A5083641001- Medical and Biological Sciences
- Spaceflight effects on biology
- Industrial Engineering and Technologies
- Polymer Science and Applications
- Tribology and Wear Analysis
- Syphilis Diagnosis and Treatment
- Material Properties and Applications
- Polymer Nanocomposite Synthesis and Irradiation
- Pharmacological Effects of Medicinal Plants
- HIV, TB, and STIs Epidemiology
- Tea Polyphenols and Effects
- Diverse Scientific Research in Ukraine
- Non-Destructive Testing Techniques
- Historical Medical Research and Treatments
- Mechanical Systems and Engineering
- Drug Solubulity and Delivery Systems
- Nanoparticle-Based Drug Delivery
- Engineering Diagnostics and Reliability
- Sarcoidosis and Beryllium Toxicity Research
- Biopolymer Synthesis and Applications
- Cerebrospinal fluid and hydrocephalus
- Diagnosis and treatment of tuberculosis
- Belt Conveyor Systems Engineering
- Hydrogels: synthesis, properties, applications
- Protein Interaction Studies and Fluorescence Analysis
Poltava State Medical University
2021-2024
Ukrainian Medical Stomatological Academy
2018-2020
The State Scientific Research Institute of Civil Aviation
1966
A kombucha multimicrobial culture (KMC) was exposed to simulated Mars-like conditions in low Earth orbit (LEO). The study part of the BIOlogy and Mars EXperiment (BIOMEX), which accommodated European Space Agency's EXPOSE-R2 facility, outside International Station. aim investigate capability a KMC microecosystem survive LEO. During 18-month exposure period, desiccated samples, represented by living cellulose-based films, were subjected anoxic ultraviolet (UV) radiation, as prevalent at...
Outer-membrane vesicles (OMVs), produced by nonpathogenic Gram-negative bacteria, have potentially useful biotechnological applications in extraterrestrial extreme environments. However, their biological effects under the impact of various stressors to be elucidated for safety reasons. In spaceflight experiment, model biofilm kombucha microbial community samples, which Komagataeibacter intermedius was a dominant community-member, were exposed simulated Martian factors (i.e., pressure,...
Based on statistical and literary data, the article presents an epidemiological analysis of incidence sexually transmitted infections in Ukraine over a long period time (1945—2017) with special emphasis syphilis gonorrhea. Focus is made changes factors characteristic each sociohistorical period. Despite significant reduction gonorrhea since 1989, there concern about possibility new increase spread these infections, associated decrease public health authorities' attention to important...
Despite the significant advances in modern medicine, issue of differential diagnosis diseases bronchopulmonary system remains a complex and urgent problem practical work physicians.Of particular importance are pathological processes that part "pulmonary dissemination syndrome", which, according to literature, includes more than 200 diseases.Most them not common clinical practice, but this syndrome also pulmonary dissemination, which is most practice.These include focal pneumonia,...
Hydrophobic spin-labeled carboline and a number of steroids dissolve well in both pure PEG aqueous solutions, demonstrating the presence triplet EPR spectrum. It was shown that introduction 20% solutions mol. m. from PEG-200 to PEG-40,000, hydrophobic spin labeled progesterone or cavity SAB is effectively displaced into solution bovine serum albumin (SAB) by competing with SAB. Polyethylene glycols demonstrate full biocompatibility even biological structures and, as enhancers, are universal....
The increase in resistance of pathogenic microflora to antibiotics over the world has become one challenges for biomedical science. Therefore, further development antimicrobials and their use various fields medicine are extremely important. There a wide range antiseptic preparations different clinical (octenisept, eludril, triclosan, myramistin, chlorhexidine, bigluconate-syn. hexinone, hibiscrab, hibitsan, eugel, fervex others) our country today. In 1985 researchers Department Skin Sexually...
The pharmacokinetics of nitazole was studied after oral administration to rabbits in the form a suspension or tablets together with number natural and modified polysaccharides. obtained curves demonstrate variety pharmacokinetic profiles: for carboxymethyl starch, rapid absorption is observed (Tmax=15 min), concentration plasma an order magnitude higher than bioavailability 98 %, as intravenous administration; nitazol dialdehyde Tmax = 1 hour observed, gradual elimination T0.5 7.4...
Cidipol is a combination drug in the form of solution chlorinebrown aldehyde dimexide and polyethylene glycol (PEG-400).Objective — to study pharmacokinetics Сidipol while rectal dermal application, as also evaluate features its metabolism body animals.Materials methods. Experiments were carried out on rabbits chinchilla breed (six animals for each route administration) which blood plasma was examined by gas chromatography (GC) at certain intervals after administration drug.Results...
Інтегративні зв'язки і параметри надання медичної допомоги пацієнтам дерматовенерологічного профілю на рівні первинної ланки В. Г. Кравченко 1 , І. Степаненко 2 М. Волкославська 3 Б. Попова Л. Рощенюк 4 П

 Pegylated liposomal anticancer drugs, in particular, doxorubicin have an expansion of the spectrum toxicity. To study mechanisms influence polyethylene glycol (PEG) on structure cell membranes, sensitive biophysical method spin probes was used. Using probe method, it has been shown that presence increased prothrombin blood index, viscosity and a high density red cells other components, large long fragments PEG molecules located surface pegylated delivery systems can effectively...
Topicality. Placenta-based cosmetics are widely used all over the world.Aim. To investigate composition of water-soluble porcine placenta fractions and to study similarity their components model membranes.Materials methods. The molecular weight distribution VESP was studied by high-performance gel permeation chromatography. Molecular weights were determined retention time on column reference substances. peptides for liposome membranes with phosphatidylcholine, method fluorescent probes...
Objective — to determine the scope and algorithm of cooperation between dermatovenereologists family medicine doctors in providing medical services for skin diseases sexually transmitted infections (STIs).Materials methods. Analysis dynamics incidence Ukraine virtual creation an epidemiological situation absence integration relations individual health services.Results discussion. The algorithm, rational approaches provision patients at primary specialized level are offered. Diagnosis...
Objective — to draw the attention of Ukrainian health care management, National Health Care Service (NHCS) and dermatovenereologists urgent issues reforming industry, identifying shortcomings in reform presenting views experienced professionals on correcting organizational measures.Official statistics was used based materials leading specialists Kharkiv Research Institute Dermatology Venereology, scientific practical institutions Ukraine, forecast «GlobalData» analytical statistical company...