Ionel Nati

ORCID: 0000-0003-0187-3682
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Research Areas
  • Endometriosis Research and Treatment
  • Uterine Myomas and Treatments
  • Endometrial and Cervical Cancer Treatments
  • Anorectal Disease Treatments and Outcomes
  • Reconstructive Surgery and Microvascular Techniques
  • Tumors and Oncological Cases
  • Teratomas and Epidermoid Cysts
  • Surgical site infection prevention
  • Intraperitoneal and Appendiceal Malignancies
  • Ovarian cancer diagnosis and treatment
  • Head and Neck Surgical Oncology
  • Regulation of Appetite and Obesity
  • Hernia repair and management
  • Adipose Tissue and Metabolism
  • Pelvic floor disorders treatments
  • Prenatal Screening and Diagnostics
  • Neurofibromatosis and Schwannoma Cases
  • Bariatric Surgery and Outcomes
  • Pregnancy and preeclampsia studies
  • Dermatological and COVID-19 studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • Blood disorders and treatments
  • Platelet Disorders and Treatments
  • Sarcoma Diagnosis and Treatment
  • Gestational Diabetes Research and Management

Iuliu Hațieganu University of Medicine and Pharmacy
2023-2025

Institute of Oncology Prof. Dr. Ion Chiricuta
2023

Background and Clinical Significance: Retrorectal cystic hamartomas (“Tailgut cysts”) are rare developmental cysts that appear in the retrorectal space, arising from aberrant remnants of post-anal primitive gut case an incomplete embryogenetic involution. Case Presentation: We present a 30-year-old woman with history chronic lower abdominal pain. Other digestive symptoms, like rectal fullness, constipation, pain on defecation, bleeding or genitourinary obstruction were not associated. During...

10.3390/diagnostics15010108 article EN cc-by Diagnostics 2025-01-04

Abdominal cystic masses are diagnosed during the intrauterine period and have a relatively low incidence. Fetal ovarian cysts most common form prenatally or immediately after birth. The pathophysiology of development these types tumors is not fully elucidated, with hyperstimulation caused by maternal placental hormones being accepted hypothesis. During development, diagnosis fetal often made accidentally usual check-up ultrasounds corresponding to first, second, third trimesters pregnancy....

10.3390/medicina59020186 article EN cc-by Medicina 2023-01-17

Endometriosis is known to be a chronic, debilitating disease. The pathophysiological mechanisms of endometriosis development include local chronic inflammation and certain degree immune deficit. We investigated the relationship between severity, IL-8, IL-10, BDNF, VEGF-A serum tissue levels, patient-related pain, physical activity in cohort 46 patients diagnosed with who underwent surgery. same panel biomarkers was control group 44 reproductive-aged non-endometriotic gynecological pathology...

10.20944/preprints202406.2067.v1 preprint EN 2024-06-29

Due to the still large number of patients diagnosed with pelvic neoplasms (colorectal, gynecological, and urological) in advanced stages right from initial diagnosis, surgery represents mainstay treatment, often implying wide, eventually multi-organ resections order achieve negative surgical margins. Perineal wound morbidity, particularly extralevator abominoperineal excision, leads complications local infection rates up 40%. Strategies reduce postoperative are being pursued address this...

10.3390/jpm13121711 article EN Journal of Personalized Medicine 2023-12-14

Endometriosis is known to be a chronic, debilitating disease. The pathophysiological mechanisms of endometriosis development include local chronic inflammation and certain degree immune deficit. We investigated the relationship between severity, IL-8, IL-10, BDNF, VEGF-A serum tissue levels, patient-related pain, physical activity in cohort 46 patients diagnosed with who underwent surgery. same panel biomarkers was control group 44 reproductive-aged non-endometriotic gynecological pathology...

10.3390/diagnostics14161822 article EN cc-by Diagnostics 2024-08-21

Due to the still large number of patients diagnosed with pelvic neoplasms (colorectal, gynecological, and urological) in advanced stages right from initial diagnosis, surgery represents mainstay treatment, often implying wide, eventually multi-organ resections order achieve negative surgical margins. Perineal wound morbidity, particularly extralevator abominoperineal excision, leads complications local infection rates up 40%. Strategies reduce postoperative are pursued address this issue.The...

10.20944/preprints202311.1995.v1 preprint EN 2023-12-01

Due to the still large number of patients diagnosed with pelvic neoplasms (colorectal, gynecological, and urological) in advanced stages right from initial diagnosis, surgery represents mainstay treatment, often implying wide, eventually multi-organ resections order achieve negative surgical margins. Perineal wound morbidity, particularly extralevator abominoperineal excision, leads complications local infection rates up 40%. Strategies reduce postoperative are pursued address this issue.The...

10.20944/preprints202311.1995.v2 preprint EN 2023-12-01

Endometriosis is a common gynecological condition with complex physio-pathological background. This study aimed to assess the role of Rubus idaeus leaf extract (RiDE) as potential therapeutic agent in reducing size endometriotic lesions and modulate plasma expression MMP-2, MMP-9, TGF-β1. The were induced rat model by autologous transplant endometrium. Thirty-six female rats, Wistar breed, endometriosis, divided into four groups underwent treatment for 28 days. CTRL group received 0.5 mL/day...

10.3390/molecules29040778 article EN cc-by Molecules 2024-02-08

Obesity, characterized by an excess of adipose tissue, has become a significant global health issue. The prevalence obesity increased markedly in recent decades worldwide, with sharp rise also observed developing countries, particularly urban areas. Addressing during pregnancy is crucial for several reasons and presents challenges specialists obstetrics gynecology. Objectives: aim the present study was to investigate correlation between its implications childbirth. Materials Methods: We...

10.3390/jpm14070683 article EN Journal of Personalized Medicine 2024-06-26

Background/Objectives: The rapidly increasing rate of obesity has become an extremely important public health problem, particularly in developed countries. Obesity is associated with a range problems, often referred to as the metabolic syndrome. Adipose tissue now regarded endocrine organ responsible for hormonal secretion adipokines, which are cytokines involved various physiological processes. It been established that adipokines play key role regulation many processes human body. aim...

10.3390/nu16234022 article EN Nutrients 2024-11-24

Retrorectal cystic hamartomas (“Tailgut cysts”) are rare developmental cysts that appear in the retrorectal space, arising from aberrant remnants of post-anal primitive gut case an incomplete embryogenetic involution. We present a 30-year-old woman with history chronic lower abdominal pain. Other digestive symptoms, like rectal fullness, constipation, pain on defecation, bleeding or genitourinary obstruction symptoms were not associated. During period 3 years she had undergone several...

10.20944/preprints202412.0402.v1 preprint EN 2024-12-04

Endometriosis, a chronic hormone-dependent condition affecting 10% of women globally, impacts pelvic organs and occasionally distant sites, causing pain, infertility, sexual dysfunction. Biomarkers such as IL-8, IL-10, BDNF influence inflammation, nerve sensitization, pain. This study investigates their relationship with quality life, focusing on dyspareunia related dysfunctions, assessed using the Female Sexual Function Index (FSFI). Dyspareunia, prominent symptom endometriosis, is linked...

10.3390/ijms26010162 article EN International Journal of Molecular Sciences 2024-12-27
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