Mortality in coronavirus disease of 2019 (COVID-19) is associated with increases prothrombotic parameters, particularly D-dimer levels. Anticoagulation has been proposed as therapy to decrease mortality, often adjusted for illness severity. We wanted investigate whether anticoagulation improves survival COVID-19 and if this improvement This a cohort study simulating an intention-to-treat clinical trial, by analyzing the effect on mortality chosen first 48 hours hospitalization. analyzed...

This cohort study assesses the prevalence of lupus anticoagulant (LA) positivity in patients with coronavirus disease 2019 (COVID-19) and examines association LA patient outcomes.

Background During a pandemic, it is important for clinicians to stratify patients and decide who receives limited medical resources. Machine learning models have been proposed accurately predict COVID-19 disease severity. Previous studies typically tested only one machine algorithm performance evaluation area under the curve analysis. To obtain best results possible, may be test different algorithms find prediction model. Objective In this study, we aimed use automated (autoML) train various...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cycle threshold (Ct) has been suggested as an approximate measure of initial viral burden. The utility threshold, at admission, a predictor disease severity not thoroughly investigated.We conducted retrospective study SARS-CoV-2 positive, hospitalized patients from 3/26/2020 to 8/5/2020 who had Ct data within 48 hours admission (n = 1044). Only with complete survival data, discharged 774) or died in hospital 270), were included our...

Study Design. This study investigated the use of mechanically elicited electromyograms during placement pedicle screws in 89 patients undergoing surgery for spinal stenosis. Summary Background Data. Several methods monitoring nerve roots are available. However, may be more sensitive to mechanical irritation by than other methods. Methods. Mechanically were recorded muscle groups innervated cervical or lumbar roots. Confirmation surgical activity with level electromyogram was correlated....

BACKGROUND When manufacturing chimeric antigen receptor (CAR) T cells using anti‐CD3/anti‐CD28 beads, ex vivo T‐cell expansion is dependent on the composition of leukocytes used in process. We investigated effects leukocyte CAR and characteristics an alternative method. METHODS Anti–B‐cell maturation CD19‐CAR were manufactured autologous peripheral blood mononuclear cell (PBMNC) concentrates. The PBMNCs enriched for lymphocytes density gradient separation, which culture initiation. was...

Study Design This study determined the relative efficacy of somatosensory-evoked potentials and motor-evoked in monitoring spinal cord function during surgery for patients with idiopathic versus neuromuscular scoliosis. Objectives To determine whether scoliosis demonstrate significantly different recorded surgery. Summary Background Data Ashkenaze et al (1993) others have reported that cortical are unreliable when used to monitor It was recommended other neurophysiologic tests be used....

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has a variable clinical course with significant mortality. Early reports suggested higher rates of SARS‐CoV‐2 infection in patients type A blood and enrichment individuals among COVID‐19 mortalities. Study Design Methods The study includes all hospitalized or an emergency department (ED) visit who were tested for between March 10, 2020 June 8, had positive test result by nucleic acid (NAT) performed on...

The novel coronavirus severe acute respiratory syndrome 2 (SARS-CoV2) is the causative agent of disease 2019 (COVID-19). presenting symptoms this virus are variable, and there an increasing body literature on risk factors for mortality. aim study was to evaluate effect initial aspartate aminotransferase (AST) alanine (ALT) levels preexisting liver disease, including cirrhosis, in a cohort patients admitted with COVID-19 infection at tertiary care hospital network Bronx, New York. We reviewed...

Background: Mortality in coronavirus disease of 2019 (COVID-19) is associated with increases prothrombotic parameters, particularly D-dimer levels. Many institutions have adopted anticoagulation guidelines, often adjusted for illness severity. We wanted to investigate whether improves survival COVID-19 and if this improvement severity.Methods: To simulate an intention treat clinical trial, we analyzed the effect on mortality therapy chosen first 48 hours hospitalization. 3,625 COVID-19+...

COVID-19 has caused a worldwide illness and New York became the epicenter of in United States from Mid-March to May 2020.To investigate coagulopathic presentation COVID its natural course during early stages surge York. To whether hematologic coagulation parameters can be used assess severity death.Retrospective case study positive inpatients between March 20, 2020-March 31, 2020.Montefiore Health System main hospital, Moses, large tertiary care center Bronx.Adult with tests hospitalized at...

ABSTRACT Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cycle threshold (Ct) has been suggested as an approximate measure of initial viral burden. The relationship Ct at hospitalization and patient mortality not thoroughly investigated. Methods findings We conducted a retrospective study SARS-CoV-2 positive, hospitalized patients from 3/26/2020 to 8/5/2020 who had data within 48 hours admission (n=1044). Only with complete survival discharged (n=774) or died in...

Onboarding is a system frequently used in the corporate world as means of orienting incoming employees to their duties and inculcating workplace values. The program aims facilitate transition into new work roles improve employee retention rates. At Montefiore, we have instituted an onboarding curriculum that given anatomic clinical pathology residents about month prior start residency. includes introductory video series basic histology case studies illustrating laboratory principles. This...

BACKGROUND Short‐ and long‐term effects of mobilization regimens in hematopoietic stem cell granulocyte donors have been well characterized. In this study, we examined the longitudinal changes related to repeat stimulated donation. STUDY DESIGN AND METHODS Complete blood counts for consecutive between October 1994 May 2017 were compared unstimulated donors. Plateletpheresis served as controls. The change precollection white (WBC) these donor groups modeled using a linear mixed‐effects model....

ABSTRACT Importance COVID-19 has caused a worldwide illness and New York become the epicenter of in United States. Currently Bronx highest prevalence per capita York. Objective To investigate coagulopathic presentation COVID its natural course to whether hematologic coagulation parameters can be used assess severity death. Design Retrospective case study positive inpatients between 3/20/2020-3/31/2020. Setting Montefiore Health System main hospital, Moses, large tertiary care center Bronx....

Idiopathic membranous nephropathy is the most common cause of nephrotic syndrome in nondiabetic adults. The antibody often implicated M‐type phospholipase A2 receptor (PLA2R) antibody, found >70% primary cases. First‐line therapy immunosuppressive nature, but for patients who are treatment‐resistant there a significant risk end‐stage renal disease and mortality. Hypercholesterolemia not only side effect syndrome, also its presence may worsen function. A recent single‐arm observational...

.Intraoperative monitoring differs from determination of SEP in the laboratory technique, interpretation and expectations technician. In this article, operating room environment, OR techniques intraoperative changes will be discussed. Representative cases presented which emphasize importance rapid accurate diagnosis. These demonstrate examples injury to peripheral nerve, brachial plexus, spinal cord, brainstem cerebral hemisphere were demonstrated by monitoring.

The authors have disclosed no conflicts of interest.