William J. Kassler

ORCID: 0000-0003-0238-0898
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • Adolescent Sexual and Reproductive Health
  • Reproductive tract infections research
  • HIV, Drug Use, Sexual Risk
  • Healthcare Policy and Management
  • Syphilis Diagnosis and Treatment
  • COVID-19 epidemiological studies
  • Data-Driven Disease Surveillance
  • Primary Care and Health Outcomes
  • HIV Research and Treatment
  • Homelessness and Social Issues
  • Public Health Policies and Education
  • Patient Satisfaction in Healthcare
  • Healthcare cost, quality, practices
  • Global Public Health Policies and Epidemiology
  • COVID-19 Digital Contact Tracing
  • Emergency and Acute Care Studies
  • Mental Health and Patient Involvement
  • Health disparities and outcomes
  • Gender, Labor, and Family Dynamics
  • Taxation and Compliance Studies
  • Chronic Disease Management Strategies
  • Reproductive Health and Contraception
  • Community Health and Development
  • HIV/AIDS drug development and treatment

Kansas Department of Health and Environment
2025

EPIR Technologies (United States)
2021-2023

Rhode Island Department of Health
2023

IBM (United States)
2019-2022

Centers for Medicare and Medicaid Services
2012-2016

Institute for Community Health
2005

Cheshire Medical Center
2005

Harborview Medical Center
2002

National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
1999-2000

Centers for Disease Control and Prevention
1992-2000

In October 2008, the Centers for Medicare and Medicaid Services (CMS) discontinued additional payments certain hospital-acquired conditions that were deemed preventable. The effect of this policy on rates health care–associated infections is unknown.

10.1056/nejmsa1202419 article EN New England Journal of Medicine 2012-10-11

To determine whether the simultaneous, partial repeal of needle prescription and drug paraphernalia laws in Connecticut affected purchasing usage needles syringes (syringes) by injecting-drug users (IDUs) risk needlestick injuries to police officers, we conducted two serial cross-sectional surveys with IDUs recruited treatment centers, correctional facilities, health department settings. Reports among Hartford officers were reviewed before after new laws. Among who reported ever sharing a...

10.1097/00042560-199509000-00012 article EN Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology 1995-09-01

Background: New rapid HIV antibody tests have allowed provision of results and result-specific counseling on the day initial visit, potential to increase efficiency testing. Methods: To evaluate use testing with same-day in public clinics, Single Use Diagnostic System HIV-1 assay was used for a 3-month period at an anonymous clinic sexually transmitted disease (STD) Dallas, Texas. Non-reactive test were reported as HIV-negative. Reactive 'preliminary positive'. These procedures compared...

10.1097/00002030-199708000-00014 article EN AIDS 1997-07-01

Background and Objectives: Screening tests for detection ofChlamydia trachomatisinclude those processed in laboratories designed to be at the point of care. The latter can yield results time initial patient visit, but most available lab-processed have greater sensitivity. In settings where a proportion patients do not return treatment after positive test results, less sensitive rapid could lead more cost-effective. Goal this Study: To determine situations, if any, which might cost-effective...

10.1097/00007435-199904000-00010 article EN Sexually Transmitted Diseases 1999-04-01

This article presents evidence that sexually transmitted disease (STD) rates are responsive to increases in alcohol taxes and the drinking age. The presumed relationship is a more restrictive policy reduces consumption, which turn decreases risky sexual activity. Reduced‐form regressions of STD on state for years 1981—95 (with controls year) indicate $1 increase per‐gallon liquor tax gonorrhea by 2.1 percent, beer $.20 per six‐pack 8.9 with similar though pronounced effects syphilis rates....

10.1086/467453 article EN The Journal of Law and Economics 2000-04-01

The use of herbs has been advocated as an alternative treatment strategy for human immunodeficiency virus-related illness. To describe the medicinal among acquired syndrome clinic patients and to investigate possible toxic effects, we interviewed 114 randomly selected attending a university-based performed structured review literature identify potential adverse effects herbal use. Twenty-five participants (22%) reported using one or more products in past 3 months. Of those taking herbs, six...

10.1001/archinte.1991.00400110123024 article EN Archives of Internal Medicine 1991-11-01

BACKGROUND: Health care–associated infections (HAIs) are harmful and costly can result in substantial morbidity for hospitalized children; however, little is known about national trends HAIs neonatal pediatric populations. Our objective was to determine the incidence of among a large sample hospitals United States caring critically ill children from 2007 2012. METHODS: In this cohort study, we included NICUs PICUs located reporting data Centers Disease Control Prevention’s National...

10.1542/peds.2014-0613 article EN PEDIATRICS 2014-09-09

Though the Centers for Medicare and Medicaid Services focuses primarily on health care delivery its beneficiaries, it is working at practice, delivery-system, broader-population levels to encourage incremental progress toward population health.

10.1056/nejmp1406838 article EN New England Journal of Medicine 2015-01-07

Rapid, on-site HIV testing with same-day results may improve services and increase the number of clients who learn their serostatus in developing countries. To validate test performance under field conditions assess change proportion serostatus, we conducted a trial using Capillus HIV-1/HIV-2 assay (Cambridge Diagnostics) at AIDS Information Centre counselling sites Uganda. Compared to standard 2-EIA algorithm, sensitivity was 99.6% (95% CI; 98.5%, 99.9%), specificity 98.8% 98.1%, 99.3%),...

10.1258/0956462981921882 article EN International Journal of STD & AIDS 1998-03-01

Azithromycin, an approved single-dose therapy for cervical chlamydia infections, costs four times as much doxycycline, the standard multidose theapy.This study examined whether azithromycin is cost effective treating infections.Two diagnostic strategies were compared: 1) laboratory confirmation of chlamydia, and 2) presumptive diagnosis from perspective healthcare system publicly funded clinic.From perspective, per case pelvic inflammatory disease prevented with ranges a savings $3,502 to...

10.1097/00007435-199509000-00002 article EN Sexually Transmitted Diseases 1995-09-01

To determine what factors distinguish medical students who choose primary care careers, 381 graduating at eight New England schools were surveyed by questionnaire prior to the 1988 National Resident Matching Program. Students asked indicate degrees of influence that various had on their specialty choices, using a Likert-type scale ranging from "totally unimportant" "decisive." Compared with peers chose high-technology specialties, those more likely be motivated opportunities provide direct...

10.1097/00001888-199101000-00012 article EN Academic Medicine 1991-01-01

Objectives. To characterize recent HIV seroconverters in a sexually transmitted disease (STD) clinic population, and examine changing transmission patterns. Methods. We conducted case-control study nested within retrospectively defined cohort of individuals attending Baltimore STD clinics between January 1988 July 1990. Seroconverters, who tested HIV-positive after having negative test, were compared to both HIV-negative controls, also twice, second, prevalent control group. Controls matched...

10.1097/00002030-199403000-00009 article EN AIDS 1994-03-01

Rapid, on-site human immunodeficiency virus (HIV) testing has the potential to improve delivery of prevention services in publicly funded counseling and sites. The Single Use Diagnostic System (SUDS) HIV-1 is only rapid enzyme immunoassay (EIA) approved for diagnostic use United States. To evaluate feasibility using SUDS public clinics validate test's performance a health laboratory, we conducted blinded on plasma sent HIV testing. From 19 March through 30 June 1993, 1,923 consecutive...

10.1128/jcm.33.11.2899-2902.1995 article EN Journal of Clinical Microbiology 1995-11-01

Identify how novel datasets and digital health technology, including both analytics-based artificial intelligence (AI)-based tools, can be used to assess non-clinical, social determinants of (SDoH) for population improvement. A state-of-the-art literature review with systematic methods was performed on MEDLINE, Embase, the Cochrane Library databases grey identify recently published articles (2013-2018) evidence-based qualitative synthesis. Following single titles abstracts, two independent...

10.5210/ojphi.v13i3.11081 article EN cc-by Online Journal of Public Health Informatics 2021-12-24

To determine the frequency and predictors of receipt HIV test results.Analysis responses from 19,127 adults in 1994 16,848 1995 surveyed for U.S. National Health Interview Survey, using logit models to factors independently associated with decreased likelihood receiving results.Overall, 12.5% (+/-1.0%) persons tested 13.3% (+/-0.9%) had not received their results. Those whose was self-initiated were significantly less likely (p<.05) receive The proportion who did results lowest among sought...

10.1097/00126334-199912010-00011 article EN JAIDS Journal of Acquired Immune Deficiency Syndromes 1999-12-01

BACKGROUND Policymakers may wish to align healthcare payment and quality of care while minimizing unintended consequences, particularly for safety net hospitals. OBJECTIVE To determine whether the 2008 Centers Medicare Medicaid Services Hospital-Acquired Conditions policy had a differential impact on targeted healthcare-associated infection rates in compared with non–safety DESIGN Interrupted time-series design. SETTING AND PARTICIPANTS Nonfederal acute hospitals that reported central...

10.1017/ice.2015.38 article EN Infection Control and Hospital Epidemiology 2015-03-03

Readers are invited to submit letters for publication in this department. Submit online at http://joem.edmgr.com. Choose "Submit New Manuscript." A signed copyright assignment and financial disclosure form must be submitted with the letter. Form available www.joem.org under Author Reviewer information. To Editor: Disasters often stress economy and, as case of current pandemic, expose structural weaknesses that reveal significant gaps organization, infrastructure, capacity. From time its...

10.1097/jom.0000000000001955 article EN Journal of Occupational and Environmental Medicine 2020-07-07

Because syphilis can raise the likelihood of HIV transmission and acquisition, prevention in USA has potential benefit reducing number new cases HIV. We developed a simplified model to estimate annual cost new, heterosexually-acquired attributable syphilis.We estimated heterosexual, serodiscordant partnerships which was present 1996. The included probability (with without presence syphilis) other parameters based on data from recent literature. Published direct costs (HIV treatment including...

10.1097/00002030-199907300-00017 article EN AIDS 1999-07-01

Background and Objectives: Partner notification is an important strategy for prevention ofChlamydia trachomatisinfection pelvic inflammatory disease (PID). PID can be prevented by early diagnosis treatment of the female sex partners men infected withC. trachomatis(strategy 1) preventing reinfection in women through their male (strategy 2). Study Design: Using a decision model, cost-effectiveness strategies 1 2 was compared to no partner notification. Outcomes were measured cases net costs...

10.1097/00007435-199705000-00010 article EN Sexually Transmitted Diseases 1997-05-01

Background. The Centers for Medicare and Medicaid Services (CMS) implemented a policy in October 2008 to eliminate additional payment mediastinitis following coronary artery bypass graft (CABG) surgery. Objective. To evaluate the impact of this on rates, using claims National Healthcare Safety Network (NHSN) prospective surveillance data. Methods. We used an interrupted time series design compare rates before after policy, adjusted secular trends. Billing came from inpatient 638,761 CABG...

10.1086/674861 article EN Infection Control and Hospital Epidemiology 2013-12-24
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