A5100601062- Aluminum Alloy Microstructure Properties
- Hydrogen Storage and Materials
- Solidification and crystal growth phenomena
- DNA and Nucleic Acid Chemistry
- Advanced biosensing and bioanalysis techniques
- Bacteriophages and microbial interactions
- High Temperature Alloys and Creep
- Metallurgical Processes and Thermodynamics
- Nuclear Materials and Properties
- RNA and protein synthesis mechanisms
- Animal Genetics and Reproduction
- Fusion materials and technologies
- RNA Interference and Gene Delivery
- High Entropy Alloys Studies
- Biosensors and Analytical Detection
- Metallurgy and Material Forming
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- DNA Repair Mechanisms
- High-Temperature Coating Behaviors
- Geological Studies and Exploration
- Genomics and Chromatin Dynamics
- Ammonia Synthesis and Nitrogen Reduction
- Catalysis and Hydrodesulfurization Studies
- Geological and Geophysical Studies
- Algebraic Geometry and Number Theory
Central South University
2023-2024
Nanchang University
2024
Institute of Physics
2024
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2022-2024
Southeast University
2024
Shanghai Jiao Tong University
2024
Henan Provincial Institute of Occupational Health
2023-2024
Guangxi Medical University
2023
Sichuan University
2023
Balancing the hardness and electrical conductivity of copper alloys within complex compositions processes poses a formidable challenge. This study proposes strategy combining machine learning with Pareto front techniques to identify optimal combinations composition processing for Cu-xTi (1.5 ≤ x 5.4, in wt.%) alloys. Through thermodynamic calculations, precipitation simulations, experimental characterizations, microstructural evolution β'-Cu4Ti precipitates designed was explored. The...
We report that trivalent cobalt hexammine cations decrease the persistence length, stretching modulus, helical density, and size of plectonemes formed under torque DNA but increase those RNA. Divalent magnesium cations, however, lengths, contour sizes while increasing densities both The experimental results are explained by different binding modes on RNA in our all-atom molecular dynamics simulations. significant variations structures duplexes induced high-valent may affect interactions with...
Electrocatalytic nitrate reduction reaction (NO3RR) to ammonia is deemed as an ideal strategy balance the global nitrogen cycle. However, cycling of active sites by proton transfer highly...
When stretched, both DNA and RNA duplexes change their twist angles through twist-stretch coupling. The coupling is negative for but positive RNA, which not yet completely understood. Here, our magnetic tweezers experiments show that the of reverses from to by multivalent cations. Combining with previously reported tension-induced negative-to-positive reversal DNA, we propose a unified mechanism couplings based on molecular dynamics simulations. Two deformation pathways are competing when...
Gastric cancer is anatomically proximal to peritoneum. peritoneal metastasis a complex biological process which corresponded with disharmony within dysfunctional adipose tissue and metabolism reprogramming. Laminin gamma 1 (LAMC1) highly expressed in cells of metastatic sites, however, the mechanism LAMC1-metiated gastric metastases tissue-rich peritoneum remains unclear. In our study, immunohistochemical staining, single cell sequencing, co-culture model, luciferase reporter, RNA...
CpG methylation of DNA is common in mammalian cells. In sperm, the has highest level and condensed into toroidal structures. How affects structures interactions important to understand its biological roles but largely unknown. Using an RNA–DNA–RNA structure, we observed equilibrium hopping dynamics between extended states presence polyamines or polylysine peptide as a reduced model histone tails. Combing with measured elasticities, report that each cytosine nucleotide substantially increases...
Objective Self-directed learning (SDL) has been embraced by the medical community as a core professional competency, with motivation considered crucial component of SDL. However, little is known about how hospital pharmacists perceive in SDL workplace. This study aimed to examine intrinsic and external Design employed multicentre qualitative design, which lasted 13 months from May 2020 June 2021. The interviews were audiorecorded, transcribed verbatim analysed NVivo V.12.0. Thematic analysis...
ABSTRACT Linker histone H1 plays a crucial role in various biological processes, including nucleosome stabilization, high-order chromatin structure organization, gene expression, and epigenetic regulation eukaryotic cells. Unlike higher eukaryotes, little about the linker Saccharomyces cerevisiae is known. Hho1 Hmo1 are two long-standing controversial candidates budding yeast. In this study, we directly observed at single-molecule level that Hmo1, but not Hho1, involved assembly yeast...
Despite having a great variety of topologies, most DNA, RNA, and RNA–DNA hybrid (RDH) configurations for single-molecule manipulation are composed several single-stranded (ss) DNA ssRNA strands, with functional labels at the two ends surface tethering. On this basis, we developed simple, robust, universal amplification-annealing (AA) assay making all these in or three steps without inefficient digestion ligation reactions. As examples, made ssDNA, short ssDNA double-stranded (ds) handles,...
Objective As lifelong learners, hospital pharmacists must continually improve their self-directed learning skills. Reasonable strategies have been proven to enhance (SDL) significantly. Therefore, this study aims investigate the SDL used by in depth provide them with a reference for development of Setting The was conducted three tertiary hospitals Henan, China. Design and participants This employed multicentre qualitative design lasted 12 months. One-on-one interviews focus group discussions...