A5061010228- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Heart Failure Treatment and Management
- Renal Transplantation Outcomes and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Arrest and Resuscitation
- Organ Transplantation Techniques and Outcomes
- Obstructive Sleep Apnea Research
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Neuroscience of respiration and sleep
- Heart Rate Variability and Autonomic Control
- Fuel Cells and Related Materials
- Heart rate and cardiovascular health
- Pulmonary Hypertension Research and Treatments
- Organ and Tissue Transplantation Research
- Diabetes Treatment and Management
- Pancreatic function and diabetes
- Congenital Heart Disease Studies
- COVID-19 Clinical Research Studies
- Sleep and Wakefulness Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Long-Term Effects of COVID-19
The Ohio State University Wexner Medical Center
2015-2025
The Ohio State University
2014-2024
Health Net
2024
Christ Hospital
2024
University of California, Riverside
2024
Allegheny General Hospital
2017
Virginia Commonwealth University
2017
University of Chicago
2017
Abbott (United States)
2017
Columbia University
2017
Isolated diastolic dysfunction is found in almost half of asymptomatic patients with well-controlled diabetes and may precede heart failure. However, mechanisms that underlie during are not well understood. We tested the hypothesis isolated associated impaired myocardial Ca(2+) handling type 1 diabetes. Streptozotocin-induced diabetic rats were compared age-matched placebo-treated rats. Global left ventricular performance systolic function preserved animals. Diabetes-induced was evident on...
Gastrointestinal (GI) bleeding is one of the most common complications after continuous-flow left ventricular assist device implantation. More than third patients with incident bleed go on to develop recurrent GI bleeding. Octreotide, a somatostatin analog, proposed reduce risk in this population.This multicenter, retrospective analysis evaluated 51 who received secondary prophylaxis octreotide their index from 2009 2015. All had hospitalization for and discharge. Patient demographics,...
Heart rate (HR) affects heart failure outcomes, via uncertain mechanisms that may include left ventricular remodeling. However, in human myocardium, HR change has not been associated with a particular remodeling molecular phenotype. Patients nonischemic dilated cardiomyopathy (N=22) sinus rhythm and refractory to β-blockade for both lowering reverse were randomized 2:1 double-blind the HCN4 (hyperpolarization-activated cyclic nucleotide-gated potassium channel 4) inhibitor ivabradine or...
Although percutaneous, adenoviral-mediated intracoronary gene delivery to the heart has been demonstrated in some species, consistent and safe methodology is needed before clinical applicability possible. In this study, we examine effects of altering flow rate obtaining an adequate seal between catheter coronary lumen on successful cardiac myocardial injury both piglets adult rabbits. To study efficacy vivo transfer, utilized adenoviral vectors containing either β2-adrenergic receptor or...
To test the hypotheses that receipt of Medicaid or Medicare (versus private insurance self-pay) and low socioeconomic status (SES) leads to increased mortality lower chances transplantation among heart transplant (HTx) candidates with bridge left ventricular assist devices (BTT LVADs).Survival while awaiting HTx has improved use BTT LVADs. However, it is unknown whether benefits extend uniformly across patient groups based on status.Data from United Network Organ Sharing (UNOS) registry...