A BSTRACT Introduction: This study was undertaken to assess the distribution of ganglion cells (GCs) and interstitial Cajal (ICCs) across different points distal rectal pouch in anorectal malformation (ARM) patients over three stages repair. We hypothesize that along with surgical factors, there could be intrinsic factors as well which can cause dysmotility these after Methodology: Full-thickness colonic biopsy specimens were taken from proximal stoma, 21 boys aged 0–8 months undergoing 3...

To compare the safety profiles of biosimilar ranibizumab (Razumab™) and innovator (Accentrix™) in management chorioretinal vascular diseases across a large, diverse patient cohort multicenter retrospective study. This multicenter, study analyzed data from 39,226 eyes treated with either or 21 centers India between January 2016 March 2024. Eligible patients received intravitreal injections for conditions including age-related macular degeneration (AMD), diabetic edema (DME), retinal vein...

A BSTRACT Vaginal duplication cysts are rare congenital anomalies, especially in pediatric patients, often mimicking other pelvic cystic lesions. We report a 2-month-old female with lower abdominal lump, urinary retention, and defecation issues. Imaging suggested rectal cyst, but laparoscopy revealed vaginal cyst adherent to the posterior wall. Surgical excision confirmed diagnosis, child had complete symptom resolution. This case emphasizes rarity of infancy importance surgical management...

Pemphigus is a group of bullous disorders the skin characterized by formation autoantibodies present in intercellular junction epidermis. Diagnosis made clinical, histopathological examination, and DIF. As DIF needs frozen sections, fluorescent tagged antibodies, UV light microscope for trained personnel, its non-availability makes definitive diagnosis challenging.

Purpose To evaluate the short-term efficacy and safety of intravitreal bevacizumab in myopic choroidal neovascularization (mCNV). Methods In this noncomparative, consecutive, interventional case series, 12 eyes 11 patients with mCNV without any previous treatment were included. Patients received (1.25 mg/0.05 mL) at baseline 4 weeks interval, if optical coherence tomography (OCT) showed presence intraretinal edema, subretinal fluid, and/or pigment epithelial detachment. followed up for a...

Malignant peripheral nerve sheath tumor is a rare soft tissue sarcoma of ectomesenchymal origin. It the malignant counterpart benign tumors like neurofibromas and schwannomas may often follow them. Common sites include deeper tissues, usually in proximity trunk. Breast an extremely location this lesion presentation as breast lump absence pain or previous neural even rarer. A 38-year-old female presented with complaints painless, hard for three months which was clinically suspected to be...

Malignant transformation of a mature cystic teratoma (MCT) is very rare complication with an incidence 0.17-2%;. The most common form malignant the MCT squamous cell carcinoma. Other tumors arising in include basal carcinoma, sebaceous tumor, melanoma, adenocarcinoma, sarcoma, and neuroectodermal tumor. However metastatic deposits omentum extremely rare. present case highlights rarity occurrence omental transformation.

Sex cord tumor with annular tubules (SCTATs) is a relatively rare ovarian neoplasm often having syndromic association Peutz-Jeghers syndrome (PJS). Other associations described this include adenoma malignum of cervix, Turners syndrome, dysgerminoma, gonadoblastoma, endometrial carcinoma, and endometriosis fallopian tube. We describe for the first time to best our literature search incidental detection SCTAT coexisting an endometriotic cyst ovary. Meticulous histological scanning awareness...

Breast lump as a presenting manifestation of acute lymphoblastic lymphoma (ALL) leukemia is extremely rare. We report case young female who presented with breast clinically suggestive fibroadenoma. On fine needle aspiration cytology, it was diagnosed lymphoid malignancy, later confirmed ALL using hematological investigations.

To examine and subtype cutaneous lymphoma specimens for diagnosis.Aspiration smears from skin lesions lymph nodes diagnosed as non-Hodgkin's (NHL) on cytology in 6 cases over a period of 1 year were reviewed. Two follow-up nodal receiving chemotherapy, during which they developed lesions. In 4, the patients had presenting manifestation. Cytologic findings correlated with histologic hematologic immunocytochemical markers subtyping.Patients ranged 14 to 50 years, equal sex ratio. All presented...

Aggressive angiomyxoma is a rare, locally aggressive soft tissue tumor that has high propensity for local recurrence. It involves mainly the pelvis, vulva, perineum, vagina and urinary bladder in adult women reproductive age. Considering its nature, appropriate management long-term follow-up necessary. We describe case of 22-year-old young pregnant patient presenting with large pedunculated swelling on left labia majora.

Multicystic dysplastic kidney (MCDK) is defined as the presence of multiple noncommunicating cysts various sizes, detected sonographically, without evidence functioning renal parenchyma on dimercaptosuccinic acid scan. It has an incidence 1:4000 live births. They are more commonly diagnosed in boys, usually left side, but may also be bilateral. There primitive ducts surrounded by fibromuscular connective tissue. These because disturbed connection ureteric bud with blastema and abnormal...

Intussusception is a relatively common cause of intestinal obstruction in children but rare, and uncommon clinical entity adults accounting for 1%. Lipoma accounts 4% all benign tumors the gut. Most these are seen large intestine, usually submucosal around ileocecal valve. These often asymptomatic. Though lesions benign, it continues to present difficulties preoperative differentiation between malignant colonic neoplasm. Gastroenterol Res. 2010;3(5):229-231 doi: https://doi.org/10.4021/gr232e

Primary Breast Sarcomas (PBS) are rare malignancies and seen in less than <1 % of all breast malignancies. PBS non epithelial, composed mesenchymal mammary tissue difficult to diagnose from other sarcomas arising breast.A retrospective study was conducted the Department Pathology slides over a period 5 years were reviewed. Out total 1570 malignancies, cases reported as PBS. Diagnosis made on basis Histopathology IHC findings.Out cases, diagnosed (i.e. 0.32% cases). 3 out males comprising 60%...

Mucormycosis of the gut in neonates is rare, difficult to recognize and hence usually fatal. These cases are diagnosed initially as necrotizing enterocolitis (NEC), which leads a delay specific treatment. We present case neonatal gastrointestinal tract (GIT) mucormycosis 2-day-old infant following laparotomy resection for presumptive NEC, together with review GIT newborn babies literature.