exploration and reservoir analysis
- Space exploration and regulation
- Geological and Geophysical Studies
- Remote-Sensing Image Classification
- Soil Geostatistics and Mapping
- Microencapsulation and Drying Processes
- Remote Sensing in Agriculture
- Advanced Drug Delivery Systems
- Injection Molding Process and Properties
- Advanced Measurement and Detection Methods
- Infrared Target Detection Methodologies
- Spacecraft Design and Technology
- Satellite Image Processing and Photogrammetry
- Marine and fisheries research
- Geological Modeling and Analysis
- Rheology and Fluid Dynamics Studies
- Biochemical and Molecular Research
Long Island University
1970-1975
Defense Systems (United States)
1966
Navoximod (GDC-0919, NLG-919) is a small molecule inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), developed to treat the acquired immune tolerance associated with cancer. The primary objectives this study were assess navoximod's absolute bioavailability (aBA), determine mass balance and routes elimination [14 C]-navoximod, characterize metabolite profile.A phase 1, open-label, two-part was conducted in healthy volunteers. In Part subjects (n = 16) randomized receive oral (200 mg tablet)...
Ipatasertib (GDC-0068) is a potent, highly selective, small-molecule inhibitor of protein kinase B (Akt) being developed by Genentech/Roche as single agent and in combination with other therapies for the treatment cancers. To fully understand absorption, metabolism, excretion ipatasertib humans, an open-label study using 14C-radiolabeled was completed to characterize absolute bioavailability (period 1) mass balance metabolite profiling 2). In period 1, subjects were administered 200 mg oral...
Die filling is a crucial step in the pharmaceutical tablet manufacturing process. For industrial-scale production using rotary presses, suction typically employed due to its significant efficiency advantages over gravity filling. Despite widespread use, our understanding of process remains limited. Specifically, there insufficient comprehension how performance influenced by factors such as velocity, and properties powder materials. Building on previous research, this study aims further...
Understanding die filling behaviour of powders is critical in developing optimal formulation and processes various industries, such as pharmaceuticals fine chemicals. In this paper, forced analysed using a graphics processing unit (GPU) based discrete element method (DEM), for which powder feeder equipped with wired stirrer considered. The influences operating parameters, the initial bed height, speed, on performance are systematically explored. It shown that larger height leads to higher...
Die filling is a critical stage during powder compaction, which can significantly affect the product quality and efficiency. In this paper, forced feeder introduced attempting to improve performance of lab-scale die system. The process analysed with graphics processing units (GPU) enhanced discrete element method (DEM). Various stirrer designs are assessed for wide range settings (i.e., speed, speed) explore their influence on free-flowing powder. Numerical results show that filing novel...
The problem which faces photointerpreters is that of extracting the maximum amount military information from a certain set film data often consists only about two or three pieces simultaneous imagery. Usually, panchromatic, near infra red and thermal photography employed. It this photointerpreter required to obtain pertinent terrain characteristics as well location, strength disposition enemy.