A5079212517- Birth, Development, and Health
- Clinical Nutrition and Gastroenterology
- Dietary Effects on Health
- Regulation of Appetite and Obesity
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pediatric Urology and Nephrology Studies
- Diabetes and associated disorders
- Infant Nutrition and Health
- Pediatric Hepatobiliary Diseases and Treatments
- COVID-19 Impact on Reproduction
- Pancreatic function and diabetes
- Neonatal Health and Biochemistry
- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Diabetes Management and Research
- Methemoglobinemia and Tumor Lysis Syndrome
- Pharmaceutical studies and practices
Cedars-Sinai Medical Center
2017-2021
Zero to Three
2015
University of California, Los Angeles
2012-2014
University of Southern California
2001
Children's Hospital of Los Angeles
2001
OBJECTIVE—To determine whether the continuous glucose monitoring system (CGMS) (MiniMed, Sylmar, CA) could be used to make clinical decisions and it has an impact on glycemia in pediatric type 1 diabetic subjects. RESEARCH DESIGN AND METHODS—Pediatric subjects were recruited if they had HbA1c >8.0% with management problems (n = 35) or episodes of severe nocturnal hypoglycemia unawareness associated ≤8.0% 12). A total 47 patients a mean value 8.6 ± 1.6% (mean age 11.8 4.6 years,...
Abstract Energy balance is regulated by circulating leptin concentrations and hypothalamic receptor (ObRb) signaling via STAT3 but inhibited SOCS3 PTP1B. Leptin enhances anorexigenic neuropeptides (POMC, MC3‐R, MC4‐R) activation while suppressing orexigenic (NPY, AgRP). We investigated in a sex‐specific manner the early (PN2) late (PN21) postnatal mechanisms response to intrauterine (IUGR), (PNGR), combined (IPGR) calorie growth restriction. At PN2, both male female IUGR were hypoleptinemic,...
Background: Premature infants depend on intravenous fat emulsions to supply essential fatty acids and calories. The dose of soybean‐based (S‐IFE) has been associated with parenteral nutrition (PN)–associated liver disease. This study's purpose was determine if low‐dose S‐IFE is a safe effective preventive strategy for cholestasis in preterm neonates. Materials Methods : multicenter randomized controlled trial gestational age (GA) ≤29 weeks. Patients <48 hours life were receive low (1...
Pre‐ and postnatal calorie restriction is associated with growth restriction, reduced circulating leptin concentrations, perturbed energy balance. Hypothalamic regulation of balance demonstrates enhanced orexigenic (NPY, AgRP) diminished anorexigenic (POMC, CART) neuropeptide expression (PN21), setting the stage for subsequent development obesity in female Sprague‐Dawley rats. Leptin replenishment during early period (PN2‐PN8) led to reversal hypothalamic orexigenic:anorexigenic ratio at...
The nursery notifies the medical team of a term female infant born at 40 weeks’ gestation via vacuum-assisted vaginal delivery. Maternal prenatal care was unremarkable. Prenatal laboratory findings are significant for maternal rubella nonimmune status and blood type B positive, antibody negative. Events surrounding delivery notable category II tracings on fetal monitor, 3+ meconium, 1 detachment (“pop-off”) during vacuum application. Apgar scores 9 5 minutes, respectively. At approximately...
Osmotic stress is a physical risk factor for adverse events related to peripheral parenteral nutrition (PN) administration, such as infiltration. We sought improve prediction of compounded PN osmolality utilizing basic nutrient solutions available North American neonatal intensive care units. This study tested the hypothesis that calculated osmolarity underestimates in PN.Osmolarity (mOsm/L) was commercial software. Osmolality (mOsm/kg) determined by freezing-point depression...