A5091531128- Acute Myeloid Leukemia Research
- Brain Metastases and Treatment
- Multiple Myeloma Research and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Neutropenia and Cancer Infections
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Retinoids in leukemia and cellular processes
- Chronic Myeloid Leukemia Treatments
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- CNS Lymphoma Diagnosis and Treatment
- Drug-Induced Ocular Toxicity
- Acute Lymphoblastic Leukemia research
- Acute Ischemic Stroke Management
- CAR-T cell therapy research
- Sarcoma Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Cancer Risks and Factors
- Peptidase Inhibition and Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Immunodeficiency and Autoimmune Disorders
- Cancer Immunotherapy and Biomarkers
- Cancer Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
The University of Texas Health Science Center at Houston
2021-2025
Texas Medical Center
2024
Mayo Clinic
2024
WinnMed
2024
Institut Paoli-Calmettes
2023
Kuwait Cancer Control Center
2023
Ain Shams University
2023
The University of Texas MD Anderson Cancer Center
2023
National Research Center for Hematology Russian Academy of Medical Sciences
2023
Actinium Pharmaceuticals (United States)
2023
Balamuthia mandrillaris is a rare cause of granulomatous meningoencephalitis associated with high mortality. We report 69-year-old Caucasian female who presented 3-day history worsening confusion and difficulty speech. On admission, she was disoriented had expressive dysphasia. Motor examination revealed right arm pronator drift. Cerebellar showed slowing finger-nose testing on the left. She HIV-negative, but absolute CD4 count low. Neuroimaging three cavitary, peripherally enhancing brain...
Extraosseous Ewing’s sarcoma is a rare and aggressive malignant tumor with poor prognosis. The pancreas an extremely uncommon primary site, only 27 cases that have been published worldwide. We report 26-year-old female who presented 5 days of left upper quadrant pain, nausea, vomiting. On examination, she was anicteric had epigastric tenderness without guarding, rebound tenderness, or palpable mass. She slightly elevated serum aminotransferase lipase levels. Abdominal computerized tomography...
A man in his 60s presented with a gradual progressive right-sided neck mass. Initial core biopsy was inconclusive and he treated short course of oral prednisone for presumed sarcoidosis. Two months later, the patient developed worsening dysphagia, hoarseness voice, dyspnea, weight loss. Physical examination revealed bilateral cervical right axillary lymphadenopathy. lymph node excisional performed immunohistochemistry diffusely positive OCT4, SALL4, CD117, PLAP, confirming diagnosis...
Immune checkpoint inhibitors (ICIs) have emerged as groundbreaking new therapies for a variety of solid tumors. ICIs stimulate the host immune system to attack cancer cells. However, this nonspecific activation can cause autoimmunity across multiple organ systems-this is referred an immune-related adverse event. Vasculitis secondary ICI administration extremely rare event seen in <1% cases. We identified 2 cases pembrolizumab-induced acral vasculitis at our institution. The first patient,...
Primary lymphoma of the bone (PLB) is a rare lymphoproliferative neoplasm that can present either as solitary or multiple lesions. We report four patients with PLB who were successfully treated R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) followed by consolidative radiotherapy. All achieved complete remission had excellent long-term outcomes. has favorable response to combined modality treatment chemoimmunotherapy radiation. Long-term outcomes tend be better...
The primary objective of our study was to evaluate the effectiveness renal cell carcinoma (RCC) screening in transplant (RT) recipients.Single-centre retrospective study.1998 RT recipients who underwent at Memorial Hermann Hospital (MHH) Texas Medical Center (TMC) between 1 January 1999 and 31 December 2019 were included we identified 16 patients (0.8%) with RCC. An additional four RCC elsewhere but received follow-up MHH TMC also included. Subject races white (20%), black (50%), Hispanic...
To report two high-grade glioma (HGG) cases with extracranial metastases (EXM) pathological review and next-generation sequencing (NGS) data.
Intracerebral hemorrhage is a potentially fatal complication in patients with acute leukemia and contributing factors include thrombocytopenia coagulopathy. Patients may develop subdural hematoma (SDH) spontaneously or secondary to trauma. In SDH, the surgical evacuation of causes significant morbidity mortality. New approaches strategies reduce need for are needed improve outcomes intracerebral hemorrhage. We report two cases SDH successfully treated middle meningeal artery embolization,...
After undergoing hip arthroplasty, the patient had hematoma formation in pelvis, active bleeding from surgical site, and a prolonged activated partial thromboplastin time. Careful evaluation led to diagnosis of an acquired disorder.
Treatment of cancer patients with olaparib (PARP inhibitor) is associated an increased risk anemia, which seen in a majority treated patients. However, symptomatic anemia requiring transfusion rare. Olaparib-induced can be secondary to bone marrow suppression, hemolysis or folate deficiency. We report case new onset severe folic acid deficiency patient breast and relapsed fallopian tube being olaparib. Complete blood count on admission showed hemoglobin 4.2 g/dl serum was undetectable (<...
Drug-associated thrombocytopenia is often unrecognized. We report a 76-year-old female with lymphoma who presented easy bruising and oral bleeding. She had undergone screening for hepatitis B virus (HBV) prior to starting rituximab was found have core serum antibody (IgG anti-HBc). therefore treated prophylactic entecavir 0.5 mg daily prevent reactivation of HBV. Her initial platelet count 136,000/mm3. Five days after entecavir, she bleeding 7,000/mm3. A coagulation profile the rest blood...
e19033 Background: ICH is a devastating and potentially fatal complication in patients with AL. Contributing factors for include thrombocytopenia, hyperleukocytosis, coagulopathy. Acute promyelocytic leukemia (APL) has higher risk of disseminated intravascular coagulation (DIC) ICH, contributing to early deaths from the disease. At our institution, we have incorporated MMA embolization into traditional methods observation surgery management AL patients. Methods: We performed single-center...
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin (NHL); it has a cure rate approximately 50% with standard anthracycline-based chemoimmunotherapy. However, clinical outcomes elderly unfit/frail DLBCL patients remain suboptimal due to poor tolerance anthracycline-containing regimens. Herein, we report series seven unfit who were treated reduced-intensity anthracycline-free chemoimmunotherapy (rituximab, cyclophosphamide, vincristine, and prednisone) regimen...
Mantle cell lymphoma (MCL) is an incurable B non-Hodgkin's with a variable clinical course. Central nervous system (CNS) involvement rare and dreaded complication in MCL. We report case of leptomeningeal relapse MCL that was successfully treated single-agent Bruton's tyrosine kinase inhibitor. A man his 50s six cycles bendamustine-rituximab, achieving complete remission (CR) subsequently placed on rituximab maintenance for 2 years. Four years later, he hospitalised symptoms organic brain...