A5006013776- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Pluripotent Stem Cells Research
- Peptidase Inhibition and Analysis
- Galectins and Cancer Biology
- Ferroptosis and cancer prognosis
- Immune cells in cancer
- RNA modifications and cancer
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Pancreatic function and diabetes
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Metabolomics and Mass Spectrometry Studies
- Mitochondrial Function and Pathology
- Pancreatic and Hepatic Oncology Research
- Electrospun Nanofibers in Biomedical Applications
Huaian First People’s Hospital
2016-2024
Nanjing Medical University
2016-2024
Dalian Medical University
2013-2015
Dalian Institute of Chemical Physics
2015
Chinese Academy of Sciences
2015
Background and Objective. It is important to guarantee the quality of stem cells. Serial passage main approach expand This study evaluated effects serial on biological characteristics human umbilical cord Wharton's jelly-derived MSCs (WJ MSCs). Methods. Biological properties WJ in early (less than 10 passages, P10), middle (P11-20), late (more P20) phases including cell proliferation, cycle, phenotype, senescence, oncogene expression, stemness marker differentiation capacity were using flow...
Non-small cell lung cancer (NSCLC) is the leading cause of death in smokers and most common for mortality both males females United States. Predisposition this malignancy to distant metastasis leads poor prognosis; therefore, it urgent discover novel therapeutic agents metastatic NSCLC. The present study aimed investigate effects actein treatment on NSCLC growth migration. Cell viability assays demonstrated that administration markedly inhibited proliferation a dose- time-dependent manner....
Cell co-culture plays a key role in inducing the committed differentiation of stem cells vitro, which mimics specific tissue microenvironment vivo by means co-cultured cells. However, present cell systems limit application differentiated due to safety and scale these systems. This study established novel microcapsule system investigated probable effect microencapsulated neural on mesenchymal (MSCs) ex vivo. Mouse bone marrow-derived MSCs were with SHSY5Y alginatepolylysine-alginate (APA)...
Studies have established a correlation between α2-macroglobulin-like 1 (A2ML1) and the prognosis of lung, pancreatic, breast cancers; however, research on its involvement in pathogenesis esophageal carcinoma remains limited. Therefore, this study, we aimed to investigate role A2ML1 progression squamous cell (ESCC). Immunohistochemical staining was employed assess expression level protein both tumor adjacent normal tissues patients with ESCC. The Kaplan–Meier method, along univariate...
Fetal tissue-derived mesenchymal stem cells (MSCs) may offer greater clinical utility because they possess unique properties over bone marrow (BM) MSCs. Although the continuous passage process can generate numerous MSCs for applications, this also have an important effect on bological characteristics of fetal In study, proliferation, stemness and cardiac differentiation umbilical cord (UC) Wharton’s Jelly-derived (WJ MSCs) at different passages (3, 7 14) was investigated. It found that WJ...