Yongliang Zhang

ORCID: 0000-0003-0244-912X
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About
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Research Areas
  • Bioactive natural compounds
  • Bioactive Natural Diterpenoids Research
  • Natural product bioactivities and synthesis
  • Chemical Synthesis and Analysis
  • Geophysics and Gravity Measurements
  • Phytochemistry and Biological Activities
  • Steroid Chemistry and Biochemistry
  • Ionosphere and magnetosphere dynamics
  • Phytochemical Studies and Bioactivities
  • Phytochemical compounds biological activities
  • Growth Hormone and Insulin-like Growth Factors
  • Mitochondrial Function and Pathology
  • Microbial Metabolites in Food Biotechnology
  • Cancer, Hypoxia, and Metabolism
  • Plant biochemistry and biosynthesis
  • Virus-based gene therapy research
  • Geomagnetism and Paleomagnetism Studies
  • Boron Compounds in Chemistry
  • Medicinal Plants and Bioactive Compounds
  • Supramolecular Chemistry and Complexes
  • Pancreatic function and diabetes

Shandong University
2023

Johns Hopkins University Applied Physics Laboratory
2022

Logistics University of People's Armed Police Force
2012-2019

Chinese People's Armed Police Force
2012-2019

Huazhong University of Science and Technology
2015

South China Agricultural University
2008

Chinese People's Armed Police Force Medical College Affiliated Hospital
2008

As a pair of differential isomers, Kaji-ichigoside F1 and Rosamultin are both pentacyclic triterpenoids isolated from the subterranean root Potentilla anserina L., plant used in folk medicine western China as antihypoxia anti-inflammatory treatments. We demonstrated that effectively prevented hypoxia-induced apoptosis vascular endothelial cells. established hypoxia model, using EA.hy926 cells, to further explore mechanisms. Hypoxia promoted phosphorylation AKT, ERK1/2, NF- κ B. In hypoxic...

10.1155/2020/6837982 article EN cc-by Oxidative Medicine and Cellular Longevity 2020-03-30

In the space physics community, processing and combining observational modeling data from various sources is a demanding task because they often have different formats use coordinate systems. The Python package GeospaceLAB has been developed to provide unified, standardized framework process data. composed of six core modules, including DataHub as manager, Visualization for generating publication quality figures, Express higher-level interfaces , SpaceCoordinateSystem system transformations,...

10.3389/fspas.2022.1023163 article EN cc-by Frontiers in Astronomy and Space Sciences 2022-12-07

The alcohol and n-butanol extract of Potentilla anserine L. significantly protects myocardium from acute ischemic injury. However, its effects on rat hippocampal neurons the mechanism protection remain unclear. In this study, primary cultured neonatal rats were incubated in 95% N2 5% CO2 for 4 hours. Results indicated that hypoxic injury decreased viability neurons, increased expression levels caspase-9 caspase-3 mRNA, as well cytochrome c, Caspase-9, Caspase-3 protein. Pretreatment with...

10.3969/j.issn.1673-5374.2012.33.002 article EN PubMed 2012-11-25

Eq-4-O-acyl group directed β-rhamnosylation and β-mannosylation are achieved in carborane or BARF anion formed weakly nucleophilic environment with the assistance of a 2,3-orthocarbonate group. The 4-O-acyl plays critical role directing β-selectivity, coordinating is essential to amplify this direction. orthocarbonate could be readily removed 1,3-propanediol presence BF3.Et2O.

10.26434/chemrxiv-2023-sg04q preprint EN cc-by-nc-nd 2023-08-04

Somatostatin (SS) and growth hormone-releasing hormone (GHRH) are synthesized secreted by the hypothalamus, which can control synthesis secretion of (GH) from hypophysis as well regulate GH concentrations in animals humans. In this article, we describe regulation animal using plasmid DNA encoding both GHRH gene SS fused with hepatitis B surface antigen (HBsAg) gene. We constructed a series expression plasmids to express HBsAg-SS fusion genes individually collectively. The were successfully...

10.1080/10495390801888328 article EN Animal Biotechnology 2008-04-17

Rosamultin is a major active pentacyclic triterpenoid saponin isolated from the root of <italic>Potentilla anserina</italic> L., which has various pharmacological activities.

10.1039/c9ay01419e article EN Analytical Methods 2019-01-01
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