A5101884053- Geological and Geochemical Analysis
- Geochemistry and Geologic Mapping
- Phytochemicals and Antioxidant Activities
- Geochemistry and Geochronology of Asian Mineral Deposits
- earthquake and tectonic studies
- High-pressure geophysics and materials
- Natural product bioactivities and synthesis
- Geological and Geophysical Studies
- Medicinal Plants and Bioactive Compounds
- Geoscience and Mining Technology
- Essential Oils and Antimicrobial Activity
- Probiotics and Fermented Foods
- Pharmacological Effects of Natural Compounds
- Natural Antidiabetic Agents Studies
- Tea Polyphenols and Effects
- Gut microbiota and health
- Phytochemical and Pharmacological Studies
- Agriculture and Biological Studies
- Ruminant Nutrition and Digestive Physiology
- Food composition and properties
- Proteins in Food Systems
- Hydrocarbon exploration and reservoir analysis
- Animal health and immunology
- Biological Stains and Phytochemicals
- Sirtuins and Resveratrol in Medicine
Beijing Normal University - Hong Kong Baptist University United International College
2022-2025
Hong Kong Baptist University
2022-2025
State Key Laboratory of Continental Dynamics
2007-2024
Northwest University
1997-2024
Beijing Normal University
2023
Chinese Academy of Agricultural Mechanization Sciences
2022
South China Agricultural University
2020
University of Newcastle Australia
2007-2016
Continental (United Kingdom)
2011
Yanbian University of Science and Technology
2007
Abstract This review highlights the increasing interest in one of natural compounds called saponins, for their potential therapeutic applications addressing inflammation which is a key factor various chronic diseases. It delves into molecular mechanisms responsible anti‐inflammatory effects these amphiphilic compounds, prevalent plant‐based foods and marine organisms. Their structures vary with soap‐like properties influencing historical uses traditional medicine sparking renewed scientific...
Edible flower of Hemerocallis citrina Baroni (H. citrina), commonly known as "Huang Huacai" in China, is a medicinal and edible vegetable with high nutritional value. Two major kinds secondary metabolites identified H. are flavonoids phenolic acids. have been found to possess beneficial effects including anti-inflammatory, antioxidant, anticancer, antidepressant, antimicrobial, anti-constipation, anti-aging, sleep-improving, lactation-promoting effects. These health benefits carried through...
Abstract In contrast to its widespread traditional and popular culinary use reduce weight, Vigna angularis (adzuki beans) was not subjected sufficient scientific scrutiny. Particularly, saponins whose role never investigated before unveil the beans’ antidiabetic anti‐obesity effects. Four vital pancreatic intestinal carbohydrate enzymes were selected assess potency of triterpenoidal V. bind activate these proteins through high‐precision molecular modeling dynamics mechanisms with accurate...
Alzheimer’s disease (AD), one of the neurodegenerative disorders, afflicts negatively across whole world. Due to its complex etiology, no available treatments are disease-altering. This study aimed explore isolated saponins profiles from Platycodon grandiflorum in binding pockets six target proteins AD using computational and quantum chemistry simulations. Initially, saponin compounds were docked enzymes, such as GSK-3β synapsin I, II, III. The subsequent research MD simulations best three...
In this study, network pharmacology, bioinformatics and molecular docking were used to explore the active phytochemicals, hub genes, potential mechanisms of Gleditsiae Spina in treating colorectal cancer..The targets Spina, related CRC derived from databases. We identified genes for anti-colorectal cancer following protein-protein-interaction (PPI) network. Furthermore, Gene Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) enrichment analyze a macro perspective. Finally, we verified by...
The global prevalence of obesity is a pressing health issue, increasing the medical burden and posing significant risks to humans. side effects complications associated with conventional medication surgery have spurred search for anti-obesity drugs from plant resources. Previous studies suggested that Artemisiae argyi Folium (Aiye) water extracts could inhibit pancreatic lipase activities, control body weight increase, improve plasma lipids profile. However, exact components mechanisms were...
This study aims to identify the mechanism of geniposide regulating oxidative stress in colorectal cancer (CRC) through network pharmacology and bioinformatics analysis. Targets geniposide, stress-related targets related CRC were applied from databases. The hub genes for identified with protein–protein interaction (PPI) network. Furthermore, we Gene ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) enrichment analyze a macro perspective. We verified by molecular docking, GEPIA, HPA...
Obesity has emerged as a significant health concern, it is disease linked to metabolic disorders in the body and characterized by excessive accumulation of lipids. As plant-derived food, Platycodon grandiflorum (PG) was reported many studies, indicating that saponins from PG can improve obesity effectively. However, anti-obesity its mechanisms have not been fully identified. This study identified active their molecular targets for treating obesity. The TCMSP database used obtain information...