A5101965689- Tuberculosis Research and Epidemiology
- Gastrointestinal disorders and treatments
- Mycobacterium research and diagnosis
- Colorectal Cancer Screening and Detection
- Congenital gastrointestinal and neural anomalies
- Antibiotic Resistance in Bacteria
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Vascular anomalies and interventions
- Cerebrovascular and Carotid Artery Diseases
- Kruppel-like factors research
- Central Venous Catheters and Hemodialysis
- Clinical Nutrition and Gastroenterology
- Immune cells in cancer
- Amoebic Infections and Treatments
- Neuroscience and Neuropharmacology Research
- Pleural and Pulmonary Diseases
- Diverticular Disease and Complications
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Bioactive Compounds and Antitumor Agents
- Gastrointestinal motility and disorders
- Liver Diseases and Immunity
- Long-Term Effects of COVID-19
Beijing Chest Hospital
2022-2025
Capital Medical University
2021-2025
Taiyuan Central Hospital
2025
Lanzhou University
2022-2023
Beijing Children’s Hospital
2021-2023
First Hospital of Lanzhou University
2022-2023
Capital University
2022
Beijing Chao-Yang Hospital
2021
NewYork–Presbyterian Hospital
2011
Cornell University
2011
<title>Abstract</title> <bold>Background</bold>: There is currently insufficient evidence regarding the relationship between composite dietary antioxidant index (CDAI) and peripheral artery disease (PAD). This association of significant importance for both individual public health. Understanding correlation CDAI PAD an increasingly relevant topic research. Objective: study aimed to investigate occurrence PAD. <bold>Methods</bold>: A retrospective cross-sectional was conducted, participants...
<title>Abstract</title> <bold>Objective:</bold>To investigate the treatment of acute appendicitis in children with malignant tumors. <bold>Methods: </bold>We retrospectively analyzed clinical data 31 tumors who were diagnosed at Beijing Children's Hospital from March 2007 to October 2023. <bold>Results: </bold>The mean age was 5.2 (3.1, 8.8) years, and male-to-female ratio 4.2:1. The most common tumor lymphoblastic leukemia (22, 71%). main manifestations abdominal pain (23, 74%) fever (27,...
For complex right colon polyps, not removable using colonoscopy, resection is considered the optimal treatment. Combined endoscopic-laparoscopic surgery, both laparoscopy and CO2 has been introduced as a new approach for these polyps with intent to avoid bowel resection.This study aimed evaluate safety outcomes of combined surgery used treatment polyps.This retrospective patients undergoing benign from 2003 2008.This single-institution study.Twenty-three were included.The main outcome...
Background Pulmonary non-tuberculous mycobacteria (NTM) infection has become a public health concern in China and around the world. The objective of this study was to describe longitudinal changes frequency diversity NTM northern China. Methods We retrospectively analyzed data on mycobacterium species Beijing Chest Hospital from January 2014 December 2021. isolates were identified level by targeted DNA sequencing. Results After excluding duplicates, 1,755 strains analyzed, which 27 provinces...
Background Tuberculosis (TB) is caused by Mycobacterium tuberculosis ( Mtb ) and remains a major health threat worldwide. However, detailed understanding of the immune cells inflammatory mediators in -infected tissues still lacking. Tuberculous pleural effusion (TPE), which characterized an influx to space, thus suitable platform for dissecting complex tissue responses infection. Methods We employed singe-cell RNA sequencing 10 fluid (PF) samples from 6 patients with TPE 4 non-TPEs including...
[11C]ER176 has adequate sensitivity to image the human brain translocator protein (TSPO) in all three genotypes by positron emission tomography (PET). However, its clinical application is limited short half-life of 11C (20.38 min). To overcome deficiency and keep pharmacophore features ER176 maximum extent, we designed four fluorine-labeled derivatives using deuterium method. In vitro competition binding confirmed that compounds had high affinity for TSPO. Biodistribution experiments showed...
This study is aimed at investigating mechanisms and effects of Krüppel-like factor 16 (KLF16) affects myocardial ischemia-reperfusion. Patients with ischemia-reperfusion normal volunteer were collected. C57BL6J male mice located left anterior descending coronary artery (LAD). H9c2 cell was induced hydrogen peroxide (H2O2) Lipopolysaccharide (LPS). Serum KLF16 mRNA expression increased in positive correlation serum creatine kinase MB (CK-MB) or (CK) levels patients The protein also increased....
Tubercidin is an adenosine analogue that has been shown to exhibit good activity against some tumours and parasites. In this study, the in vitro of tubercidin was evaluated Mycobacterium tuberculosis (Mtb) nontuberculosis Mycobacteria (NTM). For determining MICs tubercidin, 23 fully drug-sensitive (DS) Mtb strains, 33 multi-drug resistance (MDR-TB) 29 pre-extensively drug-resistant (pre-XDR-TB) 21 extensively (XDR-TB) 17 rapidly growing mycobacteria (RGM) nine slowly (SGM) references strains...
Abstract Background The incidence of colorectal cancer among the middle-aged and elderly is gradually increasing in China. Colonoscopy an effective method for early diagnosis cancer, bowel preparation one many important factors affecting colonoscopy. Although there are studies on intestinal cleansers, results not ideal. There evidence that hemp seed oil has certain potential effects cleansing, but prospective this topic still lacking. Methods This a randomized, double-blind, single-center...
Abstract Tuberculosis (TB) was the leading cause of death from a single infectious agent before coronavirus pandemic. Therefore, it is important to search for severity biomarkers and devise appropriate therapies. A total 139 pulmonary TB (PTB) patients 80 healthy controls (HCs) were recruited plasma soluble CD137 (sCD137) detection through ELISA. Moreover, pleural effusion sCD137 levels measured in 85 36 untreated lung cancer patients. The cytokine 64 with PTB blood immune cell...
Introduction. Aminoglycoside antibiotics such as amikacin and kanamycin are important components in the treatment of Mycobacterium tuberculosis (Mtb) infection. However, more clinical strains found to be aminoglycoside antibiotic-resistant. Apramycin is another kind antibiotic that commonly used treat infections animals. Hypothesis. may have vitro activity against Mtb. Aim. This study aims evaluate efficacy apramycin Mtb determine its epidemiological cut-off (ECOFF) value. Methodology. One...
Introduction. Pre-existing fluoroquinolones (FQs) resistance is a major threat in treating multidrug-resistant (MDR) tuberculosis. Sitafloxacin (Sfx) new broad-spectrum FQ. Hypothesis. Sfx more active against drug-resistant Mycobacterium tuberculosis (Mtb) isolates. Aim. To determine whether there cross-resistance between and ofloxacin (Ofx), levofloxacin (Lfx) moxifloxacin (Mfx) MDR Mtb. Methods. A total of 106 clinical Mtb isolates, including 23 pan-susceptible 83 strains, were analysed...
We treated a neonate who was diagnosed as rapidly involuting congenital hemangioma (RICH). With review on the clinical manifestation, differential diagnosis, and treatment of RICH that associated with thrombocytopenia(TP)and coagulopathy(CP)and received platelet transfusions embolization therapy including absolute ethanol polidocanol in our hospital March 2015. The platelets coagulation function soon returned to normal, tumor involuted significantly. Surgical excision proceeded subsequently....
Background: Coronavirus disease 2019 (COVID-19) and tuberculosis (TB) are two important respiratory infectious diseases with significant public health threats. Their co-infection (COVID-19-TB) have the potential to exacerbate lung damage. However, there only been a few reports focused on COVID-19-TB cases so far, limited information available about clinical features of patients. The aim this study was clarify characteristics outcomes patients COVID-19 TB co-infection. Methods: In...
Objective To compare the effect of self-gripping mesh and conventional polypropylene in laparoscopic totally extraperitoneal hernioplasty (TEP). Methods 160 patients with inguinal hernia admitted to Kaizhou district Traditional Chinese Medicine hospital from January 2016 2018 were selected as research objects, their clinical data retrospectively analyzed. All treated TEP, they divided into experimental group (n=87) control (n=73) according difference used during operation. The two...
Abstract Purpose To evaluate the clinical features, surgical management, and prognosis of ileocecal duplication in children. Methods A total 115 patients diagnosed with at Beijing Children’s Hospital between January 2010 June 2021 were retrospectively reviewed. Ileocecal duplications divided into ileal extraluminal (n = 24), intraluminal 41), valve 11), cecal 3), 18) types according to their locations. Results Mean age diagnosis was 9.5 (0.1-169.2) months. Intussusception only observed...