A5102787259- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Parathyroid Disorders and Treatments
- Gastroesophageal reflux and treatments
- Genetic Syndromes and Imprinting
- Medical Imaging and Pathology Studies
- Oral and Maxillofacial Pathology
- Transplantation: Methods and Outcomes
- Liver Disease and Transplantation
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Eosinophilic Esophagitis
- Renal Transplantation Outcomes and Treatments
- Pediatric health and respiratory diseases
- Vitamin D Research Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis C virus research
- IL-33, ST2, and ILC Pathways
- Gastrointestinal motility and disorders
- Bone health and osteoporosis research
- Inflammasome and immune disorders
- Adenosine and Purinergic Signaling
Affiliated Hospital of Qingdao University
2021-2025
Peking Union Medical College Hospital
2014-2025
Qingdao University
2021-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2025
Renji Hospital
2024
Shanghai Jiao Tong University
2024
Changsha Medical University
2023-2024
University of Southern California
2022-2023
National Health and Family Planning Commission
2022
Chinese Academy of Sciences
2022
Background Previous observational studies have investigated the association between endocrine and metabolic factors idiopathic pulmonary fibrosis (IPF), yet produced inconsistent results. Therefore, it is imperative to employ Mendelian randomization (MR) analysis method conduct a more comprehensive investigation into impact of on IPF. Methods The instrumental variables (IVs) for 53 were sourced from publicly accessible genome-wide study (GWAS) databases, with GWAS summary statistics...
Background The existing literature on the relationship of hyperparathyroidism with both blood counts and biochemical indicators primarily comprises observational studies, which have produced inconsistent findings. This study aimed to evaluate causal between indicators. Methods Mendelian randomization (MR) analyses were conducted investigate associations identified 55 genome-wide association (GWAS) for data was obtained from FinnGen, while GWASs sourced UK Biobank (UKBB). Results MR analysis...
The actions of enteric 5-HT are terminated by transporter (SERT)-mediated uptake, and gastrointestinal motility is abnormal in SERT −/− mice. We tested the hypothesis that adaptive changes 3 receptors help mice survive despite inefficient inactivation. Expression mRNA encoding 3A subunits was similar +/+ mice, but 3B fourfold less found, situ hybridization, epithelial cells neurons. evoked a fast inward current myenteric neurons pharmacologically identified as mediated. EC 50 response lower...
Ye X, Kuo H-T, Sampaio MS, Jiang Y, Bunnapradist S. Risk factors for development of new-onset diabetes mellitus after transplant in adult lung recipients. Clin Transplant 2011: 25: 885–891. © 2010 John Wiley & Sons A/S. Abstract: The objectives this study are to examine the incidence (NODAT) and identify its risk recipients using Organ Procurement Network/United Network Sharing database. Between July 2004 December 2007, a total 3540 adults (≥18 yr old) received their first single- or...
The objectives of this study are to examine the incidence new-onset diabetes mellitus (NODM) and identify its risk factors in adult heart recipients using Organ Procurement Transplant Network/United Network Sharing database.Between July 2004 December 2007, 4972 adults (aged 18 years or older) received their first transplant alone, had at least one follow-up report posttransplant diabetic status. Among these, 3763 were identified as not having pretransplant. Risk for NODM examined...
Sinonasal inverted papilloma (SNIP) has a risk of malignant transformation into SNIP with squamous cell carcinoma (SNIP-SCC). Early detection SNIP-SCC is crucial for patient outcomes. This study aimed to evaluate the utility tumor-related hematological indices in early diagnosis and develop nomogram incorporating imaging clinical features. included 159 patients (n = 34) or without 125) SCC. Univariate multivariate logistic regression analyses were employed identify independent factors...
To the Editor, Chronic rhinosinusitis (CRS) is a common otorhinolaryngological disease with high global incidence and significant impact on patient's quality of life. It often divided into chronic without nasal polyps (CRSsNP) (CRSwNP) according to phenotype, together division eosinophilic CRS (eCRS) noneosinophilic (non-eCRS) endotype [1]. Associations between ABO blood groups various diseases have been reported [2]. However, little known relationship CRS. Therefore, objective this study...
To evaluate the diagnostic accuracy of some noninvasive fibrosis models in Chinese patients with nonalcoholic fatty liver disease (NAFLD).Consecutive biopsy-proven NAFLD were recruited from a single center January 2005 to December 2010. Advanced (stage 3 and 4) was defined using Kleiner criteria. The area under receiver operating characteristic curve (AUROC) used compare score (NFS), FIB-4 index, aspartate transaminase (AST)/platelet ratio index (APRI), AST/alanine (ALT) (AAR) body mass...
Background Sinonasal malignant tumors (SNMTs) have a high recurrence risk, which is responsible for the poor prognosis of patients. Assessing risk in SNMT patients current problem. Purpose To establish an MRI‐based radiomics nomogram assessing relapse with SNMT. Study Type Retrospective. Population A total 143 68.5% females (development/validation set, 98/45 patients). Field Strength/Sequence 1.5‐T and 3‐T, fat‐suppressed fast spin echo (FSE) T2‐weighted imaging (FS‐T2WI), FSE T1‐weighted...
Advanced fibrosis or cirrhosis is still regarded as a contraindication for kidney transplantation alone by most centers. The value of aminotransferase to platelet ratio index (APRI) and other non-invasive markers has been less studied in hepatitis C virus (HCV)-positive patients with concurrent end-stage renal disease predict hepatic fibrosis. Can these be used effectively decrease the number biopsies done being evaluated transplantation?Our study population included 255 liver biopsy data....
Human endogenous retrovirus-H long terminal repeat-associating protein 2 is a newly identified immune checkpoint molecule that was aberrantly expressed in many malignant tumors. However, its expression medullary thyroid carcinoma still unclear. This study aimed to investigate the human tissues and evaluate relationships between clinicopathologic together with prognostic relevance.Using 51 surgical specimens obtained from patients, levels of tumor adjacent noncancerous were measured by...
Objectives: Sinonasal inverted papilloma (SNIP) is one of the most common benign tumors nasal cavity and sinuses at risk for recurrence malignant transformation. It crucial to precisely predict SNIP before surgery determine optimal surgical technique prevent recurrence. This study aimed evaluate diagnostic value computed tomography (CT) features clinical characteristics develop validate a clinically effective nomogram. Methods: Here, 267 patients with 273 unilateral chronic rhinosinusitis...
The aim was to investigate the short-term impact of time restricted feeding on patients with suspected gastroesophageal reflux disease (GERD).Lifestyle modifications are often suggested, but role diet in GERD is unclear. Intermittent fasting popular media and has demonstrated potential benefits weight loss inflammatory conditions as well alterations gastrointestinal hormones.Patients who were referred for 96-hour ambulatory wireless pH monitoring off proton pump inhibitor symptoms screened...
Summary Aim: The liver is an important reference organ for positron emission tomography/ computed tomography (PET-CT) examination using 18F-fluorodeoxyglucose (18F-FDG). However, 18F-FDG uptake by the affected many factors. We therefore investigated effect of hepatic function on in liver. Methods: A retrospective analysis data and mean standardized up-take value (SUV) during PET-CT 500 (381 males, 119 females, aged 27–71) physical examinees. Results: SUV was 1.88 ± 0.20. correlation...
<b><i>Introduction:</i></b> Chronic rhinosinusitis with nasal polyps (CRSwNP) is an immunologic disease, and pyroptosis, inflammation-based cellular death, strictly modulates CRSwNP pathology, whereas the pyroptosis genes mechanisms involved in remain unclear. Herein, we explored disease biomarkers potential therapeutic targets for immune regulation using bioinformatics analysis tissue-based verification. <b><i>Methods:</i></b> We retrieved...
Respiratory epithelial adenomatoid hamartoma (REAH) is a benign lesion commonly occurring in the nasal cavity and sinuses. It often accompanied by polyps (NP). While histological features of these two conditions have been studied, there limited knowledge about their differences underlying immunopathology.