A5032444299- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Occupational and environmental lung diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Tracheal and airway disorders
- Trauma Management and Diagnosis
- Pneumothorax, Barotrauma, Emphysema
- Lung Cancer Treatments and Mutations
- Inhalation and Respiratory Drug Delivery
- Salivary Gland Tumors Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Cancer Genomics and Diagnostics
- Cancer Diagnosis and Treatment
- IgG4-Related and Inflammatory Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Glioma Diagnosis and Treatment
- Lymphatic Disorders and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Myasthenia Gravis and Thymoma
- Respiratory Support and Mechanisms
- Eosinophilic Disorders and Syndromes
- Radiomics and Machine Learning in Medical Imaging
- Soft tissue tumor case studies
- Ear and Head Tumors
Zealand University Hospital
2020-2024
University of Southern Denmark
2020-2024
Gentofte Hospital
2024
Copenhagen University Hospital
2024
Odense University Hospital
2024
Forskning.no (Norway)
2024
Næstved Sygehus
2020
Background The optimal management for spontaneous pneumothorax (SP) remains contentious, with various proposed approaches. This joint clinical practice guideline from the ERS, EACTS and ESTS societies provides evidence-based recommendations of SP. Methods multidisciplinary Task Force addressed 12 key questions on pneumothorax, using ERS methodology development. Systematic searches were performed in MEDLINE Embase. Evidence was synthesised by conducting meta-analyses, if possible, or...
Background: Non-expandable lung (NEL) has severe implications for patient symptoms and impaired function, as well crucial the management of malignant pleural effusion (MPE). Indwelling catheters have shown good symptom relief patients with NEL; hence, identifying early in their disease is vital. With inability to achieve apposition following thoracentesis formation a hydropneumothorax, traditionally, chest X-ray clinical been used make diagnosis thoracentesis. It our aim investigate whether...
Abstract OBJECTIVES The optimal management for spontaneous pneumothorax (SP) remains contentious, with various proposed approaches. This joint clinical practice guideline from the ERS, EACTS and ESTS societies provides evidence-based recommendations of SP. METHODS multidisciplinary Task Force addressed 12 key questions on pneumothorax, using ERS methodology development. Systematic searches were performed in MEDLINE Embase. Evidence was synthesised by conducting meta-analyses, if possible, or...
Introduction We present findings from the International Collaborative Effusion database, a European Respiratory Society clinical research collaboration. Nonspecific pleuritis (NSP) is broad term that describes chronic pleural inflammation. Various aetiologies lead to NSP, which poses diagnostic challenge for clinicians. A significant proportion of patients with this finding eventually develop malignant diagnosis. Methods 12 sites across nine countries contributed anonymised data on 187...
Background Chylothorax is an uncommon medical condition for which limited data are available regarding the contemporary aetiology, management and outcomes. The goal of this study was to better define these poorly characterised features. Methods records adult patients diagnosed with chylothorax at 12 centres across Europe, America South Africa from 2009–2021 were retrospectively reviewed. Descriptive inferential statistics performed. Results 77 (median age 69 years, male female ratio 1.5)...
Inhaled corticosteroids (ICS) are associated with an increased risk of clinical pneumonia among patients chronic obstructive pulmonary disease (COPD). It is unknown whether the microbiologically verified such as pneumococcal in ICS users.The study population consists all COPD followed outpatient clinics eastern Denmark during 2010-2017. use was categorized into four categories based on accumulated use. A Cox proportional hazard regression model used adjusting for age, body mass index, sex,...
Background: The value of pre-booked repeated thoracentesis in patients with recurrent pleural effusion is reliant on the estimation time to next drainage. Identifying factors associated rapid fluid recurrence could be supportive. Objective: We aimed evaluate ability patient and physician predict therapeutic identify characteristics recurrence. Method: In a prospective, observational study, unilateral were symptom-guided thoracentesis. Primary outcome was difference between days actual...
Ultrasound-guided needle aspiration via the esophagus using endobronchial endoscope (EUS-B-FNA) is increasingly being performed by pulmonologist for diagnosis of lung cancer, but we have little experience and data available in literature especially with respect to staging disease. We present 2 cases EUS-B-guided malignant pericardial effusion same setting as bronchoscopy ultrasound. No complications were observed. conclude that EUS-B-FNA may be safe efficacious evaluation during cancer...
Malignant pleural effusion is an important and difficult differential diagnosis to empyema. Epithelioid hemangioendothelioma uncommon vascular tumor, which typically occurs in liver, lung or bone. We present extremely rare case of primary epithelioid mimicking conclude, that should be kept mind as a patients suspected
The incidence of pleural disease is increasing and the mortality morbidity high. Many recent RCTs have resulted in evidence-based guidelines published 2023, pointing towards a more individualized specialized management. Most patients with are admitted at A & E but can be managed outpatient clinics. Thus, there need to establish specialized, multidisciplinary clinics ensure optimal, management number Denmark, as argued this review.
Background In patients with recurrent pleural effusion, therapeutic thoracentesis is one way of relief. Correct prediction which will experience relief following drainage may support the management these patients. This study aimed to assess association between ultrasound (US) characteristics and a relevant improvement in dyspnoea immediately drainage.
Background: Malignant pleural effusion (MPE) affects up to 15% of patients with malignancy, and the prevalence is increasing. Non-expandable lung (NEL) complicates MPE in 30% cases. However, it not known if malignant NEL are more symptomatic activities daily living compared expandable lung. Methods: This was an observational study on consecutively recruited from our clinic. Before thoracentesis, completed patient-reported outcomes cancer symptoms (ESAS), health-related quality life...
Abstract INTRODUCTION Patients with glioblastoma, the most aggressive primary brain tumor, lack effective treatment despite advancements in molecular understanding. This study aims to develop and validate a prognostic model integrating genomic alterations clinical factors newly diagnosed glioblastoma patients undergoing standard radiation therapy concomitant adjuvant temozolomide. MATERIALS AND METHODS From our prospective database, all consecutive IDH-wildtype who received at Rigshospitalet...
Background: In patients with pleural effusion, specific ultrasound characteristics are associated malignancy. Objectives: This study aimed to evaluate the added value of an additional, up-front, systematic thoracic (TUS) standard imaging in unilateral effusion unknown cause a clinical setting. Methods: prospective observational pilot study, referred for workup and thoracentesis received up-front TUS following set protocol addition available US guiding or diagnostic puncture. The primary...
Abstract Immunoglobulin G4 (IgG4)‐related disease is a systemic fibroinflammatory disorder that can affect almost any tissue. Isolated IgG4 pleural rare manifestation and, when present, usually described in patients presenting with dyspnoea. We present case of asymptomatic isolated effusion and highlight IgG4‐related should be remembered as differential diagnosis thickening, even if without other organ involvement.
Dental care workers are frequently exposed to various types of volatile organic and inorganic compounds. In addition biological materials, these compounds include silica, heavy metals, acrylic plastics. Such exposures may cause respiratory symptoms, but the nonspecific nature symptoms often means that etiology is difficult discern. The disease severity depends on particle size type inhaled compounds, as well duration intensity exposure, which varies markedly among dental workers. Here, we...
Oncological treatment of primary pulmonary adenocarcinoma (AC) includes drugs targeting the pathways involving programmed death-ligand 1 (PD-L1), epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK). The aim study was to report prevalence these tumour markers in pleural fluid with cytology positive for AC potential influence volume tested.We retrospectively reviewed all thoracenteses performed a two-year period at our interventional unit Department...
Bronchoscopy and endobronchial ultrasound (EBUS) are standard procedures for the diagnosis staging of patients suspected lung cancer. If patient simultaneously presents with suspicious liver lesions, it is tradition to refer a radiologist ultrasound-guided percutaneous biopsy.The aim this study was investigate results complications when pulmonologist performs all three in same setting.We retrospectively identified who during 2018-2020 underwent invasive workup cancer metastases lesion biopsy...
Die ultraschallgestützte Feinnadelaspiration mit Zugang über den Ösophagus unter Verwendung eines endobronchialen Endoskops (EUS-B-FNA) wird von Pneumologen zunehmend für die Diagnose Lungentumoren angewendet. Bislang liegen uns jedoch nur wenige Erfahrungen und Daten aus der Literatur das Staging Erkrankung vor. Wir stellen hier 2 Fälle einer EUS-B-gestützten Aspiration malignen Perikardergusses vor, denselben Bedingungen wie eine Bronchoskopie endobronchiale Ultraschalluntersuchung...
<b>Introduction and Background:</b> Targeted oncological treatment of non-small cell lung cancer (NSCLC) requires assessment oncodriver status: Epidermal growth factor receptor (EGFR), programmed death-ligand 1 (PD-L1), anaplastic lymphoma kinase (ALK) in adenocarcinomas (AC), PD-L1 squamous carcinomas (SCC). The sensitivity thoracentesis for providing a diagnosis malignant pleural effusion (MPE) secondary to AC is ~80% ~15% SSC but not established concerning status (1). <b>Aims...
<b>Background:</b> Inhaled corticosteroids(ICS) are associated with an increased risk of clinical pneumonia among patients COPD. <b>Aims:</b> Investigating whether the microbiologically verified pneumococcal is in ICS users a dose-depend manner. <b>Methods:</b> The study population consists all COPD followed outpatient clinics eastern Denmark. use was categorized into four categories based on accumulated use. A Cox proportional hazard regression model used adjusting for age, BMI, sex,...
<b>Background:</b> We present findings from the International Collaborative Effusion (ICE) database, an ERS clinical research collaboration. Non-specific pleuritis (NSP) is a broad term that describes chronic pleural inflammation. Various aetiologies lead to this histological finding and pose diagnostic challenge. A significant proportion of patients with histology eventually develop malignant diagnosis <b>Methods:</b> 12 sites across 9 countries contributed data on 175 patients. Descriptive...