A5053986310- Anesthesia and Sedative Agents
- Orthodontics and Dentofacial Orthopedics
- Temporomandibular Joint Disorders
- Anesthesia and Pain Management
- Anesthesia and Neurotoxicity Research
- Pain Mechanisms and Treatments
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- dental development and anomalies
- Oral and Maxillofacial Pathology
- Craniofacial Disorders and Treatments
- Neuropeptides and Animal Physiology
- Cancer, Stress, Anesthesia, and Immune Response
- Dental Implant Techniques and Outcomes
- Pharmacological Receptor Mechanisms and Effects
- Neuroscience of respiration and sleep
- Veterinary Pharmacology and Anesthesia
- Bone Tumor Diagnosis and Treatments
- Tracheal and airway disorders
- Dental Radiography and Imaging
- Cleft Lip and Palate Research
- Ion channel regulation and function
- Nicotinic Acetylcholine Receptors Study
- Facial Trauma and Fracture Management
Saitama Medical University Hospital
2014-2024
Yokohama City University Hospital
2024
Yokohama City University
2024
Seirei Hamamatsu General Hospital
2022
Saitama Medical University
1994-2022
Gifu University
2022
Renewable Energy Systems (United Kingdom)
2022
Weatherford College
2019-2020
Meikai University
2003-2014
National Hospital Organization
1990-2014
The antihyperalgesic properties of the opiate antidiarrheal agent loperamide (ADL 2-1294) were investigated in a variety inflammatory pain models rodents. Loperamide exhibited potent affinity and selectivity for cloned micro (Ki = 3 nM) compared with delta 48 kappa 1156 human opioid receptors. potently stimulated [35S]guanosine-5'-O-(3-thio)triphosphate binding (EC50 56 nM), inhibited forskolin-stimulated cAMP accumulation (IC50 25 Chinese hamster ovary cells transfected mu receptor....
The skeletal anchorage system (SAS) was developed to provide intraoral absolute for the intrusion or distalization of molars. purpose this study verify effects remarkable molar on tooth root and maxillary sinus floor. Six adult female beagles with fully erupted dentition were used. Titanium miniplates implanted bilaterally above second premolar apices using pentobarbital anesthesia. premolars intruded four seven months after three healing implantation. Standardized dental radiographs taken...
With Duchenne muscular dystrophy (DMD) being the most common and severe type of dystrophy, DMD patients are at risk for complications from general anesthesia due to impaired cardiac respiratory functions as pathological condition progresses. In recent years, advances in multidisciplinary treatment have improved prognosis patients, number requiring surgery has increased. Remimazolam is a benzodiazepine derivative similar midazolam. Its circulatory stability fact that it an antagonist make...
The skeletal anchorage system (SAS) was developed as intraoral rigid anchors for open-bite correction by intrusion of molars. Since the application SAS is a new modality in orthodontic treatment, influences radical molar on root and inferior alveolar neurovascular bundle were unknown. purpose this research to verify effect bundle, level osseointegration bone screws, resorption. results study showed mandibular molars intruded 3.4 mm average over 7 months dogs. miniplates well stabilized with...
Background Three types of opioid receptors, mu, delta, and kappa, are present in the periphery central nervous system. In contrast to effects system, antinociceptive action opioids is not as well characterized. The intraarticular, spinal, intramuscular injections kappa agonists on autonomic response evoked by compression an inflamed knee joint were evaluated. Methods halothane-anesthetized rats, arthritis was induced injecting kaolin carrageenan into right joint. Standardized inflation a...