- Stability and Control of Uncertain Systems
- Gut microbiota and health
- Structural Health Monitoring Techniques
- Clostridium difficile and Clostridium perfringens research
- Fault Detection and Control Systems
- Neural Networks Stability and Synchronization
- Hydraulic and Pneumatic Systems
- Metabolomics and Mass Spectrometry Studies
- Liver Disease Diagnosis and Treatment
- Robotic Locomotion and Control
- Immune Response and Inflammation
- Mechanical and Optical Resonators
- Advanced MIMO Systems Optimization
- Robotic Path Planning Algorithms
- Vibration Control and Rheological Fluids
- Energy Harvesting in Wireless Networks
- Advanced Wireless Network Optimization
- Elasticity and Wave Propagation
- Machine Fault Diagnosis Techniques
- Blind Source Separation Techniques
- Probiotics and Fermented Foods
- Adaptive Control of Nonlinear Systems
- Control Systems and Identification
- Control and Dynamics of Mobile Robots
- Bioactive Natural Diterpenoids Research
First People's Hospital of Yunnan Province
2022-2024
Kunming University of Science and Technology
2020-2024
Shanghai Electric (China)
2023
Chinese People's Armed Police Force
2020-2023
Chinese People's Armed Police General Hospital
2020-2023
Institute of Microbiology
2017-2023
Huawei Technologies (China)
2023
Hong Kong Polytechnic University
2017-2022
City University of Hong Kong
2022
Guiyang Medical University
2021
Abstract Commensal Bacteroides fragilis possesses immune-regulatory characteristics. Consequently, it has been proposed as a potential novel probiotic because of its therapeutic effects on immune imbalance, mental disorders and inflammatory diseases. Macrophages play central role in the response, developing either classical-M1 or an alternative-M2 phenotype after stimulation with various signals. The interactions between macrophages B. , however, remain to be defined. Here, new isolate...
Antibiotic-associated diarrhea (AAD) is iatrogenic characterized by disruption of the gut microbiota. Probiotics are routinely used to treat AAD in clinical practice; however, effectiveness and mechanisms which probiotics alleviate symptoms remain poorly understood. We previously isolated a non-toxic Bacteroides fragilis (B. fragilis) strain ZY-312, has been verified be beneficial certain infection disorders. However, precise role this commensal bacterium unknown. In study, we successfully...
Absolute displacement signals of vibrating platforms/objects are often needed in vibration control, signal processing, and object tracking. Motivated by the practical requirement engineering applications, this study presents analysis design a novel bioinspired dynamics sensor system for absolute measurement. The is constructed using simple beams springs, which indicates possible way achieving nonlinear quasi-zero stiffness consequently creating broadband vibration-free point measurement...
Most bacteria in the human gut are difficult to culture, and culturomics has been designed overcome this issue. Culturomics makes it possible obtain living for further experiments, unlike metagenomics. However, is work-intensive, which prevents its wide application. In study, we performed a 30-day continuous enrichment blood culture bottles cultured bacterial isolates from pre-cultures removed at different time points. We compared isolated enriched with or without adding fresh medium after...
Bacteroides fragilis is an anaerobic, Gram-negative, commensal bacterium of the human gut. It plays important role in promoting maturation immune system, as well suppressing abnormal inflammation. Many recent studies have focused on relationship between B. and immunity, indicate that has many useful probiotic effects. As inhibition intestinal pathogens characteristic strains, this study examined whether could inhibit pathogenic bacteria. Results showed Vibrio parahaemolyticus was inhibited...
This paper proposes a bioinspired reference model based fuzzy adaptive tracking control for active suspension systems. A general nonlinear structure, which can present ideal quasi-zero stiffness vibration isolation, is adopted as model. Fuzzy logic systems are used to approximate unknown terms in Particularly, damping designed improve characteristics of the With beneficial and improved model, proposed controller effectively suppress with less actuator force much ride comfort, thus energy...
In this paper, the event-triggered robust filtering problem is investigated for a class of network-based state-dependent uncertain systems in sense finite-time boundedness, considering network transmission delay. By resorting to generalized performance index, H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> and L xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> - problems can be solved unified framework. An scheme also utilized sift...
Most mobile robots have very simple passive suspension based on conventional mass-spring-damper methods, which bring a trade-off between loading capacity and vibration isolation, or no at all with only hard contact wheels ground. This article presents tracked robot unique suspension, is constructed by using bio-inspired animal-limb-like structure, to guarantee both isolation performance. With the novel capacity, riding comfort obstacle negotiation capability of in various rough ground...
Although the role and mechanism of neutrophils in tumors have been widely studied, precise effects aryl hydrocarbon receptor nuclear translocator (ARNT) on remain unclear. In this study, we investigated roles ARNT function CD11b+Gr1+ colitis-associated colorectal cancer. Wild-type (WT), myeloid-specific deficient mice a cancer mouse model were used study. The level functions cells evaluated by flow cytometry confocal microscopy. We found that deficiency drives recruitment, neutrophil...
This study aimed to explore the relationship between changes in early degradation products of polysaccharide coatings (such as hyaluronic acid (HA), syndecan-1 (SDC-1), and heparan sulfate (HS)) development organ dysfunction sepsis patients. We conducted a retrospective analysis on 140 patients admitted from January 2021 June 2022, who formed group; 100 healthy individuals underwent health checks during same period were included control group. The found that expression levels HA, SDC-1, HS...
This paper investigates the extended dissipative filter design problems for continuous-time fuzzy systems with time-varying delays under imperfect premise variables based on a unified performance index−extended dissipative. Attention is focused solving H∞, L2 − L∞, passive and filtering this framework. Based index, new delay-dependent approach in terms of linear matrix inequalities obtained by employing Lyapunov–Krasovskii functional method together novel efficient integral inequality. The...
As a pair of differential isomers, Kaji-ichigoside F1 and Rosamultin are both pentacyclic triterpenoids isolated from the subterranean root Potentilla anserina L., plant used in folk medicine western China as antihypoxia anti-inflammatory treatments. We demonstrated that effectively prevented hypoxia-induced apoptosis vascular endothelial cells. established hypoxia model, using EA.hy926 cells, to further explore mechanisms. Hypoxia promoted phosphorylation AKT, ERK1/2, NF- κ B. In hypoxic...
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is the most prevalent and characterized by excessive fat accumulation. Kaili Sour Soup, a food typical of Guizhou Province, believed to have significant health benefits. Thus, we aimed identify assess impact Soup on NAFLD its underlying mechanism using integrative proteomic lipidomic analysis. Methods A high-fat diet male Wistar rats were used construct rat model. Haematoxylin eosin (HE) Oil Red O staining analyses perform...
Background: Vitamin D deficiency has been associated with increased sepsis incidence and mortality in various populations. exerts its effect through vitamin receptor (VDR), single nucleotide polymorphisms have reported to affects the expression structure of VDR. In present study, we investigated possible role VDR susceptibility sepsis.Methods: 576 patients 421 healthy controls were enrolled study. Plasma levels quantified by ELISA. Genetic variants (FokI, TaqI, BsmI, ApaI) genotyped TaqMan...
Abstract Background Culturomics can ascertain traces of microorganisms to be cultivated using different strategies and identified by matrix-assisted laser desorption/ionization–time-of-flight mass spectrometry or 16S rDNA sequencing. However, cater all requirements isolate as many species possible, multiple culture conditions must used, imposing a heavy workload. In addition, the fast-growing bacteria (e.g., Escherichia ) surpass slow-growing in occupying space up nutrients. Besides, some...
In this article, we investigate sequential power allocation over fast varying channels for mission-critical applications, aiming to minimize the expected sum while guaranteeing transmission success probability. particular, a reinforcement learning framework is constructed with appropriate reward design so that optimal policy maximizes Lagrangian of primal problem, where maximizer shown have several good properties. For model-based case, converging algorithm proposed find Lagrange multiplier...