A5006571320- Biomedical Text Mining and Ontologies
- Research Data Management Practices
- Genomics and Phylogenetic Studies
- scientometrics and bibliometrics research
- Genomics and Chromatin Dynamics
- Gene expression and cancer classification
- Bioinformatics and Genomic Networks
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Academic Publishing and Open Access
Drexel University
2018-2020
The biological interpretation of gene lists with interesting shared properties, such as up- or down-regulation in a particular experiment, is typically accomplished using ontology enrichment analysis tools. Given list genes, (GO) may return hundreds statistically significant GO results "flat" list, which can be challenging to summarize. It also difficult keep pace rapidly expanding knowledge, often daily changes any the over 47,000 ontologies that describe knowledge. GOATOOLS, Python-based...
Lysine methylation of histones and non-histone substrates by the SET domain containing protein lysine methyltransferase (KMT) G9a/EHMT2 governs transcription contributing to apoptosis, aberrant cell growth, pluripotency. The positioning chromosomes within nuclear three-dimensional space involves interactions between lamina (NL) lamina-associated domains (LAD). Contact individual LADs with NL are dependent upon H3K9me2 introduced G9a. mechanisms governing recruitment G9a distinct subcellular...