Mengran Wang

ORCID: 0000-0003-0165-4535
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About
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Research Areas
  • Microbial Natural Products and Biosynthesis
  • Photodynamic Therapy Research Studies
  • Nanoplatforms for cancer theranostics
  • Tuberculosis Research and Epidemiology
  • Bacterial Identification and Susceptibility Testing
  • Genomics and Phylogenetic Studies
  • Ocular Infections and Treatments
  • Abdominal vascular conditions and treatments
  • Plant and fungal interactions
  • Bacteriophages and microbial interactions
  • Heart Failure Treatment and Management
  • Diagnosis and treatment of tuberculosis
  • Vibrio bacteria research studies
  • Infectious Aortic and Vascular Conditions
  • Brain Tumor Detection and Classification
  • Phytase and its Applications
  • Enzyme Catalysis and Immobilization
  • Pneumothorax, Barotrauma, Emphysema
  • Plant Pathogens and Fungal Diseases
  • Amoebic Infections and Treatments
  • Actinomycetales infections and treatment
  • Mycobacterium research and diagnosis
  • Arctic and Antarctic ice dynamics
  • Pneumonia and Respiratory Infections
  • Remote Sensing and LiDAR Applications

Tianjin Normal University
2023-2024

Fudan University
2018-2023

Sun Yat-sen University
2018-2022

The First Affiliated Hospital, Sun Yat-sen University
2018-2022

Zhongshan Hospital
2018-2022

Beijing Friendship Hospital
2009-2021

Capital Medical University
2021

Metagenomic next-generation sequencing (mNGS) was suggested to potentially replace traditional microbiological methodology because of its comprehensiveness. However, clinical experience with application the test is relatively limited. From April 2017 December 2017, 511 specimens were collected, and their retrospective diagnoses classified into infectious disease (347 [67.9%]), noninfectious (119 [23.3%]), unknown cases (45 [8.8%]). The diagnostic performance pathogens compared between mNGS...

10.1093/cid/ciy693 article EN Clinical Infectious Diseases 2018-08-11

The emergence and spread of antibiotic resistance pose serious environmental health challenges. Attention has been drawn to phage therapy as an alternative approach combat with immense potential. However, one the obstacles is resistance, it can be acquired through genetic mutations, followed by consequences phenotypic variations. Therefore, understanding mechanisms underlying phage-host interactions will provide us greater detail on how optimize therapy. In this study, three lytic phages...

10.1128/spectrum.02072-22 article EN cc-by Microbiology Spectrum 2022-09-21

Abstract Background Aortoenteric fistula (AEF) is a rare cause of gastrointestinal bleeding and often misdiagnosed in clinical practice. Herein, case series AEFs are presented the characteristics, diagnosis, management strategies summarized. Methods A retrospective analysis was performed on consecutive hospitalized patients with final diagnosis AEF at Beijing Friendship Hospital, Capital Medical University, between January 1, 2007 March 31, 2020. The data including diagnostic procedures as...

10.1186/s12876-021-01629-4 article EN cc-by BMC Gastroenterology 2021-02-02

To evaluate the diagnostic accuracy of metagenomic next-generation sequencing (mNGS) for active tuberculosis (TB).We retrospectively collected 820 samples at Zhongshan Hospital, Fudan University in Shanghai, China, between 1 April 2017 and 31 March 2018. They were classified into TB cases (125, 15.2%) NOT (695, 84.8%) according to clinical diagnosis. Specimens evaluated by a regular microbiological assay mNGS performed parallel.Sixty-one confirmed 64 included. The overall sensitivity was...

10.21037/atm-20-2274 article EN Annals of Translational Medicine 2020-09-01

Abstract: A 50-year-old woman presented with right back pain, low fever, leukocytosis, a high level of C-reactive protein and erythrocyte sedimentation rate. Abdominal magnetic resonance imaging (MRI) revealed hypodense lesion in the suprarenal region, while PET/CT showed mildly increased metabolic activity. CT-guided percutaneous puncture was performed, foul-smelling thick pus removed, which indicated an anaerobic infection. smear both gram-positive gram-negative microorganisms. Traditional...

10.21037/atm.2020.01.123 article EN Annals of Translational Medicine 2020-03-01

As global climate change intensifies, the atmospheric circulation process is undergoing significant changes, and local water vapor pattern has also changed. This study takes Wei River Basin as research area. Firstly, an evaluation index system for extreme precipitation was established, time-series characteristics of magnitude, frequency, duration were analyzed. Statistical methods used to analyze non-consistency in changes indicators. Using spatial heterogeneity analysis methods, variation...

10.3390/w16020217 article EN Water 2024-01-08

Climate change has led to an increased frequency of extreme precipitation events, resulting in damage from rainstorms and floods. Rapid efficient flood forecasting is crucial. However, traditional hydrological simulation methods that rely on site distribution are limited by the availability data cannot provide fast accurate monitoring information. Therefore, this study took event Huoqiu County 2020 as example proposes a three-dimensional method based active passive satellites, which provides...

10.3390/rs15123015 article EN cc-by Remote Sensing 2023-06-09

abdominal tuberculosis (TB) is a common form of extrapulmonary TB but it still diagnostic dilemma in clinical practice. This study aimed to highlight the features and approaches for TB.seventy cases diagnosed were retrospectively collected between August 1st, 2015 June 30th, 2020. They classified as peritoneal TB, lymph node gastrointestinal visceral or mixed TB.eighteen patients with nine five two 36 TB. More than 65 % had other sites except abdomen. The median diagnosis time was 60 days....

10.17235/reed.2021.8022/2021 article EN publisher-specific-oa Revista Española de Enfermedades Digestivas 2021-01-01

White matter lesions (WMLs) are a common neuroimaging finding. With the aging of population and development imaging technology, detection rate WMLs in elderly increased gradually. closely associated with ischemic stroke. This article reviews pathophysiological mechanism, evaluation, clinical manifestation WMLs, its relationship stroke as well prevention treatment. Key words: Stroke; Brain Ischemia; White Matter; Magnetic Resonance Imaging

10.3760/cma.j.issn.1673-4165.2017.08.008 article EN Int J Cerebrovasc Dis 2017-08-28

Objective To assess the prognostic value of serum level and its change N-terminal pro-B-type natriuretic peptides (NT-proBNP) in elderly with acute decompensated heart failure preserved ejection fraction (HFpEF). Methods A total 138 consecutive patients (≥65 years old) admitted Geriatrics Gerontology Department at Beijing Friendship Hospital were enrolled from June 2013 to 2015.Demographic characteristics, combination diseases, medication administration, laboratorial echocardiographic...

10.3760/cma.j.issn.0254-9026.2018.01.002 article EN Zhonghua laonian yixue zazhi 2018-01-14
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