A5045020835- Pancreatic function and diabetes
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Advanced Drug Delivery Systems
- Hydrogels: synthesis, properties, applications
- Polymer Surface Interaction Studies
- Tissue Engineering and Regenerative Medicine
- Microbial Community Ecology and Physiology
- RNA Interference and Gene Delivery
- Catalytic C–H Functionalization Methods
- Nanocomposite Films for Food Packaging
- Polar Research and Ecology
- Nanoparticle-Based Drug Delivery
- Synthesis and Catalytic Reactions
- Crystallization and Solubility Studies
- Chemical Synthesis and Analysis
- X-ray Diffraction in Crystallography
- biodegradable polymer synthesis and properties
- Electrohydrodynamics and Fluid Dynamics
- Microencapsulation and Drying Processes
- Advanced biosensing and bioanalysis techniques
- Viral Infectious Diseases and Gene Expression in Insects
- Membrane Separation Technologies
- Polysaccharides and Plant Cell Walls
- Carbon and Quantum Dots Applications
Shanxi Fenyang Hospital
2025
Shanxi Medical University
2025
Ministry of Education of the People's Republic of China
2020-2025
Northwest University
2020-2025
Lanzhou University
2003-2024
Shandong Agricultural University
2024
Minzu University of China
2024
Guilin Medical University
2021-2024
Zhengzhou University
2024
State Ethnic Affairs Commission
2024
Aerobic exercise exerts a significant impact on the gut microbiota imbalance and atherosclerosis induced by high-fat diet. However, whether fecal transplantation, based aerobic exercise, can improve progression remains unexplored. In this study, we utilized male C57 mice to establish models of atherosclerosis, followed transplantation(Fig 1a). Firstly, analyzed body weight, somatotype, adipocyte area, aortic HE images model mice. Our findings revealed that diet -induced exhibited elevated...
Microencapsulation provides a simple and cost-effective way to enclose bioactive materials, such as drugs cells, within semi-permeable polymeric membrane for the purpose of protecting materials releasing enclosed substances or their products in controlled fashion. This article presents an overview microencapsulation biomedical applications, with focus on progress accomplished our laboratory. After description chemistry properties natural polysaccharide-based microcapsules, applications drug...
Conventional approaches on using hydroxylamine derivatives as single nitrogen sources, for the construction of n-membered (n > 3) N-heterocycles, rely upon two chemical operations by involving sequential nucleophilic and electrophilic C–N bond formations. Here, we report a highly efficient cascade alkyne insertion/C–H activation/amination rapid preparation myriad tricyclic indoles, in single-step transformation, bifunctional secondary hydroxylamines. It is noteworthy that judicious selection...
In this study, an in vitro multicellular tumor spheroid model was developed using microencapsulation, and the feasibility of microencapsulated (MMTS) to test effect chemotherapeutic drugs investigated. Human MCF-7 breast cancer cells were encapsulated alginate-poly-l-lysine-alginate (APA) microcapsules, a single 150 mum diameter formed microcapsule after 5 days cultivation. The cell morphology, proliferation, viability MMTS characterized phase contrast microscopy, BrdU-labeling, MTT stain,...
Novel amphiphilic chitosan derivatives (glycidol−chitosan−deoxycholic acid, G-CS-DCA) were synthesized by grafting hydrophobic moieties, deoxycholic acid (DCA), and hydrophilic glycidol, with the purpose of preparing carriers for poorly soluble drugs. Based on self-assembly, G-CS-DCA can form nanoparticles size ranging from 160 to 210 nm, maintained stable structure about 3 months when stored in PBS (pH 7.4) at room temperature. The critical aggregation concentration decreased 0.043 mg/mL...
A simple approach of a mitochondria-targeted fluorescent probe has been demonstrated for the preparation highly water-soluble and TPP-conjugated carbon dots (TPP-CDs) derived from low-cost citric acid urea. We found that TPP-CDs are suitable both one- two-photon mitochondria-selective imaging in living cells.
Abstract Quorum sensing (QS) is a process that enables bacteria to communicate using secreted signaling molecules, and then makes population of regulate gene expression collectively control behavior on community-wide scale. Theoretical studies efficiency have suggested both mass-transfer performance in the local environment spatial distribution cells are key factors affecting QS. Here, an experimental model based hydrogel microcapsules with three-dimensional structure was established...
Alginate-poly-l-lysine-alginate (APA) microcapsules have proven effective in protecting enclosed live cells from immune rejection following transplantation into experimental animals, thereby eliminating the need for immunosuppressive therapy. However, order capsules to remain intact extended periods vivo, thickness of membrane material must be optimized. In this study, was examined as an indicator strength and measured under different reaction conditions. The found increase 1) 4.6μm 6.6μm...
An efficient and convenient one-pot domino reaction for the direct synthesis of pyrrolo[1,2-a]quinoxalines has been developed. This approach utilizes an imine formation reaction, SEAr cleavage C-C bonds catalyzed by a Brønsted acid. β-Diketones β-keto esters are both well tolerated to give corresponding products in moderate excellent yields.
We report a strategy to synthesize self-healing hydrogels <italic>via</italic> exploiting endothermic interactions between polyelectrolytes.