Guojue Wang

ORCID: 0000-0003-0187-1126
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About
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Research Areas
  • Seismic Performance and Analysis
  • Structural Behavior of Reinforced Concrete
  • Structural Load-Bearing Analysis
  • Structural Health Monitoring Techniques
  • Structural Engineering and Vibration Analysis
  • Masonry and Concrete Structural Analysis
  • Rheumatoid Arthritis Research and Therapies
  • Bone health and treatments
  • T-cell and B-cell Immunology
  • Bone Metabolism and Diseases
  • Chemokine receptors and signaling
  • Fire effects on concrete materials
  • Vibration and Dynamic Analysis
  • Cancer-related gene regulation
  • Innovative concrete reinforcement materials
  • Osteomyelitis and Bone Disorders Research
  • Systemic Lupus Erythematosus Research
  • Geotechnical Engineering and Underground Structures
  • Monoclonal and Polyclonal Antibodies Research
  • Epigenetics and DNA Methylation
  • NF-κB Signaling Pathways
  • Cytokine Signaling Pathways and Interactions
  • Advanced Computational Techniques and Applications

China Coal Technology and Engineering Group Corp (China)
2023-2025

Chongqing University
2011-2023

Chongqing University of Science and Technology
2023

Shanghai Jiao Tong University
2016-2023

Rationale: Protein arginine methyltransferase 5 (PRMT5) is an oncogene that promotes tumor cell proliferation, invasion and metastasis. However, the underlying mechanisms by which PRMT5 contributes to progression of cervical cancer especially microenvironment remain poorly understood. Methods: expression level was analyzed Q-PCR, western blot, immunohistochemistry, TCGA database. The role in growth observed transplanted models, function T cells vitro co-culture system investigated through...

10.7150/thno.59605 article EN cc-by Theranostics 2021-01-01

Abstract In order to study the factors that affect crack width, cracking mechanism, and development laws of U‐shaped steel concrete composite (USCC) beam, propose a width calculation formula suitable for this new type tests were conducted on four simply supported beam specimens. These specimens, which featured different forms, shear connectors, longitudinal reinforcement arrangements, all subjected negative bending moments. Research has shown USCC beams H‐shaped (HSCC) exhibited basically...

10.1002/suco.202400463 article EN Structural Concrete 2025-01-05

Summary Paeoniflorin (PF), extracted from the root of Paeonia lactiflora Pall, exhibits anti‐inflammatory properties in several autoimmune diseases. Osteoclast, only somatic cell with bone resorbing capacity, was direct cause destruction rheumatoid arthritis (RA) and its mouse model, collagen‐induced (CIA). The objective this study to estimate effect PF on CIA mice, explore mechanism destruction. We demonstrated that treatment significantly ameliorated through inflammatory response...

10.1111/imm.12907 article EN Immunology 2018-02-17

In this study, the ratio of lateral stiffness stilted story to that second was proposed as (SSR) quantify vertical irregularities hillside buildings. A quasi-static experiment conducted on a plane frame with an SSR 40 in slope direction. Experimental results were compared those 1.01. The show is important factor influencing seismic failure modes As decreases, structural ductility and deformation capacity improve, degradation decelerates.

10.1080/13632469.2023.2287136 article EN Journal of Earthquake Engineering 2023-11-27

Abstract The IL‐7/IL‐7R pathway plays a vital role in the immune system, especially inflammatory response. Monocytes/macrophages (osteoclast precursors) have been recently recognized as important participants osteoclastogenesis of rheumatoid arthritis (RA) patients. Here, we aimed to investigate therapeutic potential RA and determine whether it could restrain osteoclastogenic functions therefore ameliorate RA. Firstly, collagen‐induced (CIA) mice were administered with IL‐7Rα‐target...

10.1111/imm.13351 article EN Immunology 2021-05-02

Rheumatoid arthritis (RA) is a complex systemic autoimmune disorder that primarily involves joints, further affects the life quality of patients, and has increased mortality. The pathogenesis RA multiple pathways, resulting in some patients showing resistance to existing drugs. Salubrinal small molecule compound recently been shown exert beneficial effects on bone tissue. However, effect not clearly confirmed. Hence, we induced collagen-induced (CIA) DBA/1J mice found treatment decreased...

10.3390/ijms22073501 article EN International Journal of Molecular Sciences 2021-03-28

Extensive investigations for the inspect and record of Building Energy Conservation (BEC)have been in four representative cities thermal efficiency sub areas China, existing problems current BEC China are analyzed. Based on actual situation inspect, solution is proposed. model mentioned above, Information Management System item suiting each features, which consists system login management module, construction-related units entries construction project information developed. This owns good...

10.1109/cdciem.2011.432 article EN International Conference on Computer Distributed Control and Intelligent Environmental Monitoring 2011-02-01
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