Abstract Growing evidence suggests a close link between acute kidney injury (AKI) and disruptions in renal microcirculation. However, current non‐invasive tools for quantitatively monitoring structural functional changes microcirculation remain limited, making early diagnosis difficult. To address this challenge, work introduces label‐free 3D multi‐parametric imaging technique that combines photoacoustic super‐resolution ultrasound imaging. This approach provides high‐resolution information...

ABSTRACT Vasant Ramji Khanolkar was the first Professor and Head of Pathology at Seth Gordhandas Sunderdas Medical College King Edward Memorial VII Hospital [GSMC] in Bombay (now Mumbai). Although he later gained international recognition as a pathologist during his career Tata Hospital, Bombay, after 1941, little is known about scientific contributions years GSMC. This article outlines research other academic activities GSMC, with specific dates; memberships societies congresses attended...

Cancer metastasis is quite devastating to the patient as well physician and may herald onset, dissemination or recurrence of malignancy. Breast carcinoma most common encountered by dermatologists it presents in various morphological histological forms. Here, we present two varied cases, first being nodular from a previously treated intraductal second, rarer variant, erysipeloides heralder invasion an incompletely disease.

Abstract Background. Systemic sclerosis is a disease of unknown etiology for which no specific treatment effective. Pulse therapy with corticosteroids has been tried various autoimmune disorders minimal side effects. We undertook this study to determine the efficacy dexamethasone pulse in progressive systemic (PSS). Methods. Five women PSS between ages 30 and 60 years, received 100 mg 500 mL 5% dextrose by slow intravenous infusion over 3 hours consecutive days, once month. Results. All...

Coenurosis, a rare zoonotic disease caused by the larval form of Taenia multiceps (bladderworm) is common in sheep rearing countries, but human infections are rare. Central nervous system involvement produces large giant sized cysts that radiologically closely mimic hydatid cysts. Most resulting cerebral coenuri have been reported from Europe and Africa. We report two cases coenurosis India, first 55-year-old male presenting with cystic lesion right parietooccipital region second occurring...

Subepidermal autoimmune bullous diseases are a diverse group of with overlapping clinical and immunopathological features. Indirect immunofluorescence microscopy on artificially split skin helps to classify these conditions into those staining the epidermal side ("roof-binding") dermal ("floor-binding"). Epidermolysis bullosa acquisita is prototype "floor-binding" subepidermal diseases. However, not all floor-binding sera associated epidermolysis acquisita.The aim this study was evaluate...

A 35-year-old woman presented with raised red lesions over the elbow at site of a prior injury from road traffic accident which had occurred 3 years ago. She gave history pus discharge occasionally. previous biopsy suggested diagnosis cutaneous botryomycosis following patient received course antibiotics for week. culture revealed no bacterial or fungal growth. But continued to progress drainage. On clinical examination, multiple skin-coloured nodules erosions and crusting were seen extensor …

As the outermost and largest organ of human body, skin is constantly exposed to solar radiation, thereby making it important study science interaction radiation with called cutaneous photobiology. The electromagnetic spectrum consists radiations different wavelengths, but impact ultraviolet rays on most studied out all. In this section, we have tried provide a concise overview existing understanding spectrum, principles photons skin, its acute chronic effects.

Abstract Background Exfoliative dermatitis (ED) can result in protein loss due to scaling causing a negative nitrogen balance. Freedberg and Baden ( J Invest Dermatol 1962; 38: 277–284) estimated the amount of scale lost ED by collecting it an occlusive suit. Subsequently, content was determined Kjeldahl method. The exact supplementation ED, dependent on loss, is not well established. As occlusion hyperthermia caused suit inhibit scaling, objectives present study were design alternative...

Bowen's disease is generally regarded as premalignant dermatoses. The affects both skin and the mucosa has potential to progress invasive squamous cell carcinoma. There are descriptions of several histological variants like psoriasiform, atrophic, pagetoid, etc. Acantholysis anaplastic keratinocytes with bullae/cleft formation described in condition actinic keratosis adenoid variant carcinoma, but there lack report describing this phenomena disease. We present a case unusual acantholytic...

Epidermolysis bullosa acquisita (EBA) is an acquired subepidermal bullous disorder characterized by autoantibodies against Type VII collagen. It usually affects adults; childhood EBA rare. We describe a 10-year-old girl presenting with recurrent tense blisters predominantly on legs, dorsa of hands and feet accompanied oral erosions since the age 5 years. Direct immunofluorescence (IF) microscopy showed linear deposition IgG C3 along basement membrane zone (BMZ); indirect IF salt-split skin...

Livedoid vasculopathy with mononeuritis multiplex is a rare association. We are presenting case of an unusual association livedoid multiplex, who developed fulminant hepatic failure which was secondary to Herpes simplex virus (HSV) hepatitis, while she on treatment immunosuppressants. Her skin biopsy and immunofluorescence studies showed the features vasculitis. A from sural nerve chronic