A5055302405- Thyroid Cancer Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Sesquiterpenes and Asteraceae Studies
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Asthma and respiratory diseases
- Phytochemicals and Antioxidant Activities
- Sirtuins and Resveratrol in Medicine
- Essential Oils and Antimicrobial Activity
- Plant Toxicity and Pharmacological Properties
- Chemical Synthesis and Analysis
- Genomics, phytochemicals, and oxidative stress
- Antioxidant Activity and Oxidative Stress
- Cancer-related Molecular Pathways
- Circular RNAs in diseases
- Prostate Cancer Treatment and Research
- Coenzyme Q10 studies and effects
- Phosphodiesterase function and regulation
- Marine Sponges and Natural Products
- Estrogen and related hormone effects
- Nanoparticle-Based Drug Delivery
- RNA modifications and cancer
- Reproductive System and Pregnancy
- RNA Research and Splicing
- Phytochemical and Pharmacological Studies
Shahid Beheshti University of Medical Sciences
2017-2025
University of Gonabad
2022
Payame Noor University
2021
GTx (United States)
2020
Shiraz University of Medical Sciences
2014-2019
Oxidative stress is a major complication in diabetes mellitus. The aim of this study was to investigate potential antioxidant activity coenzyme Q10 (Co Q10) against hyperglycemia-induced oxidative diabetic rat and unraveling its mechanism action by focusing on silent information regulator 1 (Sirt1) nuclear factor E2-related 2 (Nrf2) mRNA expression level. Furthermore, the two Nrf2-dependent enzymes (superoxide dismutase catalase) liver rats studied. After induction using streptozotocin (55...
Breast cancer is the main reason for cancer-related death in women. Britannin a sesquiterpene lactone compound derived from
Cancer metastasis remains the most challenging issue in cancer therapy. Recent reports show that accounts for over 90% of cancer-associated deaths world. Metastasis is a multi-step process by which cells spread to distant tissues and organs beyond primary site. The metastatic propagation different cancers under surveillance several regulating processes factors related cellular signaling pathways. Plant-derived phytochemicals are bioactive components plants with variety biological medicinal...
Neurotransmitters and neurotrophic factors are signaling molecules that play a crucial role in cell proliferation, differentiation, survival functions of neurons. It is believed caloric restriction could help the health nervous system by affecting synthesis neurotrophins neurotransmitter oxygen radical metabolism. The objective was to investigate plasma levels serotonin, dopamine, brain-derived factor (BDNF), nerve growth (NGF) 29 healthy fasted subjects (22 women 7 men) during month fasting...
Formation of atherosclerotic plaques is the major cause coronary artery disease (CAD). Several lines study have revealed role oxidative stress in CAD pathogenesis. In present aim was to investigate and antioxidative markers patients a control population. The sample comprised acute syndrome (ACS) patients, chronic healthy controls (n=30/group). Blood samples subjects were collected measure concentrations reduced glutathione (GSH), malondialdehyde (MDA) percentage MDA release as well activity...
Uttarakhand Himalayan region holds Asteraceae or Compositae as the largest family of flowering, medicinal and aromatic plants. Species belonging to this rises from low altitude alpine region. Among Asteraceae, Saussurea obvallata (DC.) Edgew. is widely used in several indigenous systems medicine. Flowers, leaves rhizomes S. are for traditional, religious, therapeutic ornamental purposes. Aim study was determine chemical composition antibacterial efficacy petroleum ether extract (PEE)...
Propranolol, a beta-adrenergic blocker, is used in the treatment of large number cardiovascular diseases such as hypertension and arrhythmias. combination with furosemide, to treat hypertensive disorders although their side effect profile not very obvious. In present study, effects drugs furosemide propranolol were corporately investigated both on glutathione homeostasis antioxidant ACHN cells.The cytoxicities these two clinically important human kidney cell lines evaluated using MTT...
Rutin has been reported as a potential anti-cancer agent for several decades. This study evaluated the effects of rutin on proliferation, metastasis, and angiogenesis MDA-MB-231 MCF-7 breast cancer cell lines. Increasing concentrations significantly stimulated proliferation cells compared to controls. Wound scratch assay demonstrated that had an inducing effect migration cells. In cells, upregulated MKI67, VIM, CDH2, FN1, VEGFA downregulated CDH1 THBS1 genes. It also increased N-cadherin...