- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Ultrasound in Clinical Applications
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Cardiovascular and Diving-Related Complications
- Trauma Management and Diagnosis
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Congenital Heart Disease Studies
- Hemodynamic Monitoring and Therapy
- Renal function and acid-base balance
- Anesthesia and Sedative Agents
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Aortic Disease and Treatment Approaches
- Electrical and Bioimpedance Tomography
- Transplantation: Methods and Outcomes
- Potassium and Related Disorders
- Heterotopic Ossification and Related Conditions
- Cardiac and Coronary Surgery Techniques
- Renal and related cancers
- Advanced Sensor Technologies Research
University of Washington Medical Center
2017-2025
University of Washington
2016-2024
University of Ottawa
2021
Seattle Children's Hospital
2020
Tufts University
2014
Duke Medical Center
2009
Bone morphogenetic proteins (BMPs) signal through the BMP type I and II receptors to regulate cellular processes, including embryonic development. The activin-like kinase (ALK)3 ALK6 share a high degree of homology, yet possess distinct signaling roles. Here, we report that although transforming growth factor (TGF)-beta III receptor (TbetaRIII) enhanced both ALK3 signaling, TbetaRIII more potently ALK6-mediated stimulation BMP-responsive promoters XVent2 3GC2, up-regulation early response...
•Degenerative common AVC defect can mimic rheumatic MV stenosis.•Closure of primum ASD be achieved percutaneously.•Live 3D multiplanar TEE is crucial for procedural guidance.
We present our initial experience with the fourth-generation MitraClip™ (G4) system and propose preliminary criteria for device selection.The G4 recently underwent a "controlled release" transcatheter edge-to-edge mitral valve repair. The four new devices include technical improvements such as controlled gripper actuation (independent leaflet capture) continuous left atrial pressure monitoring. To date, patient-specific selection algorithm, technology's impact on procedural times success,...
We present a patient who developed acute intraoperative cardiac failure requiring open message immediately after uncomplicated heart transplantation. After successful resuscitation and establishment of extracorporeal membrane oxygenation, coronary angiography showed diffuse multivessel vasospasm, which responded to intracoronary IV administration vasodilators. Cardiac function gradually improved the was discharged home prolonged hospital course. allograft dysfunction associated with...
BACKGROUND: Mitral annular calcification with valve dysfunction remains a challenging syndrome. Operative risk is high, and available transcatheter therapies are limited. METHODS: This study describes our initial experience novel procedure to address large mitral annuli when no surgical or trial-based replacement device available. The rationale was shorten the intercommissural distance using commissural edge-to-edge repair (TEER) followed by valve-in-mitral balloon-expandable aortic...
•Severe complications from TEE imaging are uncommon.•Airway compression occurs in children and as rare case reports adults.•This can be caused by an anteflexed probe adult with tracheobronchomalacia.
McFaul, Colleen M. MD, FRCPC; Hill, Bryce MD,; Sheu, Richard FASE Author Information