- Neuroendocrine regulation and behavior
- Zebrafish Biomedical Research Applications
- Evolutionary Psychology and Human Behavior
- Animal Behavior and Reproduction
- Cephalopods and Marine Biology
- Neuropeptides and Animal Physiology
- Infant Nutrition and Health
- Marine animal studies overview
- Caveolin-1 and cellular processes
- Neurobiology and Insect Physiology Research
- Pancreatitis Pathology and Treatment
Max Planck Institute for Brain Research
2020-2022
University of Veterinary Medicine Hannover, Foundation
2016
Zebrafish are highly social teleost fish and an excellent model to study behavior. The neuropeptide Oxytocin is associated different behaviors as well disorders resulting in impairment like autism spectrum disorder. However, how receptor signaling affects the development expression kinetics of behavior not known. In this we investigated role two oxytocin receptors, Oxtr Oxtrl, maintenance preference shoaling 2- 8-week-old zebrafish. Using CRISPR/Cas9 mediated oxtr oxtrl knock-out fish, found...
Behavior is context-dependent and often modulated by an animal's internal state. In particular, different social contexts can alter anxiety levels modulate behavior. The vertebrate-specific neuropeptide parathyroid hormone 2 (pth2) regulated the presence of conspecifics in zebrafish. As its cognate receptor, receptor (pth2r), widely expressed across brain, we tested fish lacking functional Pth2 peptide several anxiety-related behavior paradigms. Here, show that propensity to react sudden...
During lactation, mineral and nutrient requirements increase dramatically, particularly those for Ca glucose. In contrast to monogastric species, in ruminants, it is rather unclear which extend this physiological change due increased demand milk production accompanied by functional adaptations of the gastrointestinal tract (GIT). Therefore, we investigated potential modulations glucose transport mechanisms GIT lactating dried-off sheep. Ussing-chamber technique was applied determine ruminal...
Abstract Zebrafish are highly social teleost fish and an excellent model to study behavior. The neuropeptide Oxytocin is associated different behaviors as well disorders resulting in impairment like autism spectrum disorder. However, how receptor signaling affects the development expression kinetics of behavior not known. In this we investigated role two oxytocin receptors, Oxtr Oxtrl, maintenance preference shoaling 2- 8-week-old zebrafish. Using CRISPR/Cas9 mediated oxtr oxtrl knock-out...
Summary Animal behavior is strongly context-dependent and behavioral performance often modulated by internal state. In particular, different social contexts can alter anxiety levels modulate behavior. The vertebrate-specific neuropeptide parathyroid hormone 2 ( pth2 ) directly regulated the presence or absence of conspecifics in zebrafish. As its cognate receptor, receptor pth2r ), widely expressed across brain, we tested fish lacking functional Pth2 peptide several anxiety-related...